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Dirk Weismann Department of Internal Medicine I, Intensivcare Unit, University Hospital of Würzburg, Würzburg, Germany

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Andreas Schneider Department of Internal Medicine I, Intensivcare Unit, University Hospital of Würzburg, Würzburg, Germany

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Charlotte Höybye Department of Endocrinology, Metabolism and Diabetology, Karolinska University Hospital, Stockholm, Sweden
Department of Molecular Surgery and Medicine, Karolinska Institute, Stockholm, Sweden

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Introduction Hyponatremia (HN) is the most common electrolyte disturbance in hospitalized patients constituting at least about 30% of patients in medical, surgical and psychiatric wards ( 1 , 2 ). The syndrome of inappropriate antidiuresis

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-16-0046
Volume/Issue:
Volume 5: Issue 5
Open access
Kunzhe Lin Department of Neurosurgery, Affiliated Fuzhou First Hospital of Fujian Medical University, Fuzhou, China
Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China

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Lingling Lu Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China

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Zhijie Pei Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China

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Shuwen Mu Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China

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Shaokuan Huang Department of Neurosurgery, Guiqian International General Hospital, Guiyang, China

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Shousen Wang Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, China
Department of Neurosurgery, 900th Hospital, Fuzhou, China

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Introduction Delayed hyponatremia refers to hyponatremia that occurs ≥3 days after transsphenoidal surgery (TSS) ( 1 ). Patients with hyponatremia may have various clinical manifestations, ranging from asymptomatic to mild (headache, nausea

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-21-0497
Volume/Issue:
Volume 11: Issue 1
Open access
Jorge Gabriel Ruiz-Sánchez Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD, UAM), Hospital Universitario Fundación Jiménez Díaz, Madrid, España
Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España

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Alfonso Luis Calle-Pascual Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España
Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Madrid, España

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Miguel Ángel Rubio-Herrera Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España

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María Paz De Miguel Novoa Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España

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Emilia Gómez-Hoyos Servicio de Endocrinología y Nutrición, Hospital Clínico Universitario de Valladolid, Valladolid, España

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Isabelle Runkle Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España
Servicio de Endocrinología y Nutrición. Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Hospital Clínico San Carlos, Madrid, España

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considered to be its sole electrolytic manifestation. However, prior series ( 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 ), including the first case reported by Hudson et al. ( 23 ), detected the presence of hyponatremia

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-23-0430
Volume/Issue:
Volume 13: Issue 3
Open access
Amit Kumar Department of Medicine, Christian Medical College and Hospital, Ludhiana, Punjab, India

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Maria Ghosh Department of Biochemistry, Christian Medical College and Hospital, Ludhiana, Punjab, India

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Jubbin Jagan Jacob Department of Endocrinology, Christian Medical College and Hospital, Ludhiana, Punjab, India

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Introduction Two percent of community-dwelling adults in America have hyponatremia. These rates are more than double among adults over the age of 71 years ( 1 ). In hospitalized patients, the prevalence of hyponatremia is between 15 and 20

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0500
Volume/Issue:
Volume 10: Issue 12
Open access
Marianna Martino Division of Endocrinology and Metabolic Diseases, Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, Ancona, Italy

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Paolo Falcioni Division of Endocrinology and Metabolic Diseases, Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, Ancona, Italy

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Giulia Giancola Division of Endocrinology and Metabolic Diseases, Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, Ancona, Italy

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Alessandro Ciarloni Division of Endocrinology and Metabolic Diseases, Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, Ancona, Italy

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Gianmaria Salvio Division of Endocrinology and Metabolic Diseases, Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, Ancona, Italy

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Francesca Silvetti Division of Endocrinology and Metabolic Diseases, Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, Ancona, Italy

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Augusto Taccaliti Division of Endocrinology and Metabolic Diseases, Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, Ancona, Italy

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Giorgio Arnaldi Division of Endocrinology and Metabolic Diseases, Department of Clinical and Molecular Sciences (DISCLIMO), Polytechnic University of Marche, Ancona, Italy

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Introduction Hyponatremia (serum sodium concentration < 135 mmol/L) is the most common disorder of water balance in hospitalized patients, with a reported prevalence of 30% and a negative prognostic impact in the elderly, as well as in

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0411
Volume/Issue:
Volume 10: Issue 10
Open access
Cihan Atila Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Department of Clinical Research, University of Basel, Basel, Switzerland

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Sophie Monnerat Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Department of Clinical Research, University of Basel, Basel, Switzerland

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Roland Bingisser Emergency Department, University Hospital Basel, Basel, Switzerland

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Martin Siegemund Department of Intensive Care, University Hospital Basel, Basel, Switzerland

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Maurin Lampart Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland

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Marco Rueegg Emergency Department, University Hospital Basel, Basel, Switzerland

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Núria Zellweger Department of Intensive Care, University Hospital Basel, Basel, Switzerland

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Stefan Osswald Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland

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Katharina Rentsch Department of Laboratory Medicine, University Hospital Basel, Basel, Switzerland

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Mirjam Christ-Crain Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland
Department of Clinical Research, University of Basel, Basel, Switzerland

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Raphael Twerenbold Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, University of Basel, Basel, Switzerland
University Center of Cardiovascular Science & Department of Cardiology, University Heart and Vascular Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
German Center for Cardiovascular Research (DZHK), Partner Site Hamburg–Kiel–Lübeck, Hamburg, Germany

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Background Hyponatremia, defined as a plasma sodium concentration < 135 mmol/L, is the most common electrolyte disorder in both in- and outpatient settings ( 1 ). It is indicative of disturbed water homeostasis that can occur secondary to a

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0171
Volume/Issue:
Volume 11: Issue 10
Open access
Bettina Winzeler Department of Endocrinology, Diabetology and Metabolismus, University Hospital Basel, Basel, Switzerland
Department Clinical Research, University of Basel, Basel, Switzerland

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Michelle Steinmetz Department of Endocrinology, Diabetology and Metabolismus, University Hospital Basel, Basel, Switzerland
Department Clinical Research, University of Basel, Basel, Switzerland

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Julie Refardt Department of Endocrinology, Diabetology and Metabolismus, University Hospital Basel, Basel, Switzerland
Department Clinical Research, University of Basel, Basel, Switzerland

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Nicole Cesana-Nigro Department of Endocrinology and Diabetology, Bürgerspital Solothurn, Solothurn, Switzerland

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Milica Popovic Department of Endocrinology, Diabetology and Metabolismus, University Hospital Basel, Basel, Switzerland
Department Clinical Research, University of Basel, Basel, Switzerland

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Wiebke Fenske Department of Endocrinology and Nephrology, University of Leipzig, Leipzig, Germany
Leipzig University Medical Center, IFB Adiposity Diseases, Leipzig, Germany

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Mirjam Christ-Crain Department of Endocrinology, Diabetology and Metabolismus, University Hospital Basel, Basel, Switzerland
Department Clinical Research, University of Basel, Basel, Switzerland

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Introduction Hyponatremia is the most common electrolyte disturbance in hospitalized patients (15–30%) ( 1 ) and is associated with increased morbidity and mortality ( 2 , 3 ). One of its main causes is the syndrome of inappropriate

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0431
Volume/Issue:
Volume 9: Issue 1
Open access
Anna Sjöström Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Department of Clinical Chemistry, Karolinska University Hospital, Stockholm, Sweden

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Susanne Rysz Function Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden
Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden

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Henrik Sjöström Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Center for Neurology, Academic Specialist Center, Stockholm, Sweden

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Charlotte Höybye Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden

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and acid-base patterns. Hyponatremia in severely ill patients in the intensive care unit (ICU) is a known complication of somatic diseases such as pneumonia and heart failure ( 1 ). Several reports of hyponatremia at admission in COVID-19 patients

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0265
Volume/Issue:
Volume 10: Issue 7
Open access
Muhammad Fahad Arshad Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK
Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK

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Ahmed Iqbal Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK
Department of Oncology and Metabolism, The Medical School, The University of Sheffield, Sheffield, UK

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James Weeks Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK

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Ines Fonseca Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK

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Alia Munir Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK

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William Bennet Department of Diabetes and Endocrinology, Sheffield Teaching Hospitals, Sheffield, UK

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Severe Symptomatic Hyponatremia (SALSA) trial ( 20 , 21 ), investigators reported a similar rate of overcorrection in both groups (17.2% rapid intermittent bolus vs 24.2% slow continuous infusion). However, in this study, the overcorrection at 24 h was

Article Type:
Research Article
Collections:
Pituitary and Hypothalamus
DOI:
https://doi.org/10.1530/EC-22-0007
Volume/Issue:
Volume 11: Issue 5
Open access
Stephen Ball Department of Endocrinology, Central Manchester University Hospitals Foundation Trust, Manchester Royal Infirmary, Manchester, UK

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Julian Barth Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Blood Sciences, Leeds, UK

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Miles Levy Department of Endocrinology, University Hospitals of Leicester, Leicester Royal Infirmary, Leicester, UK

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the Society for Endocrinology Clinical Committee The Society for Endocrinology, 22 Apex Court, Woodlands, Bradley Stoke, Bristol, UK

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RH Thompson CJ. Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations . American Journal of Medicine 2013 126 S1 – S42 . ( doi:10.1016/
j.amjmed.2013.07.006 ) 2 Spasovski G Vanholder R Allolio B

Article Type:
Other
DOI:
https://doi.org/10.1530/EC-16-0058
Volume/Issue:
Volume 5: Issue 5
Open access