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Cecilia Lundin Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden

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Agota Malmborg Obstetrics and Gynaecology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

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Julia Slezak Clinical Chemistry, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

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Kristina Gemzell Danielsson Department of Women’s and Children’s Health, Karolinska Institutet, and Karolinska University Hospital, Stockholm, Sweden

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Marie Bixo Department of Clinical Science, Obstetrics and Gynaecology, Umeå University, Umeå, Sweden

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Hanna Bengtsdotter Department of Obstetrics and Gynaecology, Örebro University, Örebro, Sweden

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Lena Marions Department of Clinical Science and Education, Karolinska Institutet Södersjukhuset, Stockholm, Sweden

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Ingela Lindh Department of Obstetrics and Gynaecology, Sahlgrenska Academy at Gothenburg University, Sahlgrenska University Hospital, Gothenburg, Sweden

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Elvar Theodorsson Clinical Chemistry, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

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Mats Hammar Obstetrics and Gynaecology, Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

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Inger Sundström-Poromaa Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden

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COC users report decreased sexual desire ( 2 ). At present, despite the bulk of literature, only two randomised placebo-controlled trials have investigated the causal influence of COCs on sexual function ( 3 , 4 ). Both of these studies evaluated a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0384
Volume/Issue:
Volume 7: Issue 11
Open access
Dorte Glintborg Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Magda Lambaa Altinok Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Pernille Ravn Department of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark

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Kurt Bjerregaard Stage Department of Psychiatry, Odense University Hospital, Odense, Denmark

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Kurt Højlund Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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Marianne Andersen Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark

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not aware of previous studies testing this hypothesis. The aim of the present study was to investigate the effect of 12-week escitalopram vs placebo treatment on adrenal activity, mental health, metabolic risk and PCOS phenotype in overweight women

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0077
Volume/Issue:
Volume 7: Issue 3
Open access
Christian Høst Department of Endocrinology and Internal Medicine and the Medical Research Laboratories, Clinical Institute, Aarhus University Hospital, Aarhus N, Denmark
Department of Pediatrics, Aarhus University Hospital, Aarhus N, Denmark

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Anders Bojesen Department of Clinical Genetics, Aarhus University Hospital, Aarhus N, Denmark

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Mogens Erlandsen Section for Biostatistics, Department of Public Health, Aarhus University, Aarhus C, Denmark

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Kristian A Groth Department of Molecular Medicine, Aarhus University Hospital, Aarhus N, Denmark

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Kurt Kristensen Department of Pediatrics, Aarhus University Hospital, Aarhus N, Denmark

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Anne Grethe Jurik Department of Radiology, Aarhus University Hospital, Aarhus N, Denmark

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Niels H Birkebæk Department of Pediatrics, Aarhus University Hospital, Aarhus N, Denmark

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Claus H Gravholt Department of Endocrinology and Internal Medicine and the Medical Research Laboratories, Clinical Institute, Aarhus University Hospital, Aarhus N, Denmark
Department of Molecular Medicine, Aarhus University Hospital, Aarhus N, Denmark

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( 20 ). The present study is the first randomized placebo-controlled study to investigate the effects of testosterone treatment on insulin sensitivity, body composition, muscle strength and maximal oxygen uptake in patients with KS using gold standard

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0323
Volume/Issue:
Volume 8: Issue 9
Open access
Mette Bøgehave Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark

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Dorte Glintborg Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark
OPEN, Open Patient data Explorative Network, Odense University Hospital, Region of Southern Denmark, Odense, Denmark

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Jørgen Brodersen Gram Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark

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Else-Marie Bladbjerg Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark

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Marianne Skovsager Andersen Department of Endocrinology, Odense University Hospital, Odense, Denmark
Department of Clinical Research, University of Southern Denmark, Odense, Denmark

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Johannes Jakobsen Sidelmann Department of Clinical Biochemistry, Hospital South West Jutland, University Hospital of Southern Denmark, Esbjerg, Denmark
Unit for Thrombosis Research, Department of Regional Health Research, University of Southern Denmark, Denmark

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-blinded, placebo-controlled intervention study, we investigate in detail the effect of physiological doses of testosterone on the capacity of the TF and contact activation pathways of coagulation and related coagulation factors and inhibitors in opioid-treated men

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-22-0455
Volume/Issue:
Volume 12: Issue 4
Open access
Niels B Dalsgaard Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

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Lærke S Gasbjerg Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Laura S Hansen Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

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Dennis S Nielsen Department of Food Science, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

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Torben S Rasmussen Department of Food Science, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

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Filip K Knop Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Steno Diabetes Center Copenhagen, Gentofte, Denmark

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impact of acarbose on host GM and health ( 8 , 13 , 14 , 15 ). Here, using faecal samples collected in a previously published randomised double-blind, placebo-controlled clinical trial ( 7 , 16 ), we investigated the effects of a 2-week treatment

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-24-0052
Volume/Issue:
Volume 13: Issue 7
Open access
Chiara Jongerius Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands
Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands

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Marij A Hillen Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands
Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands

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Ellen M A Smets Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands
Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands

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Mathijs J Mol Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands

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Eefje S Kooij Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands

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Maria A de Nood Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands

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Edwin S Dalmaijer MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, United Kingdom

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Eric Fliers Department of Endocrinology & Metabolism, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands

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Johannes A Romijn Department of Medicine, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands

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Daniel S Quintana University of Oslo, Department of Psychology, Oslo, Norway
Department of Rare Disorders and Disabilities, Oslo University Hospital, NevSom, Oslo, Norway
University of Oslo, Norwegian Centre for Mental Disorders Research (NORMENT) and KG Jebsen Centre for Neurodevelopmental Disorders, Oslo, Norway

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-registered, placebo-controlled, randomized experiment, in which we compared the effects of intranasal administration of oxytocin and placebo on the gaze of healthy volunteers toward the eye region of a physician. We expected oxytocin to increase the gaze toward the

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0377
Volume/Issue:
Volume 12: Issue 8
Open access
Sarah Zaheer Division of Endocrinology, Metabolism, and Nutrition, Duke University Medical Center, Durham, North Carolina, USA

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Kayla Meyer Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Boston, Massachusetts, USA

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Rebecca Easly Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Boston, Massachusetts, USA

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Omar Bayomy Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA

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Janet Leung Section of Endocrinology, Virginia Mason Medical Center, Seattle, Washington, USA

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Andrew W Koefoed Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Boston, Massachusetts, USA

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Mahyar Heydarpour Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Boston, Massachusetts, USA

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Roy Freeman Harvard Medical School, Boston, Massachusetts, USA
Department of Neurology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA

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Gail K Adler Division of Endocrinology, Diabetes and Hypertension, Brigham and Women’s Hospital, Boston, Massachusetts, USA
Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA
Harvard Medical School, Boston, Massachusetts, USA

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examining the effect of glucocorticoids vs placebo on sclerostin. This study demonstrated a significant decrease in serum sclerostin with a high (30 mg/day), but not low (7.5 mg/day), dose of prednisolone given over 2 weeks in healthy young men ( 28 ). These

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0263
Volume/Issue:
Volume 10: Issue 12
Open access
Kyoungjune Pak Department of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea

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Seongho Seo Department of Electronic Engineering, Pai Chai University, Daejeon, Republic of Korea

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Myung Jun Lee Department of Neurology, Pusan National University Hospital, Busan, Republic of Korea

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Keunyoung Kim Department of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea

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Sunghwan Suh Department of Internal Medicine, Dong-A University College of Medicine, Busan, Republic of Korea

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Hyung-Jun Im Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Republic of Korea

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In Joo Kim Department of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea

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calculated as follows: weight/height -2 . Bilateral antecubital veins were cannulated: one for blood sampling and for injection of 18 F-FP-CIT and the other for low or high-dose glucose or placebo infusions. The subjects were blinded and randomly assigned

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0355
Volume/Issue:
Volume 10: Issue 10
Open access
Pernille H Hellmann Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Jonatan I Bagger Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark

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Katrine R Carlander Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark

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Katrine B Hansen Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark

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Julie L Forman Section of Biostatistics, Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Joachim Størling Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark

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Elizaveta Chabanova Department of Radiology, Herlev Hospital, University of Copenhagen, Herlev, Denmark

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Jens Holst Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Tina Vilsbøll Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark

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Filip K Knop Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen, Hellerup, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Clinical Research, Steno Diabetes Center Copenhagen, Herlev, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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The study was a single-centre, randomised, double-blind, placebo-controlled, double-dummy, three-arm, parallel-group study conducted from December 2019 to June 2021 at Center for Clinical Metabolic Research, Gentofte Hospital, University of Copenhagen

Article Type:
Research Article
Collections:
Metabolic Syndrome and Diabetes
DOI:
https://doi.org/10.1530/EC-22-0334
Volume/Issue:
Volume 12: Issue 4
Open access
Ermina Bach Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Niels Møller Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Jens Otto L Jørgensen Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark

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Mads Buhl The Neonatal Intensive Care Unit, Aarhus University Hospital, Aarhus, Denmark

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Holger Jon Møller Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark

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. In two placebo-controlled human trials we, therefore, aimed (1) to compare the effects of LPS on levels of sCD163 in hypopituitary patients (HP) (in the absence of pituitary stress hormone responses) and control subjects (CTR) by infusing LPS

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0554
Volume/Issue:
Volume 8: Issue 2
Open access