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Bogumila Urgatz Merck Healthcare KGaA, Darmstadt, Germany

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Kris G Poppe University Hospital CHU Saint Pierre, Free University of Brussels, Brussels, Belgium

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Diagnosis of hypothyroidism during pregnancy Evolution of normal thyroid function during pregnancy Circulating levels of human chorionic gonadotrophin (hCG) increase from about 11 days post conception, reach a peak around the end of the

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Deirdre Green Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin

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Rosemary Dineen Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin

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Michael W O’Reilly Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin

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Mark Sherlock Academic Department of Endocrinology, Beaumont Hospital and the Royal College of Surgeons in Ireland, Dublin

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of adrenal crisis ( 2 ), and premature mortality ( 13 , 14 ). In patients of reproductive age, AI may have consequences on fertility, reproduction, and pregnancy outcomes ( 15 , 16 ). Patients with AI on optimal GC replacement pre-conception are

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Anette Lundqvist Department of Public Health and Clinical Medicine, Family Medicine, Umeå University, Umeå, Sweden

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Herbert Sandström Department of Public Health and Clinical Medicine, Family Medicine, Umeå University, Umeå, Sweden

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Torbjörn Bäckström Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, Umeå, Sweden

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Introduction Maternal obesity and excessive weight gain during pregnancy is a condition that increases the risk of several complications for both the mother and the growing fetus, with a risk that the fetus will suffer from a suboptimal

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Kathryn L Gatford Robinson Research Institute, The University of Adelaide, Adelaide, Australia
Adelaide Medical School, The University of Adelaide, Adelaide, Australia

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Beverly S Muhlhausler FOOD plus Research Centre, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, Australia

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Lili Huang School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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Pamela Su-Lin Sim FOOD plus Research Centre, School of Agriculture, Food and Wine, The University of Adelaide, Adelaide, Australia

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Claire T Roberts Robinson Research Institute, The University of Adelaide, Adelaide, Australia
Adelaide Medical School, The University of Adelaide, Adelaide, Australia

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Johannes D Velhuis Endocrine Research Unit, Mayo School of Graduate Medical Education, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota, USA

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Chen Chen School of Biomedical Sciences, University of Queensland, St Lucia, Brisbane, Australia

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Introduction Successful pregnancy requires major physiological adaptations in the mother to support pregnancy, and the attachment, implantation, growth and function of the placental interface between mother and foetus ( 1 ). Growth hormone (GH

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Caio Jordão Teixeira Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

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Junia Carolina Santos-Silva Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

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Dailson Nogueira de Souza Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

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Alex Rafacho Department of Physiological Sciences, Center of Biological Sciences, Federal University of Santa Catarina, Florianópolis, Brazil

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Gabriel Forato Anhe Department of Pharmacology, Faculty of Medical Sciences, State University of Campinas, Campinas, Brazil

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Silvana Bordin Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil

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hyperglycemia in nondiabetic women ( 3 , 4 ). Concordantly, experiments with rats showed that exposure to dexamethasone (DEX) during the last third of pregnancy impaired maternal glucose-induced insulin secretion in vivo , leading to glucose intolerance prior

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Aglaia Kyrilli Department of Endocrinology, Hôpital Universitaire de Bruxelles (H.U.B.) - Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Bernard Corvilain Department of Endocrinology, Hôpital Universitaire de Bruxelles (H.U.B.) - Hôpital Erasme, Université Libre de Bruxelles (ULB), Brussels, Belgium

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Sofie Bliddal Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
Department of Gynecology and Obstetrics, Copenhagen University Hospital (Hvidovre Hospital), Hvidovre, Denmark

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Dorthe Hansen Precht Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
Carelink Nærhospital, Roskilde, Denmark

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Ulla Feldt-Rasmussen Department of Medical Endocrinology and Metabolism, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
Institute of Clinical Medicine, Faculty of Health and Clinical Research, Copenhagen University, Copenhagen, Denmark

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Kris Poppe Department of Endocrinology, Centre Hospitalier Universitaire Saint-Pierre, Brussels, Belgium
Université Libre de Bruxelles (ULB), Brussels, Belgium

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, depending on the iodine intake in the investigated area and the ethnic background ( 1 , 2 , 3 , 4 , 5 , 6 ). TAI is the strongest predictor for the development of subclinical or overt thyroid dysfunction in the preconception, during pregnancy, and in

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Yessica Agudelo-Zapata Division of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Luis Miguel Maldonado-Acosta Division of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Héctor Fabio Sandoval-Alzate Department of Human Nutrition, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Natalia Elvira Poveda Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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María Fernanda Garcés Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Jonathan Alexander Cortés-Vásquez Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Andrés Felipe Linares-Vaca Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Carlos Alejandro Mancera-Rodríguez Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Shahar Alexandra Perea-Ariza Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Karen Yuliana Ramírez-Iriarte Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Camilo Andrés Castro-Saldarriaga Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Juan Manuel Arteaga-Diaz Division of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Roberto Franco-Vega Division of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Edith Ángel-Müller Department of Obstetrics and Gynecology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Arturo José Parada-Baños Department of Obstetrics and Gynecology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Jorge E Caminos Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Introduction There is a high prevalence of 25-hydroxyvitamin D (25OHD) deficiency during pregnancy ( 1 ). In the United States, a prevalence of 33% has been reported, while in countries such as Turkey, the prevalence reaches 90% ( 1 ). 25OHD

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Stine Linding Andersen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Louise Knøsgaard Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Aase Handberg Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Peter Vestergaard Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Endocrinology, Aalborg University Hospital, Aalborg, Denmark
Steno Diabetes Center North Jutland, Aalborg University Hospital, Aalborg, Denmark

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Stig Andersen Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark

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Introduction Maternal thyroid function in early pregnancy is a debated matter ( 1 , 2 ). The role of thyroid hormones in fetal brain development has long drawn ample attention to the potential adverse consequences of abnormal maternal thyroid

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Leqi He Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Xiaoying Li Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Zaoping Chen Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Wei Wang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Kai Wang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Xinmei Huang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Qian Yang Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Wencai Ke Department of Clinical Laboratory Medicine, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Jun Liu Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Bingbing Zha Department of Endocrinology, Fifth People’s Hospital of Shanghai Fudan University, Shanghai, China

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Introduction Pregnancy is a unique period of female life when a series of hormone changes jointly regulate thyroid function. Maternal human chorionic gonadotropin (hCG) levels peak at 30,000–100,000 U/L in the eighth to tenth week of gestation

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Stine Linding Andersen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Stig Andersen Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark

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predominantly occurs in female patients and in the reproductive time span, the management of the disease should consider the patient’s reproductive history and the possibility of a current or future pregnancy ( 1 , 2 ). GD is an autoimmune disease caused by

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