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Chao Xu Key Laboratory of Aquatic Nutrition and Feed Science of Jiangsu Province, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China

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Xiang-Fei Li Key Laboratory of Aquatic Nutrition and Feed Science of Jiangsu Province, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China

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Hong-Yan Tian Department of Ocean Technology, College of Marine and Biology Engineering, Yancheng Institute of Technology, Yancheng, Province Jiangsu, China

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Hua-Juan Shi Key Laboratory of Aquatic Nutrition and Feed Science of Jiangsu Province, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China

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Ding-Dong Zhang Key Laboratory of Aquatic Nutrition and Feed Science of Jiangsu Province, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China

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Kenneth Prudence Abasubong Key Laboratory of Aquatic Nutrition and Feed Science of Jiangsu Province, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China

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Wen-Bin Liu Key Laboratory of Aquatic Nutrition and Feed Science of Jiangsu Province, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, China

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(AMPK) has attracted considerable attention, due to its central role in governing glucose homeostasis. The activation of AMPK can lead to a series of physiological responses of the glycolipid metabolism by affecting intracellular signal transduction

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Xinyuan Zhang Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China
School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China

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Suiyan Li School of Life Science and Engineering, Southwest Jiaotong University, Chengdu, Sichuan, China

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Hongwei Liu Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China

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Huai Bai Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China

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Qingqing Liu Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China

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Chunyi Yang Department of Obstetrics and Gynecology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China

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Ping Fan Laboratory of Genetic Disease and Perinatal Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China

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glycolipid metabolism (e.g. metformin) within 3 months before the study; (ii) pregnancy or luteal menstrual phase, which can also affect glycolipid metabolism and oxidative stress ( 29 , 30 ); (iii) smoking; and/or (iv) fasting glucose (Glu) ≥ 7.0 mmol/L and

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Ningning Gong Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China
Department of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, China

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Cuixia Gao Department of Ultrasonic Diagnosis, Gansu Provincial Hospital, Lanzhou, China

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Xuedi Chen Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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Yu Wang Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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Limin Tian Department of Endocrinology, Gansu Provincial Hospital, Lanzhou, China

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). Chemerin, an 18-kDa protein secreted by adipose tissue, plays a key role in adipocyte differentiation and also helps to regulate APN expression and glycolipid metabolism ( 11 ). Several studies have demonstrated that chemerin is directly linked to human

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Yang Yu Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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Hairong Hao Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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Linghui Kong Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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Jie Zhang Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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Feng Bai Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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Fei Guo Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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Pan Wei Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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Rui Chen Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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Wen Hu Department of Endocrinology and Metabolism, Huai’an Hospital Affiliated to Xuzhou Medical University and Huai’an Second People’s Hospital, Huai’an, Jiangsu, China

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glucose changes. Therefore, it was inferred that these disorders of glycolipid metabolism were associated with elevated branched amino acids. The body weight of the rats in the HFTD group was significantly higher than that of the control group at the

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