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Lia Ferreira, João Silva, Susana Garrido, Carlos Bello, Diana Oliveira, Hélder Simões, Isabel Paiva, Joana Guimarães, Marta Ferreira, Teresa Pereira, Rita Bettencourt-Silva, Ana Filipa Martins, Tiago Silva, Vera Fernandes, Maria Lopes Pereira and Adrenal Tumors Study Group of the Portuguese Society of Endocrinology

Introduction Addison disease (AD) or primary adrenal insufficiency (PAI) is a life-threatening disease that results from bilateral destruction or dysfunction of the adrenal cortex ( 1 ). PAI is a rare disease with a reported prevalence of

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Kathrin Zopf, Kathrin R Frey, Tina Kienitz, Manfred Ventz, Britta Bauer and Marcus Quinkler

AC might be influenced by the Bcl I polymorphism. Therefore, we included 72 patients with adrenal insufficiency (47 patients with primary adrenal insufficiency (PAI) and 25 patients with congenital adrenal hyperplasia (CAH)) in a prospective

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Kathrin R Frey, Tina Kienitz, Julia Schulz, Manfred Ventz, Kathrin Zopf and Marcus Quinkler

Introduction In states of adrenal insufficiency (AI), such as primary adrenal insufficiency (PAI) and congenital adrenal hyperplasia (CAH), glucocorticoids (GCs) are given in low doses as hormone replacement therapy. However, the daily intake

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Hiren Patt, Katrin Koehler, Sailesh Lodha, Swati Jadhav, Chaitanya Yerawar, Angela Huebner, Kunal Thakkar, Sneha Arya, Sandhya Nair, Manjunath Goroshi, Hosahithlu Ganesh, Vijaya Sarathi, Anurag Lila, Tushar Bandgar and Nalini Shah

. ( doi:10.1073/pnas.0505598103 ) 10.1073/pnas.0505598103 7 Bornstein SR Allolio B Arlt W Barthel A Don-Wauchope A Hammer GD Husebye ES Merke DP Murad MH Stratakis CA Diagnosis and treatment of primary adrenal insufficiency: an Endocrine Society

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Marcus Quinkler, Bertil Ekman, Claudio Marelli, Sharif Uddin, Pierre Zelissen, Robert D Murray and on behalf of the EU-AIR Investigators

-AIR, European Adrenal Insufficiency Registry; PAI, primary adrenal insufficiency; SAI, secondary adrenal insufficiency; s.d. , standard deviation. After predefining the matching cohorts, we performed a 1:3 matching of patients on prednisolone

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Ghazala Zaidi, Vijayalakshmi Bhatia, Saroj K Sahoo, Aditya Narayan Sarangi, Niharika Bharti, Li Zhang, Liping Yu, Daniel Eriksson, Sophie Bensing, Olle Kämpe, Nisha Bharani, Surendra Kumar Yachha, Anil Bhansali, Alok Sachan, Vandana Jain, Nalini Shah, Rakesh Aggarwal, Amita Aggarwal, Muthuswamy Srinivasan, Sarita Agarwal and Eesh Bhatia

#240300) ( 1 , 2 ). It is diagnosed by the presence of at least two of three major components: chronic mucocutaneous candidiasis (MCC), hypoparathyroidism (HP) and primary adrenal insufficiency (PAI) ( 3 , 4 , 5 , 6 , 7 ). In addition, it is

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Wiebke Arlt and the Society for Endocrinology Clinical Committee

and prompt management can save lives. This guideline aims to take the non-specialist through the initial phase of assessment and management. Underlying conditions Primary adrenal insufficiency is caused by loss of function of the adrenal gland

Open access

Marie Freel

this guideline is Professor Weibke Arlt who was also an author on the Endocrine Society Clinical Practice Guideline and the diagnosis and treatment of primary adrenal insufficiency published in 2016 ( 2 ). Severe symptomatic hyponatraemia ( 3 ): this

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L M Mongioì, R A Condorelli, S La Vignera and A E Calogero

, mean age 41 ± 2.67 years) ( Table 1 ) and 9 patients with AI secondary to hypopituitarism (6 men, 3 women, mean age 53.2 ± 17.7 years) ( Table 2 ). Table 1 Biographical and clinical data of patients with primary adrenal insufficiency

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V Guarnotta, C Di Stefano, A Santoro, A Ciresi, A Coppola and C Giordano

 Hypocortisolism + hypogonadism + hypothyroidism 4  Isolated ACTH deficiency 4 Isolated primary adrenal insufficiency 11 Primary adrenal insufficiency in polyglandular autoimmune syndrome  Addison’s disease + autoimmune thyroid