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Comprehensive Cancer Center Mainfranken, University of Wuerzburg, Wuerzburg, Germany
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Department of Pathology, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France
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Department of Digestive and Endocrine Surgery, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France
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Department of Digestive and Endocrine Surgery, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France
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Institute of Metabolism and System Research, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Department of Endocrinology, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France
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mutations, chromosome alteration and DNA methylation profile, or at the RNA level, including transcriptome and targeted gene expression profiles. Intratumor heterogeneity of somatic mutations has been reported in many cancer types ( 12 , 13 , 14 ). In a
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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Department of Pathology, University of California, San Francisco, California, USA
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Division of Hematology and Oncology, Department of Medicine, University of California, San Francisco, California, USA
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N Stewart A , et al . Intratumor heterogeneity and branched evolution revealed by multiregion sequencing . New England Journal of Medicine 2012 366 883 – 892 . ( https://doi.org/10.1056/NEJMoa1113205 )
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