Filter

Refine by collections

Refine by date

—
  • Print
  • Save

Search Results

You are looking at 1 - 10 of 230 items for :

  • "metabolites" x
Clear All
Britt J van Keulen Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

Search for other papers by Britt J van Keulen in
Google Scholar
PubMed Close
,
Michelle Romijn Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

Search for other papers by Michelle Romijn in
Google Scholar
PubMed Close
,
Bibian van der Voorn Department of Pediatric Endocrinology, Sophia Kinderziekenhuis, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

Search for other papers by Bibian van der Voorn in
Google Scholar
PubMed Close
,
Marita de Waard Emma Children’s Hospital, Amsterdam University Medical Centers, locations AMC and VUmc, Amsterdam, The Netherlands

Search for other papers by Marita de Waard in
Google Scholar
PubMed Close
,
Michaela F Hartmann Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University, Giessen, Germany

Search for other papers by Michaela F Hartmann in
Google Scholar
PubMed Close
,
Johannes B van Goudoever Emma Children’s Hospital, Amsterdam University Medical Centers, locations AMC and VUmc, Amsterdam, The Netherlands

Search for other papers by Johannes B van Goudoever in
Google Scholar
PubMed Close
,
Stefan A Wudy Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University, Giessen, Germany

Search for other papers by Stefan A Wudy in
Google Scholar
PubMed Close
,
Joost Rotteveel Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands

Search for other papers by Joost Rotteveel in
Google Scholar
PubMed Close
, and
Martijn J J Finken Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

Search for other papers by Martijn J J Finken in
Google Scholar
PubMed Close

arterial hypotension ( 13 ). We aimed to examine whether male and female preterm infants differ in cortisol production and metabolism as assessed by glucocorticoid metabolite excretion in urine, as a possible explanation for the sex differences in

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0587
Volume/Issue:
Volume 10: Issue 2
Open access
Britt J van Keulen Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

Search for other papers by Britt J van Keulen in
Google Scholar
PubMed Close
,
Conor V Dolan Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Search for other papers by Conor V Dolan in
Google Scholar
PubMed Close
,
Bibian van der Voorn Department of Pediatric Endocrinology, Sophia Kinderziekenhuis, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

Search for other papers by Bibian van der Voorn in
Google Scholar
PubMed Close
,
Ruth Andrew Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, UK

Search for other papers by Ruth Andrew in
Google Scholar
PubMed Close
,
Brian R Walker Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh, UK
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK

Search for other papers by Brian R Walker in
Google Scholar
PubMed Close
,
Hilleke Hulshoff Pol Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands

Search for other papers by Hilleke Hulshoff Pol in
Google Scholar
PubMed Close
,
Dorret I Boomsma Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands

Search for other papers by Dorret I Boomsma in
Google Scholar
PubMed Close
,
Joost Rotteveel Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

Search for other papers by Joost Rotteveel in
Google Scholar
PubMed Close
, and
Martijn J J Finken Emma Children’s Hospital, Amsterdam UMC, Vrije Universiteit Amsterdam, Pediatric Endocrinology, Amsterdam, The Netherlands

Search for other papers by Martijn J J Finken in
Google Scholar
PubMed Close

inactive metabolite cortisone. 11β-HSD type 1 is mainly expressed in the liver and adipose tissue, where it regenerates cortisol, and 11β-HSD type 2 catalyzes the reverse reaction in renal epithelial cells. Figure 1 Schematic overview of cortisol

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0123
Volume/Issue:
Volume 9: Issue 6
Open access
Xiaomin Li Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China

Search for other papers by Xiaomin Li in
Google Scholar
PubMed Close
,
Ling Fang Department of Breast Surgery, Cheng Du Shang Jin Nan Fu Hospital, West China Hospital, Sichuan University, Chengdu, China

Search for other papers by Ling Fang in
Google Scholar
PubMed Close
,
Hongjiang Li Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China

Search for other papers by Hongjiang Li in
Google Scholar
PubMed Close
, and
Xiaoqin Yang Department of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China

Search for other papers by Xiaoqin Yang in
Google Scholar
PubMed Close

, has gradually increased recently ( 1 , 2 ). In patients with breast cancer, abnormalities occur in estrogen metabolism, in particular in the level of estrogen and their metabolites. Hydroxylation of the carbon atoms at positions 2, 4, and 16 of the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0226
Volume/Issue:
Volume 10: Issue 12
Open access
J A Tamblyn Institute of Metabolism and Systems Research (IMSR), College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
Birmingham Women’s Foundation Hospital, Edgbaston, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

Search for other papers by J A Tamblyn in
Google Scholar
PubMed Close
,
C Jenkinson Birmingham Women’s Foundation Hospital, Edgbaston, Birmingham, UK

Search for other papers by C Jenkinson in
Google Scholar
PubMed Close
,
D P Larner Birmingham Women’s Foundation Hospital, Edgbaston, Birmingham, UK

Search for other papers by D P Larner in
Google Scholar
PubMed Close
,
M Hewison Institute of Metabolism and Systems Research (IMSR), College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

Search for other papers by M Hewison in
Google Scholar
PubMed Close
, and
M D Kilby Institute of Metabolism and Systems Research (IMSR), College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
Birmingham Women’s Foundation Hospital, Edgbaston, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

Search for other papers by M D Kilby in
Google Scholar
PubMed Close

causality ( 33 , 34 ). This heterogeneity reflects our limited understanding of the effects of vitamin D during pregnancy at the cellular level and suggests that measurement of serum 25(OH)D3 alone may be too simplistic. Other vitamin D metabolites such as

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0308
Volume/Issue:
Volume 7: Issue 1
Open access
Emmi Naskali Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

Search for other papers by Emmi Naskali in
Google Scholar
PubMed Close
,
Katja Dettmer Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

Search for other papers by Katja Dettmer in
Google Scholar
PubMed Close
,
Peter J Oefner Institute of Functional Genomics, University of Regensburg, Regensburg, Germany

Search for other papers by Peter J Oefner in
Google Scholar
PubMed Close
,
Pedro A B Pereira Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland

Search for other papers by Pedro A B Pereira in
Google Scholar
PubMed Close
,
Kai Krohn Clinical Research Institute HUCH Ltd, Biomedicum Helsinki 1, Helsinki, Finland

Search for other papers by Kai Krohn in
Google Scholar
PubMed Close
,
Petri Auvinen Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland

Search for other papers by Petri Auvinen in
Google Scholar
PubMed Close
,
Annamari Ranki Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

Search for other papers by Annamari Ranki in
Google Scholar
PubMed Close
, and
Nicolas Kluger Department of Dermatology, Allergology and Venereology, University of Helsinki, and Helsinki University Central Hospital, Helsinki, Finland

Search for other papers by Nicolas Kluger in
Google Scholar
PubMed Close

may directly influence the central nervous system function by controlling the production of neurotransmitters, such as 5-HT in the gut ( 15 ). In the present study, we assessed the serum levels of 5-HT, L-DOPA and Trp metabolites in our cohort of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0513
Volume/Issue:
Volume 8: Issue 1
Open access
Annieke C G van Baar Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands

Search for other papers by Annieke C G van Baar in
Google Scholar
PubMed Close
,
Andrei Prodan Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands

Search for other papers by Andrei Prodan in
Google Scholar
PubMed Close
,
Camilla D Wahlgren Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Camilla D Wahlgren in
Google Scholar
PubMed Close
,
Steen S Poulsen Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Steen S Poulsen in
Google Scholar
PubMed Close
,
Filip K Knop Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Filip K Knop in
Google Scholar
PubMed Close
,
Albert K Groen Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Department of Laboratory Medicine, University of Groningen, University Medical Center, Groningen, the Netherlands

Search for other papers by Albert K Groen in
Google Scholar
PubMed Close
,
Jacques J Bergman Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands

Search for other papers by Jacques J Bergman in
Google Scholar
PubMed Close
,
Max Nieuwdorp Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Department of Internal Medicine, VUMC Free University, Amsterdam, the Netherlands
Wallenberg Laboratory, Sahlgrenska Hospital, University of Gothenburg, Gothenburg, Sweden

Search for other papers by Max Nieuwdorp in
Google Scholar
PubMed Close
, and
Evgeni Levin Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Horaizon BV, Delft, the Netherlands

Search for other papers by Evgeni Levin in
Google Scholar
PubMed Close

is not clear whether and how the densities of L, K and D cells, respectively, are involved in the regulation of MetS features. In this cross-sectional study, we aimed to identify plasma metabolites that associate with duodenal L cell, K cell and D

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0094
Volume/Issue:
Volume 7: Issue 5
Open access
Shanlee M Davis Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA

Search for other papers by Shanlee M Davis in
Google Scholar
PubMed Close
,
Rhianna Urban Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA

Search for other papers by Rhianna Urban in
Google Scholar
PubMed Close
,
Angelo D’Alessandro Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA

Search for other papers by Angelo D’Alessandro in
Google Scholar
PubMed Close
,
Julie A Reisz Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, Colorado, USA

Search for other papers by Julie A Reisz in
Google Scholar
PubMed Close
,
Christine L Chan Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA

Search for other papers by Christine L Chan in
Google Scholar
PubMed Close
,
Megan Kelsey Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA

Search for other papers by Megan Kelsey in
Google Scholar
PubMed Close
,
Susan Howell Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA

Search for other papers by Susan Howell in
Google Scholar
PubMed Close
,
Nicole Tartaglia Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA

Search for other papers by Nicole Tartaglia in
Google Scholar
PubMed Close
,
Philip Zeitler Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA
eXtraOrdinarY Kids Clinic, Children's Hospital Colorado, Aurora, Colorado, USA

Search for other papers by Philip Zeitler in
Google Scholar
PubMed Close
, and
Peter Baker II Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA

Search for other papers by Peter Baker II in
Google Scholar
PubMed Close

testosterone-replacement therapy ( 8 ). Analysis of circulating levels of substrates and intermediate metabolites from intra-mitochondrial pathways, particularly β-oxidation of fatty acids, offers a non-invasive assessment of mitochondrial metabolism – a viable

Article Type:
Research Article
Collections:
Reproduction
DOI:
https://doi.org/10.1530/EC-22-0523
Volume/Issue:
Volume 12: Issue 5
Open access
Amalie Carlsson Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark

Search for other papers by Amalie Carlsson in
Google Scholar
PubMed Close
,
Kaspar Sørensen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
The Child and Youth Clinic, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

Search for other papers by Kaspar Sørensen in
Google Scholar
PubMed Close
,
Anna-Maria Andersson Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark

Search for other papers by Anna-Maria Andersson in
Google Scholar
PubMed Close
,
Hanne Frederiksen Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark

Search for other papers by Hanne Frederiksen in
Google Scholar
PubMed Close
, and
Anders Juul Department of Growth and Reproduction, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
International Research and Research Training Center in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen, Denmark

Search for other papers by Anders Juul in
Google Scholar
PubMed Close

, detectable measures of phthalate metabolites are still being found in 97% of the childhood population ( 1 ). The exposure to phthalates has been associated with increased risk of obesity in childhood, but data are equivocal ( 6 , 13 , 14 ). As for BPA

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0344
Volume/Issue:
Volume 7: Issue 1
Open access
Carlo Cinque Fondazione Ethoikos, Radicondoli, Italy
Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

Search for other papers by Carlo Cinque in
Google Scholar
PubMed Close
,
Manuela Zinni Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

Search for other papers by Manuela Zinni in
Google Scholar
PubMed Close
,
Anna Rita Zuena Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

Search for other papers by Anna Rita Zuena in
Google Scholar
PubMed Close
,
Chiara Giuli Fondazione Ethoikos, Radicondoli, Italy

Search for other papers by Chiara Giuli in
Google Scholar
PubMed Close
,
Sebastiano G Alemà Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

Search for other papers by Sebastiano G Alemà in
Google Scholar
PubMed Close
,
Assia Catalani Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

Search for other papers by Assia Catalani in
Google Scholar
PubMed Close
,
Paola Casolini Department of Physiology and Pharmacology V. Erspamer, Sapienza University of Rome, Rome, Italy

Search for other papers by Paola Casolini in
Google Scholar
PubMed Close
, and
Roberto Cozzolino Fondazione Ethoikos, Radicondoli, Italy

Search for other papers by Roberto Cozzolino in
Google Scholar
PubMed Close

metabolism. It is known that, in mice and rats, a high percentage of steroid metabolites are excreted via faeces in comparison with other matrices ( 1 , 6 , 8 ). Faeces provide an averaged measure of hormone levels related to a time window depending on

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0338
Volume/Issue:
Volume 7: Issue 2
Open access
L Ghataore Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK

Search for other papers by L Ghataore in
Google Scholar
PubMed Close
,
I Chakraborti Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK

Search for other papers by I Chakraborti in
Google Scholar
PubMed Close
,
S J Aylwin Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK

Search for other papers by S J Aylwin in
Google Scholar
PubMed Close
,
K-M Schulte Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK

Search for other papers by K-M Schulte in
Google Scholar
PubMed Close
,
D Dworakowska Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK
Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK

Search for other papers by D Dworakowska in
Google Scholar
PubMed Close
,
P Coskeran Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK

Search for other papers by P Coskeran in
Google Scholar
PubMed Close
, and
N F Taylor Departments of, Clinical Biochemistry, Medicine, Department of Endocrinology and Internal Medicine, King's College Hospital, London SE5 9RS, UK

Search for other papers by N F Taylor in
Google Scholar
PubMed Close

derived from cortisol. Figure 1 Metabolic chart showing generation of the major cortisol metabolites (boxed) in the human, together with the major changes brought about by mitotane. Crosses show pathways inhibited by mitotane and upward arrows show

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0028
Volume/Issue:
Volume 1: Issue 1
Open access