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rate in ovarian cancer patients is mostly due to a late diagnosis, at which time the cancer has metastasized throughout the peritoneal cavity and omentum ( 9 ). Epithelial ovarian cancer can disseminate via transcoelmic, hematogenous or lymphatic route
West Cancer Center, Memphis, Tennessee, USA
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West Cancer Center, Memphis, Tennessee, USA
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advances of hormone-dependent cancers focuses on three therapeutically challenging and scientifically fascinating cancers, viz. prostate, breast and ovarian cancers. These three cancers share several similarities and hence have been combined in this
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Introduction Ovarian cancer is the most lethal gynecological malignancy ( 1 , 2 ). Eighty-five to ninety percent of ovarian cancers are epithelial in nature. The main histological subtypes are serous, endometrioid, mucinous and clear cells
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Universidad La Salle, Posgrado de la Facultad de Ciencias Químicas, Ciudad de México, México
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Introduction According to statistics, ovarian cancer is the eighth leading cause of death by neoplasia in women worldwide ( 1 ). The most frequent type of ovarian tumor is epithelial ovarian cancer (EOC) ( 2 ). The EOC is further divided into
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Introduction Cancer survivors are living longer after the initial diagnosis of cancer due to earlier diagnosis and improved cancer treatments. Epithelial ovarian cancer (OC), uterine endometrial cancer (EC), and cervical cancer (CC) are major
Division of Endocrinology, Department of Medicine, Medstar Washington Hospital Center, Washington Hospital Center, Northwest, Washington, District of Columbia, USA
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renal toxicity associated with administration of platinum drugs in patients treated for ovarian cancers and radiation-induced salivary gland damage in patients with head and neck and lung cancers. The effects of amifostine on salivary gland function
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European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
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regulating growth, survival, differentiation and pathogen resistance ( 14 ). Constitutive activation of the STAT3 signalling pathway has been observed in several human cancers, including breast cancer, multiple myeloma, head and neck cancer, ovarian cancer
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Hematology Department, Fundeni Hospital, Bucharest, Romania
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Endocrine Department, Elias Hospital, Bucharest, Romania
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Patient population Endpoint Pro Lambertini, 2015 1231 BC POF, PR Shen, 2015 1062 BC POF, PR Del Mastro, 2014 765 BC, HL, ovarian cancer POF Sun, 2014 621 BC, HL, ovarian cancer POF Yang
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Chang-Claude J Moysich KB Rudolph A Schmutzler RK Simard J Soucy P Eeles RA Easton DF Hamann U Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers . Cancer Epidemiology
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malignancies of the ovary account for less than 10% of all ovarian cancers (germ cell tumors: 5%; sex cord stromal tumors: 3–5%) ( 1 ). Less than half of these nonepithelial tumors secrete hormones which can produce either estrogenic or androgenic