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Lu Liu, Chunyan Li, Peng Yang, Jian Zhu, Dongmei Gan, Le Bu, Manna Zhang, Chunjun Sheng, Hong Li and Shen Qu

Introduction Osteoporosis is a major metabolic bone disease that affects 44 million Americans or 55% of the population at the age of 50 years or older. Out of them, ten million individuals already have the disease while 34 million more are at an

Open access

Petar Milovanovic and Björn Busse

). (Backscattered electron microscopy images, Scale bar 1 µm). Our backscattered electron microscopy data on femoral cortical bone in young females, healthy aged females, females with untreated osteoporosis, and females with bisphosphonate-treated (BP

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Sylvia Thiele, Anke Hannemann, Maria Winzer, Ulrike Baschant, Heike Weidner, Matthias Nauck, Rajesh V Thakker, Martin Bornhäuser, Lorenz C Hofbauer and Martina Rauner

glucocorticoid-induced osteoporosis (GIO) involves many organ systems. At the skeletal level, GCs stimulate osteoclastogenesis and profoundly inhibit bone formation ( 3 , 4 ). While an increased receptor activator of NF-κB ligand (RANKL)/osteoprotegerin (OPG

Open access

Athanasios D Anastasilakis, Marina Tsoli, Gregory Kaltsas and Polyzois Makras

age range. All patients over 50 years of age had osteopenia or osteoporosis, whereas patients with active disease have lower BMD compared to controls and patients with inactive disease ( 38 ). Although the radiographic appearance of LCH lesions is

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Veronica Kieffer, Kate Davies, Christine Gibson, Morag Middleton, Jean Munday, Shashana Shalet, Lisa Shepherd and Phillip Yeoh

Adult Endocrine Nursing was published (4) . Subsequently, four new competencies – benign adrenal tumours, hypo- and hyperparathyroidism, osteoporosis and polycystic ovary syndrome – have been added to this second edition. These competencies build on the

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Keina Nishio, Akiko Tanabe, Risa Maruoka, Kiyoko Nakamura, Masaaki Takai, Tatsuharu Sekijima, Satoshi Tunetoh, Yoshito Terai and Masahide Ohmichi

) . Osteoporosis is common in women with breast cancer who receive chemotherapy, hormone therapy, or surgical castration, because these treatments induce bone loss (8) . Atkinson et al . (9) reported that prepubertal children with lymphoblastic leukemia who

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Emmanuelle Noirrit, Mélissa Buscato, Marion Dupuis, Bernard Payrastre, Coralie Fontaine, Jean-François Arnal and Marie-Cécile Valera

. Discussion CE conjugated with BZA is approved for the treatment of osteoporosis and vasomotor symptoms in postmenopausal non-hysterectomized women ( 23 ). This combination of estrogen and SERM presents a tissue-specific action, which has been investigated

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Karoline Winckler, Lise Tarnow, Louise Lundby-Christensen, Thomas P Almdal, Niels Wiinberg, Pia Eiken, Trine W Boesgaard and the CIMT trial group

defined as T -score below −1 but above −2.5, and osteoporosis was defined as any T -score ≤−2.5 (29) . Lumbar spine TBS was derived for each spine DXA examination via TBS Software (TBS iNsight Software, version 1.8; Med-Imaps, Pessac, France) installed

Open access

Kathrin R Frey, Tina Kienitz, Julia Schulz, Manfred Ventz, Kathrin Zopf and Marcus Quinkler

of GCs in PAI and CAH still tends to be more than the total daily endogenous cortisol secretion seen in healthy subjects (5–10 mg of cortisol/m 2 of body surface area/day) ( 1 ) possibly triggering long-term morbidities such as osteoporosis. GC

Open access

Elena Valassi, Natalia García-Giralt, Jorge Malouf, Iris Crespo, Jaume Llauger, Adolfo Díez-Pérez and Susan M Webb

vesicle-free lipoprotein ( 12 ). As a result, miRNAs have been advocated as promising biomarkers to predict onset and progression of chronic disease, including osteoporosis ( 13 ). Different levels of circulating miRNAs (‘signatures’) have been found in