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Michael J Gratz, Stavroula Stavrou, Christina Kuhn, Simone Hofmann, Kerstin Hermelink, Helene Heidegger, Stefan Hutter, Doris Mayr, Sven Mahner, Udo Jeschke and Aurelia Vattai

their structure. TAs affect dopamine signalling through TAAR1 and D2R heteromers ( 3 ). In a recent study, we found an increase of TAAR1 levels in placental tissue of patients with spontaneous miscarriages (SMs) and recurrent miscarriages (RMs). We

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Kusum Lata, Pinaki Dutta, Subbiah Sridhar, Minakshi Rohilla, Anand Srinivasan, G R V Prashad, Viral N Shah and Anil Bhansali

Introduction Miscarriage is the spontaneous loss of the conceptus before 20 weeks of gestation. Potential amount of possible miscarriage before pregnancy is recognised to be about 30%. In clinically recognised pregnancy, it is 10–15% before 8th week

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Jiashu Li, Aihua Liu, Haixia Liu, Chenyan Li, Weiwei Wang, Cheng Han, Xinyi Wang, Yuanyuan Zhang, Weiping Teng and Zhongyan Shan

-eclampsia and an increased risk of perinatal mortality, but not with miscarriage ( 7 ). However, recent studies have reported that SCH during pregnancy was associated with miscarriage ( 8 , 9 , 10 , 11 ), and higher maternal TSH levels have been detected in

Open access

Stavroula Stavrou, Michael Gratz, Eileen Tremmel, Christina Kuhn, Simone Hofmann, Helene Heidegger, Mina Peryanova, Kerstin Hermelink, Stefan Hutter, Bettina Toth, Doris Mayr, Sven Mahner, Udo Jeschke and Aurelia Vattai

Introduction Thyroid disorders such as hypothyroidism and hyperthyroidism are associated with increased miscarriage and stillbirth rates ( 1 ). Untreated hypothyroidism can result in a twofold increase of miscarriages; therefore, the

Open access

Yao Ye, Aurelia Vattai, Nina Ditsch, Christina Kuhn, Martina Rahmeh, Sven Mahner, Myriam Ripphahn, Roland Immler, Markus Sperandio, Udo Jeschke and Viktoria von Schönfeldt

the placenta of spontaneous miscarried and RPL patients ( 16 , 17 , 18 , 19 , 20 , 21 ). However, little is known about the expression of membrane receptors of PGE 2 in the placenta of women with uRPL. The effects of PGE 2 are mainly facilitated

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Ling Shan, Yingying Zhou, Shiqiao Peng, Xinyi Wang, Zhongyan Shan and Weiping Teng

antibody are associated with a higher rate of spontaneous pregnancy loss as compared with women with TSH levels lower than 2.5 mIU/L ( 5 ). However, the mechanisms underlying miscarriage caused by SCH are still unclear. Leukemia inhibitory factor (LIF) is

Open access

Neil R Chappell, Beth Zhou, Amy K Schutt, William E Gibbons and Chellakkan S Blesson

preeclampsia, gestational diabetes, preterm delivery and higher infant mortality ( 2 ). PCOS patients have higher miscarriage rates ( 3 , 4 ), higher risk of ovarian hyperstimulation (OHSS) and increased risks in offspring born after assisted reproduction

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Rui-yi Tang, Rong Chen, Miao Ma, Shou-qing Lin, Yi-wen Zhang and Ya-ping Wang

gestational diabetes mellitus ( n  = 1) and premature delivery at 36 weeks ( n  = 1). The other 2 women experienced first-trimester miscarriages after IVF-ET. Figure 3 Fertility outcomes among 106 patients with IHH. Twenty-four women who were planning a

Open access

Aaron Lerner, Patricia Jeremias and Torsten Matthias

Depression, anxiety Depression Anxiety, nervousness, restlessness, attention and concentrating difficulties Hair loss + + +/− Alopecia Infertility/missed periods +/+ +/+ +/+ Miscarriage + + + Increased other

Open access

Raymond J Rodgers, Jodie C Avery, Vivienne M Moore, Michael J Davies, Ricardo Azziz, Elisabet Stener-Victorin, Lisa J Moran, Sarah A Robertson, Nigel K Stepto, Robert J Norman and Helena J Teede

, central adiposity), reproductive dysfunction (infertility, menstrual irregularity, miscarriage, pregnancy complications) and metabolic complications ( 6 , 7 ). Metabolic features include insulin resistance (IR), compensatory hyperinsulinaemia and