Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Endocrinology, Sahlgrenska University Hospital, Gothenburg, Sweden
Wallenberg Center for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden
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Introduction Oral glucocorticoid (GC) treatment can lead to adrenal insufficiency by suppressing the hypothalamic–pituitary–adrenal axis. This can result in life-threatening adrenal crisis if the patient does not receive an increased GC dose
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a mechanistic link between glucocorticoid excess and visceral adiposity is the normalisation of fat distribution following successful treatment of Cushing’s syndrome ( 20 ). Exogenous oral glucocorticoids and their effects on tendon Numerous
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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suddenly stopped Failure to observe Sick Day Rule 1 : the need to double daily oral glucocorticoid dose during intercurrent illness with fever that requires bed rest and/or antibiotics Failure to observe Sick Day Rule 2 : the need to administer
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of the oral vs i.v. glucocorticoids. Parameters Oral glucocorticoid ( n = 92) i.v. glucocorticoid ( n = 61) Overall response (complete/partial) Clinical 47/60 (78.3) 34/37 (91.9) Hormonal 30/66 (45
Department of Medicine-Western Health, Australian Institute for Musculoskeletal Science (AIMSS), Melbourne Medical School, The University of Melbourne, Melbourne, Victoria, Australia
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Institute for Physical Activity and Nutrition, Deakin University, Geelong, Victoria, Australia
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Department of Medicine-Western Health, Australian Institute for Musculoskeletal Science (AIMSS), Melbourne Medical School, The University of Melbourne, Melbourne, Victoria, Australia
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.082401.104914 ) 10.1146/annurev.immunol.20.082401.104914 11861600 3 Fardet L Petersen I Nazareth I. [Description of oral glucocorticoid prescriptions in general population] . La Revue de Medecine Interne 2011 32 594 – 599 . ( https://doi.org/10.1016/j
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Journal of Medicine 1993 95 258 – 264 . ( https://doi.org/10.1016/0002-9343(9390277-v ) 12 Movahedi M Costello R Lunt M Pye SR Sergeant JC & Dixon WG . Oral glucocorticoid therapy and all-cause and cause-specific mortality in patients with
Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK
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Department of Endocrinology, University of Manchester, School of Medical Sciences, Manchester, UK
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excess is defined by 3 or more units of alcohol daily; glucocorticoid use includes current exposure to oral glucocorticoids or previous exposure for more than 3 months at a dose of prednisolone of 5 mg daily or more; current (but not previous) tobacco
Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
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Department of Endocrinology, Imperial College Healthcare NHS Trust, London, UK
Department of Clinical Biochemistry, North West London Pathology, London, UK
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flexibility and greater convenience for patients and clinicians in the outpatient setting. For many years, individuals with AI have received over-replacement with oral glucocorticoids ( 19 , 20 ). With higher doses of prednisolone, symptoms may be
Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China
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Department of Neurosurgery, 900th Hospital, Fuzhou, China
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postoperatively. Preoperative routine examination of the hypothalamus–pituitary–adrenal (HPA) axis and hypothalamus–pituitary–thyroid (HPT) axis functions was performed to determine the low function and the need for oral glucocorticoid and thyroxine replacement
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St.Anna Kinderspital, Medical University of Vienna, Vienna, Austria
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of adrenal androgen production ( 5 ). Oral glucocorticoid regimens aim to roughly mimic the physiological diurnal pattern but allow the ACTH suppression to escape in-between doses ( 6 ). There are numerous reviews and guidelines available for the