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crucial to mitigate associated disabilities and fatalities ( 5 ). Insulin resistance (IR) is a central factor in cardiovascular diseases ( 6 ). In hypertensive patients, IR not only exacerbates hypertension but also contributes to hypertension
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Division of Endocrinology and Metabolism, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Division of Endocrinology and Metabolism, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Cardiovascular Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
Taipei Heart Institute, Taipei Medical University, Taipei, Taiwan
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removal from the circulation and consequently hyperlipidemia ( 40 ). Accordingly, vitamin D may reduce serum lipids through inhibiting parathyroid hormone secretion. Moreover, vitamin D deficiency was shown to increase the risk of insulin resistance, which
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development ( 24 , 25 , 26 ). As the main apolipoprotein in chylomicrons and LDL, APOA4 is related to lipid metabolism, insulin resistance, and oxidative stress ( 27 , 28 , 29 ). FTCD plays an important role in inducing the production of ROS, mitochondrial
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Department of Cardiology, Yanbian University Hospital, Yanji, China
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. ( https://doi.org/10.1161/JAHA.122.026586 ) 51 Qin Y Chen M Yang Y Zhou XR Shao SY Wang DW & Yuan G . Liraglutide improves hepatic insulin resistance via the canonical Wnt signaling pathway . Molecular Medicine Reports 2018 17 7372 – 7380
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Introduction Adult growth hormone deficiency (AGHD) is associated with increased visceral adiposity, insulin resistance, dyslipidaemia and hyperglycaemia ( 1 ). AGHD may persist from childhood or be acquired in adulthood as a result of