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M Ahmid, C G Perry, S F Ahmed and M G Shaikh

Introduction Growth hormone deficiency (GHD) is an endocrine condition that can potentially impact on an individual’s life from childhood, adolescence to young adulthood and beyond. In UK, the prevalence of congenital childhood-onset GHD (CO

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Kennett Sprogøe, Eva Mortensen, David B Karpf and Jonathan A Leff

in both an autocrine and paracrine fashion ( 4 ). GH and IGF-1 thus work in concert, with IGF-1 augmenting the anabolic actions of GH while opposing the hyperglycemic and lipolytic effects of GH ( 5 ). Growth hormone deficiency (GHD), which may be

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Charlotte Höybye, Laia Faseh, Christos Himonakos, Tomasz Pielak and Jesper Eugen-Olsen

.4 ± 1.1 mmol/L, high-density lipoprotein (HDL) cholesterol 1.3 ± 0.4 mmol/L and triglyceride 1.7 ± 1.1 mmol/L. Table 1 Baseline characteristics of 72 patients with growth hormone deficiency (GHD). Baseline characteristics ( N  = 72

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Johan Verhelst, Anders F Mattsson, Cecilia Camacho-Hübner, Anton Luger and Roger Abs

Introduction It is now well-recognized that patients with adult-onset growth hormone deficiency (AO-GHD), apart from experiencing a poor quality of life (QoL), present with an increased risk of developing a metabolic syndrome (MetS) ( 1 , 2

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Pinaki Dutta, Bhuvanesh Mahendran, K Shrinivas Reddy, Jasmina Ahluwalia, Kim Vaiphei, Rakesh K Kochhar, Prakamya Gupta, Anand Srinivasan, Mahesh Prakash, Kanchan Kumar Mukherjee, Viral N Shah, Girish Parthan and Anil Bhansali

growth hormone deficiency – benefits, side effects, and risks of growth hormone replacement . Frontiers in Endocrinology 2013 4 64 . ( doi:10.3389/fendo.2013.00064 ). 6 Pastuszak AW Lai WS Khera M Lipshultz LI . Systemic effects of growth

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Laura van Iersel, Sarah C Clement, Antoinette Y N Schouten-van Meeteren, Annemieke M Boot, Hedi L Claahsen-van der Grinten, Bernd Granzen, K Sen Han, Geert O Janssens, Erna M Michiels, A S Paul van Trotsenburg, W Peter Vandertop, Dannis G van Vuurden, Hubert N Caron, Leontien C M Kremer and Hanneke M van Santen

prevalence and latency times of cRT-induced HP dysfunction vary among patients, with growth hormone deficiency (GHD) usually occurring first and at a prevalence ranging from 29.0 to 39.1% ( 3 ). In contrast, central hypothyroidism primarily occurs after high

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Urszula Smyczyńska, Joanna Smyczyńska, Maciej Hilczer, Renata Stawerska, Ryszard Tadeusiewicz and Andrzej Lewiński

Committee and Ethics Committee of the Pediatric Endocrine Society . Guidelines for growth hormone and insulin-like growth factor-i treatment in children and adolescents: growth hormone deficiency, idiopathic short stature, and primary insulin-like growth

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Marilena Nakaguma, Fernanda A Correa, Lucas S Santana, Anna F F Benedetti, Ricardo V Perez, Martha K P Huayllas, Mirta B Miras, Mariana F A Funari, Antonio M Lerario, Berenice B Mendonca, Luciani R S Carvalho, Alexander A L Jorge and Ivo J P Arnhold

guardians gave their written informed consent. Figure 1 Clinical features of sequenced patients. CPHD, combined pituitary hormone deficiency; EPP, ectopic posterior pituitary lobe; IGHD, isolated growth hormone deficiency; NA, not available; NVPP, non

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Anastasia P Athanasoulia-Kaspar, Matthias K Auer, Günter K Stalla and Mira Jakovcevski

, high doses of glucocorticoid substitution therapy and older age at diagnosis are the most consistently identified risk factors associated with increased morbidity and mortality ( 18 , 19 ). In addition, growth hormone deficiency (GHD) has been linked

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Charlotte Höybye, Andreas F H Pfeiffer, Diego Ferone, Jens Sandahl Christiansen, David Gilfoyle, Eva Dam Christoffersen, Eva Mortensen, Jonathan A Leff and Michael Beckert

Introduction Hypothalamic–pituitary diseases and/or injury can lead to adult growth hormone deficiency (AGHD) ( 1 ). The decrease (or total loss) of growth hormone (GH) production, with a subsequent disruption in the hormone’s relationship