Department of Science and Environment, Roskilde University, Roskilde, Denmark
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Department of Clinical Immunology, Næstved Hospital, Næstved, Denmark
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well as many different miRNAs. Some of these miRNAs (e.g. miR-122, miR-223) are believed to have a more pronounced role than others, as several studies confirm their associations ( 15 , 16 ). miRNAs are produced in cells of various tissues and serve as
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Division of Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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Division of Auxology, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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Division of Metabolic Diseases, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
Division of Auxology, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy
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10% top expressed circulating miRNome with a log2 fold change (FC) greater than 5 (Supplementary Table 4). Among the highly expressed miRNA in serum, miR-92a-3p, mir-122, miR-185-5p, 191-5p were implicated in lipid metabolism and their association
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.006 −1.88 ± 0.008 −1.2 0.17 0.35 hsa-miR-324-5p −0.44 ± 0.008 −4.77 ± 0.008 1.23 0.17 0.35 hsa-miR-29a-3p −2.65 ± 0.006 −2.43 ± 0.007 −1.16 0.23 0.43 hsa-miR-122-5p −1.88 ± 1.02 −0.15 ± 0.13 −0.12 0
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.127274 ) 45 Li M Tang Y Wu L Mo F Wang X Li H Qi R Zhang H Srivastava A Ling C The hepatocyte-specific HNF4α/miR-122 pathway contributes to iron overload-mediated hepatic inflammation . Blood 2017 130 1041 – 1051 . ( https