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prediabetes and new-onset diabetes. As a basic characteristic of type 2 diabetes mellitus (T2DM), insulin resistance plays an important role in the development and progression of arteriosclerosis. Insulin resistance is present in prediabetes, and populations
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from several studies suggests that individuals with AP are at a two-times increased risk of new-onset diabetes than the general population, independent of the severity of AP ( 5 , 6 , 7 ). Given that the cumulative incidence of new-onset diabetes
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Rani CS Jeba Rani S Gupta R Jha A Gupta V Kuchay MS Luthra A Durrani S et al . Glycemic parameters in patients with new-onset diabetes during COVID-19 pandemic are more severe than in patients with new-onset diabetes before the pandemic
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in patients with type 2 diabetes ( 8 ). Regarding individual statins, simvastatin or rosuvastatin use was associated with the highest risk for type 2 diabetes, whereas pravastatin use was associated with low risk of new-onset diabetes ( 9 ). Statins
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-analysis . Diabetes Care 2009 32 1924 – 1929 . ( doi:10.2337/dbib9-0738 ) 19794004 10.2337/dc09-0738 5 Waters DD Ho JE DeMicco DA Breazna A Arsenault BJ Wun CC Kastelein JJ Colhoun H Barter P. Predictors of new-onset
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Garvan Institute of Medical Research, New South Wales, Australia
School of Medical Sciences, University of New South Wales, New South Wales, Australia
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Department of Diabetes and Endocrinology, Blacktown Hospital, New South Wales, Australia
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Endocrine Research Unit, Department of Endocrinology, Odense University Hospital & Department of Clinical Research, Faculty of Health, University of Southern Denmark, Odense, Denmark
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controls ( 3 ). Insulin resistance is increased by more than 30% as early as 3 months after the initiation of ADT ( 4 ), and the risk of new-onset diabetes is increased four- to five-fold in the first year of treatment ( 5 ). These conditions are known to
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) Usually 1–3 months after treatment Hyperglycaemia and new-onset diabetes Approximately 1% (59) Anti-PD-1/PD-L1 (58, 61, 62) Polydipsia, polyuria, weight loss Hyperglycaemia on fasting and random glucose samples, HbA1c Persistent
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non-obese adults with new-onset diabetes? European Journal of Endocrinology 2014 170 651 – 658 . ( https://doi.org/10.1530/EJE-13-0901 ) 26 Gu Y Zhang M Chen H Wang Z Xing C Yang H Xu X Liu Y Zhou Z Yu L Discordant
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Department of Internal Medicine, Section of Metabolic Vascular Medicine, Division of Diabetes and Nutritional Sciences, Cardiovascular Endocrinology Laboratory, Faculty of Medicine, Hospital de Urgencias, National University of Córdoba, X5000 Córdoba, Argentina
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higher probability of insulin resistance in lean and obese individuals (76) . Moreover, in the latter study low cNP concentrations are predictive of new-onset diabetes (123) . Together, these data suggest that a cNP deficit, as observed in obese
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. Emerging Infectious Diseases 2020 26 1618 – 1620 . ( https://doi.org/10.3201/eid2607.200445 ) 38 Rubino F Amiel SA Zimmet P Alberti G Bornstein S Eckel RH Mingrone G Boehm B Cooper ME Chai Z New-onset diabetes in Covid-19 . New