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Daiki Kobayashi, Nagato Kuriyama, Keita Hirano, Osamu Takahashi and Hiroshi Noto

Introduction Previous systematic reviews and meta-analyses have reported that diabetic patients have a higher risk of developing malignancies compared to nondiabetic patients ( 1 , 2 , 3 , 4 ). Based on these reports, diabetic patients may

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Kranti Khadilkar, Vijaya Sarathi, Rajeev Kasaliwal, Reshma Pandit, Manjunath Goroshi, Gaurav Malhotra, Abhay Dalvi, Ganesh Bakshi, Anil Bhansali, Rajesh Rajput, Vyankatesh Shivane, Anurag Lila, Tushar Bandgar and Nalini S Shah

-associated malignant PCC/PGL ( 3 ). Majority of the malignant PCCs/PGLs are initially diagnosed as benign tumours but subsequently present with widespread metastasis ( 9 ). Small series and case reports have tried to analyse the clinical predictors for malignancy and

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Keina Nishio, Akiko Tanabe, Risa Maruoka, Kiyoko Nakamura, Masaaki Takai, Tatsuharu Sekijima, Satoshi Tunetoh, Yoshito Terai and Masahide Ohmichi

gynecological malignancies. Patients with these diseases generally undergo surgery that includes a bilateral oophorectomy followed by the administration of platinum-based chemotherapy in OC and EC patients, or concurrent chemo-radiation therapy (CCRT) in CC

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Katerina Saltiki, Elli Anagnostou, George Simeakis, Sofia Kouki, Anastasia Angelopoulou, Leda Sarika, Alexandra Papathoma and Maria Alevizaki

Introduction Medullary thyroid carcinoma (MTC) accounts for 5–10% of all thyroid malignancies. About 25% of MTCs are familial (fMTC) and are described as multiple endocrine neoplasia syndromes: MEN2A (associated with pheochromocytoma and

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Philippe Thuillier, Nathalie Roudaut, Geneviève Crouzeix, Marie Cavarec, Philippe Robin, Ronan Abgral, Véronique Kerlan and Pierre-Yves Salaun

and dTI, respectively ( 4 ). Moreover, in another meta-analysis, malignancy rate of fTI was as high as 34.6% (IC 95% 29.3–40.2) ( 5 ). Only few studies proposed a prospective design to investigate prevalence and malignancy rate of fTI in FDG PET

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Wafaa M Rashed, Anas Saad, Muneer Al-Husseini, Ahmed Mahmoud Galal, Assem Mohamed Ismael, Ahmed M Al-Tayep, Ayman El Shafie, Mahmoud Ahmed Ali and Ahmad Samir Alfaar

Introduction The adrenal gland malignancies are extremely sporadic and heterogeneous. It represents 3.6% of endocrine glands cancers ( 1 ). Adrenal malignancies can be either primary adrenal tumors or secondary metastases, with metastases

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Kristine Zøylner Swan, Steen Joop Bonnema, Marie Louise Jespersen and Viveque Egsgaard Nielsen

ultrasonography (US) and fine-needle aspiration biopsy (FNAB) are very useful in the evaluation of thyroid nodules, the identification of malignancy remains a challenge. Several US characteristics have been found to be more prevalent in malignant compared with

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Konstantin Yakimchuk, Chandrashekar Bangalore Revanna, Dan Huang, Jose Inzunza and Sam Okret

considered as endocrine-related malignancies. In addition to the endogenous estrogenic ligands, estrogen signaling may be influenced by environmental synthetic or natural (dietary) xenoestrogens, so-called endocrine-disrupting chemicals (EDCs). An

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Logan Mills, Panagiotis Drymousis, Yogesh Vashist, Christoph Burdelski, Andreas Prachalias, Parthi Srinivasan, Krishna Menon, Corina Cotoi, Saboor Khan, Judith Cave, Thomas Armstrong, Martin O Weickert, Jakob Izbicki, Joerg Schrader, Andreja Frilling, John K Ramage and Raj Srirajaskanthan

is reported in up to 14% of cases ≤2 cm, but the impact of nodal involvement on future metastasis or overall survival is debated ( 15 , 16 , 17 , 18 , 19 ). The lack of validated, reliable predictors of malignancy, such as serum markers or

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Maria Cristina De Martino, Richard A Feelders, Claudia Pivonello, Chiara Simeoli, Fortuna Papa, Annamaria Colao, Rosario Pivonello and Leo J Hofland

), which have been approved for the treatment of different malignancy such as renal cell carcinoma and pancreatic neuroendocrine tumors ( 14 , 15 ). More recently some compounds which also target the mTORC2 complex have been proposed as anticancer