Search Results
Search for other papers by Nadia Sawicka-Gutaj in
Google Scholar
PubMed
Search for other papers by Ariadna Zybek-Kocik in
Google Scholar
PubMed
Search for other papers by Michał Kloska in
Google Scholar
PubMed
Search for other papers by Paulina Ziółkowska in
Google Scholar
PubMed
Search for other papers by Agata Czarnywojtek in
Google Scholar
PubMed
Search for other papers by Jerzy Sowiński in
Google Scholar
PubMed
Search for other papers by Dorota Mańkowska-Wierzbicka in
Google Scholar
PubMed
Search for other papers by Marek Ruchała in
Google Scholar
PubMed
Dysregulation of thyroid function has known impact on body metabolism, however, data regarding metabolic outcome after restoration of thyroid function is limited. Therefore, the aim of the study was to investigate the effect of restoration of euthyroidism on serum visfatin, and its associations with insulin resistance and body composition. This is an observational study with consecutive enrollment. Forty-nine hyperthyroid (median age of 34 years) and 44 hypothyroid women (median age of 46 years) completed the study. Laboratory parameters and body composition analysis were assessed before and after the therapy. In the hyperthyroid group, visfatin concentrations increased (P < 0.0001), while glucose concentrations decreased (P < 0.0001). Total body mass and fat mass in the trunk and limbs significantly increased during the treatment. In the hypothyroid group, significant weight loss resulted from decrease of fat and muscle masses in trunk and limbs. Visfatin serum concentrations positively correlated with total fat mass (r = 0.19, P = 0.01) and insulin concentrations (r = 0.17, P = 0.018). In conclusion, restoration of thyroid function is not associated with beneficial changes in body composition, especially among hyperthyroid females.
Search for other papers by Nese Cinar in
Google Scholar
PubMed
Search for other papers by Alper Gurlek in
Google Scholar
PubMed
humans. More studies are needed to clarify the relationship between vaspin and thyroid hormones. Visfatin Visfatin, previously defined as pre-B cell colony-enhancing factor, is a 52-kDa cytokine expressed and secreted by lymphocytes (57) . Visfatin is
Search for other papers by Xuan Luo in
Google Scholar
PubMed
Search for other papers by Tingting Zheng in
Google Scholar
PubMed
Institute of Oncology, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
Search for other papers by Chaoming Mao in
Google Scholar
PubMed
Search for other papers by Xin Dong in
Google Scholar
PubMed
Search for other papers by Xiao Mou in
Google Scholar
PubMed
Search for other papers by Chengcheng Xu in
Google Scholar
PubMed
Search for other papers by Qingyan Lu in
Google Scholar
PubMed
Search for other papers by Baocui Liu in
Google Scholar
PubMed
Search for other papers by Shengjun Wang in
Google Scholar
PubMed
Search for other papers by Yichuan Xiao in
Google Scholar
PubMed
Pathology 2002 161 195 – 206 . ( https://doi.org/10.1016/S0002-9440(10)64171-5 ) 10.1016/S0002-9440(10)64171-5 24 Chen MP Chung FM Chang DM Tsai JC Huang HF Shin SJ Lee YJ . Elevated plasma level of visfatin/pre-B cell colony-enhancing
Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
Search for other papers by Fei Wu in
Google Scholar
PubMed
Search for other papers by Chaoming Mao in
Google Scholar
PubMed
Search for other papers by Xiao Mou in
Google Scholar
PubMed
Search for other papers by Chengcheng Xu in
Google Scholar
PubMed
Search for other papers by Tingting Zheng in
Google Scholar
PubMed
Search for other papers by Ling Bu in
Google Scholar
PubMed
Search for other papers by Xuan Luo in
Google Scholar
PubMed
Search for other papers by Qingyan Lu in
Google Scholar
PubMed
Search for other papers by Xuefeng Wang in
Google Scholar
PubMed
FM Chang DM Tsai JC Huang HF Shin SJ Lee YJ . Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus . Journal of Clinical Endocrinology and Metabolism 2006 91 295 – 299 . ( https
Search for other papers by Huguette S Brink in
Google Scholar
PubMed
Search for other papers by Aart Jan van der Lely in
Google Scholar
PubMed
Search for other papers by Joke van der Linden in
Google Scholar
PubMed
. ( doi:10.1111/j.1365-2362.2007.01904.x ) 60 Chen MP Chung FM Chang DM Tsai JC Huang HF Shin SJ Lee YJ. Elevated plasma level of visfatin/pre-B cell colony-enhancing factor in patients with type 2 diabetes mellitus