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Fahim Ebrahimi Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of Basel Hospital, Basel, Switzerland
Department of Clinical Research, University of Basel Hospital, Basel, Switzerland

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Sandrine A Urwyler Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of Basel Hospital, Basel, Switzerland
Department of Clinical Research, University of Basel Hospital, Basel, Switzerland

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Philipp Schuetz Department of Clinical Research, University of Basel Hospital, Basel, Switzerland
Division of Endocrinology, Diabetes and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Beat Mueller Department of Clinical Research, University of Basel Hospital, Basel, Switzerland
Division of Endocrinology, Diabetes and Metabolism, University Department of Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Luca Bernasconi Department of Laboratory Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Peter Neyer Department of Laboratory Medicine, Kantonsspital Aarau, Aarau, Switzerland

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Marc Y Donath Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of Basel Hospital, Basel, Switzerland
Department of Clinical Research, University of Basel Hospital, Basel, Switzerland

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Mirjam Christ-Crain Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, University of Basel Hospital, Basel, Switzerland
Department of Clinical Research, University of Basel Hospital, Basel, Switzerland

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leads to an increased activity of the hypothalamus–pituitary–adrenal (HPA) axis with excess of glucocorticoids which are known to increase the risk for metabolic complications and cardiovascular mortality ( 6 ). Interleukin-1β (IL-1β) is known to

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0201
Volume/Issue:
Volume 8: Issue 6
Open access
Milica Popovic Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Department of Clinical Research, University of Basel and University Hospital Basel, Basel, Switzerland

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Fahim Ebrahimi Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Department of Clinical Research, University of Basel and University Hospital Basel, Basel, Switzerland

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Sandrine Andrea Urwyler Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Department of Clinical Research, University of Basel and University Hospital Basel, Basel, Switzerland

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Marc Yves Donath Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Department of Biomedicine, University of Basel, Basel, Switzerland

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Mirjam Christ-Crain Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Department of Clinical Research, University of Basel and University Hospital Basel, Basel, Switzerland

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, history of a severe infection within the previous 2 months or a current infection, severe comorbidities and pregnancy or breastfeeding. After the screening visit, all patients received three s.c. injections of the recombinant human interleukin-1-receptor

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0197
Volume/Issue:
Volume 9: Issue 7
Open access
Xuan Luo Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Tingting Zheng Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Chaoming Mao Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China
Institute of Oncology, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Xin Dong Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Xiao Mou Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Chengcheng Xu Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Qingyan Lu Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Baocui Liu Department of Nuclear Medicine, The Affiliated Hospital of Jiangsu University, Zhenjiang, China

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Shengjun Wang Department of Laboratory Immunology, Jiangsu University School of Medicine, Zhenjiang, China

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Yichuan Xiao Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, China

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. ( https://doi.org/10.3389/fimmu.2018.00096 ) 29434604 10.3389/fimmu.2018.00096 14 Diamant M Kayser L Rasmussen AK Bech K Feldt-Rassmussen U . Interleukin-6 production by thyroid epithelial cells. Enhancement by interleukin-1 . Autoimmunity

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-18-0019
Volume/Issue:
Volume 7: Issue 6
Open access
Ali Abbasi MRC Epidemiology Unit, Department of Epidemiology and Department of Internal Medicine, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Post Box 285, Cambridge CB2 0QQ, UK
MRC Epidemiology Unit, Department of Epidemiology and Department of Internal Medicine, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Post Box 285, Cambridge CB2 0QQ, UK

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2298850/ DBP GC , rs10741657/CYP2R1, rs3794060/NADSYN1, rs6013897/ CYP24A1 Null Vitamin D binding protein 1 (31) CaMos Canada/2014 201/2254 rs2282679/ DBP GC Null RR, relative risk; IL1-Ra, interleukin 1 receptor antagonist; DIAGRAM, DIAbetes Genetics

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0087
Volume/Issue:
Volume 4: Issue 4
Open access
Xiao Zong Department of Vascular & Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Qin Fan Department of Vascular & Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Hang Zhang Department of Vascular & Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Qian Yang Department of Vascular & Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Hongyang Xie Department of Vascular & Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Qiujing Chen Institution of Cardiovascular Diseases, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Ruiyan Zhang Department of Vascular & Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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Rong Tao Department of Vascular & Cardiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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adipose tissue can secrete various proinflammatory factors such as tumor necrosis factor-α, interleukin-6, and interleukin-1. Therefore, obesity itself is a state of inflammation, which may be reflected or influenced by sST2. Moreover, hypertension, DM

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0645
Volume/Issue:
Volume 10: Issue 3
Open access
Estíbaliz Castillero
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Ana Isabel Martín
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Maria Paz Nieto-Bona Department of Physiology, Department of Histology, Faculty of Medicine, Complutense University of Madrid, 28040 Madrid, Spain

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Carmen Fernández-Galaz
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María López-Menduiña
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María Ángeles Villanúa
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Asunción López-Calderón
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and destructive action of interleukin 1 β (IL1B) in human osteoarthritic cartilage samples (9) and in rabbit articular chondrocytes (10) . Our group has reported that chronic arthritis decreases Pparα expression in liver and gastrocnemius, whereas

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0003
Volume/Issue:
Volume 1: Issue 1
Open access
Ferdinand Roelfsema Department of Internal Medicine, Section Endocrinology, Leiden University Medical Center, Leiden, The Netherlands

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Peter Y Liu Department of Medicine, David Geffen School of Medicine at UCLA, Harbor-UCLA Medical Center and Los Angeles Biomedical Research Institute, Los Angeles, California, USA

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Rebecca Yang Endocrine Research Unit, Mayo Clinic College of Medicine, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota, USA

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Paul Takahashi Primary Care Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA

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Johannes D Veldhuis Endocrine Research Unit, Mayo Clinic College of Medicine, Center for Translational Science Activities, Mayo Clinic, Rochester, Minnesota, USA

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Physiology 1995 268 E813 – E819 . 36 Berkenbosch F van OJ del RA Tilders F Besedovsky H . Corticotropin-releasing factor-producing neurons in the rat activated by interleukin-1 . Science 1987 238 524 – 526 . ( https://doi.org/10

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0211
Volume/Issue:
Volume 9: Issue 7
Open access
Yao Chen Hangzhou Fuyang Women and Children Hospital, Hangzhou, China

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Shu-ying Fang Hangzhou Fuyang Women and Children Hospital, Hangzhou, China

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) C677T polymorphism, peroxisome proliferator-activated receptor gamma ( PPAR-γ ) polymorphism and interleukin-1beta/IL-1 receptor antagonist ( IL-1β/IL-1Ra ) gene polymorphisms. StAR polymorphisms Hyperandrogenism accounts for most of the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0121
Volume/Issue:
Volume 7: Issue 5
Open access
Anastasia K Armeni Division of Reproductive Endocrinology, Department of Obstetrics and Gynaecology, University of Patras Medical School, Patras, Greece

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Konstantinos Assimakopoulos Department of Psychiatry, University of Patras Medical School, Patras, Greece

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Dimitra Marioli Division of Reproductive Endocrinology, Department of Obstetrics and Gynaecology, University of Patras Medical School, Patras, Greece

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Vassiliki Koika Division of Reproductive Endocrinology, Department of Obstetrics and Gynaecology, University of Patras Medical School, Patras, Greece

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Euthychia Michaelidou Department of Biology, University of Patras, Patras, Greece

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Niki Mourtzi Department of Biology, University of Patras, Patras, Greece

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Gregoris Iconomou Department of Psychiatry, University of Patras Medical School, Patras, Greece

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Neoklis A Georgopoulos Division of Reproductive Endocrinology, Department of Obstetrics and Gynaecology, University of Patras Medical School, Patras, Greece

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women ( 57 ). A further study reported an association between the dopamine D4 receptor gene ( DRD4 ) with self-reports of sexual desire and arousal in 52 men and 92 women ( 58 ). Interleukin-1beta gene ( IL1B ) has been correlated with variation in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-16-0090
Volume/Issue:
Volume 6: Issue 1
Open access
Antonina Khoruzhenko Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium
Institute of Molecular Biology and Genetics, NAS of Ukraine, Kiev, Ukraine

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Françoise Miot Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium

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Claude Massart Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium

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Jacqueline Van Sande Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium

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Jacques Emile Dumont Institute of Interdisciplinary Research (IRIBHM), Université libre de Bruxelles, Brussels, Belgium

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Renaud Beauwens Laboratory of Physiology and Pharmacology, Université libre de Bruxelles, Brussels, Belgium

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Alain Boom Laboratoire d’Histologie, de Neuroanatomie et de Neuropathologie, Université libre de Bruxelles, Brussels, Belgium

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-presenting dendritic cells as regulators of the growth of thyrocytes: a role of interleukin-1β and interleukin-6 . Endocrinology 1998 139 3148 – 3156 . ( https://doi.org/10.1210/endo.139.7.6110 ) 15 Herzog V Miller F Membrane retrieval in epithelial cells

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0169
Volume/Issue:
Volume 10: Issue 5
Open access