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Anping Su, Yanping Gong, Wenshuang Wu, Rixiang Gong, Zhihui Li and Jingqiang Zhu

overall costs of thyroid surgery, but also accounts for the main category of thyroidectomy-related claims ( 7 , 8 ). Hypoparathyroidism is caused by injury to the parathyroid glands from ligation of the blood supply, inadvertent or deliberate removal

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Felix Haglund, Gustaf Rosin, Inga-Lena Nilsson, C Christofer Juhlin, Ylva Pernow, Sophie Norenstedt, Andrii Dinets, Catharina Larsson, Johan Hartman and Anders Höög

secretion, DNA synthesis and gene transcription (21, 22, 23, 24) . Oestrogen signalling was suspected to affect parathyroid tumour development but initial results indicated that parathyroid glands in both normal and tumourous states lacked ERA expression

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Elena Pardi, Stefano Mariotti, Natalia S Pellegata, Katiuscia Benfini, Simona Borsari, Federica Saponaro, Liborio Torregrossa, Antonello Cappai, Chiara Satta, Marco Mastinu, Claudio Marcocci and Filomena Cetani

under high-power magnification (×20) were chosen. In each experiment, adjacent normal parenchyma and/or infiltrating lymphocytes served as an internal positive control. Two specimens of normal parathyroid gland, inadvertently removed from normocalcemic

Open access

Maria Mizamtsidi, Constantinos Nastos, George Mastorakos, Roberto Dina, Ioannis Vassiliou, Maria Gazouli and Fausto Palazzo

Introduction Hyperparathyroidism is characterized by hypersecretion of parathyroid hormone (PTH) from the parathyroid glands. According to the cause of hypersecretion, hyperparathyroidism can be classified as primary, secondary or tertiary

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Jeremy Turner, Neil Gittoes, Peter Selby and the Society for Endocrinology Clinical Committee

spasm Laryngospasm ECG changes (prolonged QT interval) and arrhythmia Seizure Potential causes The most common cause of acute symptomatic hypocalcaemia in hospital practice is disruption of parathyroid gland function due to total

Open access

A Chinoy, M Skae, A Babiker, D Kendall, M Z Mughal and R Padidela

Introduction Hypoparathyroidism (HPT) is the partial or complete reduction of parathyroid hormone (PTH) secretion from the parathyroid glands. PTH stimulates 1-alpha-hydroxylase enzyme to produce 1,25(OH) 2 -vitamin D, which facilitates active

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Laura J Reid, Bala Muthukrishnan, Dilip Patel, Mike S Crane, Murat Akyol, Andrew Thomson, Jonathan R Seckl and Fraser W Gibb

imaging modalities were assessed in terms of ability to correctly lateralise disease and also to identify the precise location (i.e. right/left, superior/inferior or ectopic). Pathology Information on the location of the diseased parathyroid gland(s

Open access

Luigia Cinque, Angelo Sparaneo, Antonio S Salcuni, Danilo de Martino, Claudia Battista, Francesco Logoluso, Orazio Palumbo, Roberto Cocchi, Evaristo Maiello, Paolo Graziano, Geoffrey N Hendy, David E C Cole, Alfredo Scillitani and Vito Guarnieri

two of the three ‘P’ glands (pancreas, pituitary, parathyroid) is diagnostic for MEN1 ( 7 ). Lesions of the parathyroid gland, adenoma or hyperplasia are almost always benign. The syndrome that is inherited in an autosomal dominant fashion is due to

Open access

Filomena Cetani, Chiara Banti, Elena Pardi, Simona Borsari, Paolo Viacava, Paolo Miccoli, Liborio Torregrossa, Fulvio Basolo, Maria Rosa Pelizzo, Massimo Rugge, Gianmaria Pennelli, Guido Gasparri, Mauro Papotti, Marco Volante, Edda Vignali, Federica Saponaro and Claudio Marcocci

Immunohistochemical staining of parafibromin. (A) Normal parathyroid gland. The parathyroid cells show a diffuse nuclear immunoreactivity associated with a moderate cytoplasmatic staining (×200). (B) Normal parathyroid gland, negative control (omission of primary

Open access

Maria Angela D'amico, Barbara Ghinassi, Pascal Izzicupo, Lamberto Manzoli and A Di Baldassarre

hypocalcemia in the parathyroid gland (3) (in this context, it is also referred as parathyroid secretory protein 1). It represents the most abundant protein among the phosphorylated proteins released by the parathyroid glands and its secretion and