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Ashley K Clift, Oskar Kornasiewicz, Panagiotis Drymousis, Omar Faiz, Harpreet S Wasan, James M Kinross, Thomas Cecil and Andrea Frilling

Introduction Initially termed ‘goblet cell carcinoids’ ( 1 ), goblet cell carcinomas (GCC) are a rare sub-type of neoplasm arising from the appendix, accounting for less than 14% of all appendiceal tumours ( 2 ). Whilst an ‘intermediate

Open access

Kosmas Daskalakis, Marina Tsoli, Anna Angelousi, Evanthia Kassi, Krystallenia I Alexandraki, Denise Kolomodi, Gregory Kaltsas and Anna Koumarianou

Introduction Neuroendocrine neoplasms (NENs) represent a heterogeneous group of tumours with variable clinical behaviour and unpredictable prognosis. Their incidence has increased substantially in recent years, partly due to the development of

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Klaudia Zajkowska, Janusz Kopczyński, Stanisław Góźdź and Aldona Kowalska

results and literature review, the authors proposed that the name ‘noninvasive encapsulated FVPTC’ be replaced with the term ‘noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)’ to emphasise the indolent course of the

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Linfei Yang, Xiao Yu and Yongchao Yang

Introduction The incidence of pancreatic neuroendocrine neoplasm (pNEN), the most aggressive neuroendocrine malignancy among gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs), has increased significantly over the past few decades

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Xu Han, Xuefeng Xu, Hongyun Ma, Yuan Ji, Dansong Wang, Tiantao Kuang, Wenchuan Wu, Bin Song, Gang Li, Gang Jin and Wenhui Lou

Introduction Pancreatic neuroendocrine neoplasms (pNENs) are rare and heterogeneous neoplasms of the pancreas, which make up 1–5% of all pancreatic neoplasms ( 1 , 2 ). The incidence and prevalence of pNENs have been increasing significantly

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Wentao Zhou, Tiantao Kuang, Xu Han, Wenqi Chen, Xuefeng Xu, Wenhui Lou and Dansong Wang

Introduction Pancreatic neuroendocrine neoplasm (pNEN) is a rare malignancy arising from pancreatic islet cells and accounts for 1–2% of all pancreatic tumors ( 1 ). However, with the popularization of abdominal imaging and the promotion of

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Simon Schimmack, Yongchao Yang, Klaus Felix, Markus Herbst, Yixiong Li, Miriam Schenk, Frank Bergmann, Thilo Hackert and Oliver Strobel

Introduction Pancreatic neuroendocrine neoplasm (pNEN), the most aggressive neuroendocrine malignancy, has an increasing incidence, with 3.2 cases per 1,000,000 inhabitants currently being diagnosed annually in the United States ( 1 , 2 , 3

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Sara Storvall, Helena Leijon, Eeva Ryhänen, Johanna Louhimo, Caj Haglund, Camilla Schalin-Jäntti and Johanna Arola

neoplasms. They not only suppress hormonal hypersecretion by binding to different SSTs, but also have an antiproliferative effect on tumor cells ( 20 ). The somatostatin analog octreotide as well as peptide receptor-based radiotherapy, both of which

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Dong Cen, Hui Liu, Zhe Wan, Zhongjie Lin, Yanting Wang, Junjie Xu and Yuelong Liang

Introduction Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors that are derived from diffuse neuroendocrine cells. As a result of improved detection of early-stage disease and possibly stage migration, the incidence and

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Filippo Ceccato, Diego Cecchin, Michele Gregianin, Giacomo Ricci, Cristina Campi, Filippo Crimì, Marta Bergamo, Annibale Versari, Carmelo Lacognata, Federico Rea, Mattia Barbot and Carla Scaroni

-pituitary neoplasm (ectopic ACTH secretion, EAS) ( 1 , 2 , 3 , 4 ). Achieving the goals of CS treatment (to normalize cortisol levels, to reverse the clinical symptoms and to remove the secreting neoplasm) is a challenge, especially in EAS ( 5 , 6 ). EAS is