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Yao Chen and Shu-ying Fang

steroid biosynthesis and action, gonadotropic secretion and action, folliculogenesis, weight and energy regulation and insulin action ( 13 ). In this review, we aimed to provide an overview of the main genetic polymorphisms that were found or

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Katica Bajuk Studen and Marija Pfeifer

and its different phenotypes result from complex interactions between multiple genetic predisposing variants and environmental and lifestyle factors ( 2 ). Possible associations between several genetic polymorphisms in PCOS in relation to its metabolic

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Anastasia K Armeni, Konstantinos Assimakopoulos, Dimitra Marioli, Vassiliki Koika, Euthychia Michaelidou, Niki Mourtzi, Gregoris Iconomou and Neoklis A Georgopoulos

oxytocin has been shown to increase expression of ERα ( 28 ). Therefore, the interaction of these two genetic polymorphisms could have an additive effect on female sexuality. The aim of the present study was to investigate the correlation of estrogen

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Anne Jouinot, Bernard Royer, Etienne Chatelut, Sotheara Moeung, Guillaume Assié, Audrey Thomas-Schoemann, Jérôme Bertherat, François Goldwasser and Benoit Blanchet

available. Finally, in our study, there was no linear relation between mitotane trough level and etoposide clearance, and the inter-individual variability was quite high (45.4%). Genetic polymorphisms in drug-metabolizing enzymes ( 25 ), and

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Piera Rizzolo, Valentina Silvestri, Virginia Valentini, Veronica Zelli, Agostino Bucalo, Ines Zanna, Simonetta Bianchi, Maria Grazia Tibiletti, Antonio Russo, Liliana Varesco, Gianluca Tedaldi, Bernardo Bonanni, Jacopo Azzollini, Siranoush Manoukian, Anna Coppa, Giuseppe Giannini, Laura Cortesi, Alessandra Viel, Marco Montagna, Paolo Peterlongo, Paolo Radice, Domenico Palli and Laura Ottini

.0 Discussion Estrogens play a relevant role in MBC; thus, genetic polymorphisms of genes involved in estrogen metabolism may have an impact on MBC susceptibility. The possible role of CYP17A1 rs743572 polymorphism in MBC risk has been analyzed by two

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Weiwei He, Bin Wang, Kaida Mu, Jing Zhang, Yanping Yang, Wei Yao, Sheli Li and Jin-an Zhang

pathogenesis of GD and found that polymorphisms of PTPN22 and CTLA4 are associated with the pathogenesis of GD, suggesting that genetic polymorphism plays a key role in the pathogenesis and progression of GD ( 12 , 13 ). Signal transducer and activator of

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Djeda Belharazem, Matthias Kirchner, Franziska Geissler, Peter Bugert, Martin Spahn, Burkhard Kneitz, Hubertus Riedmiller, Christian Sauer, Stefan Küffer, Lutz Trojan, Christian Bolenz, Maurice Stephan Michel, Alexander Marx and Philipp Ströbel

Nix W Schalke B Gold R Muller-Hermelink HK Peterson P Marx A . Common cellular and diverse genetic basis of thymoma-associated myasthenia gravis: role of MHC class II and AIRE genes and genetic polymorphisms . Annals of the New York

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Yael Sofer, Nava Nevo, Michal Vechoropoulos, Gabi Shefer, Etty Osher, Nathan Landis, Karen Tordjman, Geoffrey L Hammond and Naftali Stern

shown that specific genetic polymorphisms of SHBG were not only predictive of SHBG protein levels, but also of the apparently consequent risk of type 2 diabetes in men and women ( 12 , 30 ). Also, one study suggested an association between a

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Yessica Agudelo-Zapata, Luis Miguel Maldonado-Acosta, Héctor Fabio Sandoval-Alzate, Natalia Elvira Poveda, María Fernanda Garcés, Jonathan Alexander Cortés-Vásquez, Andrés Felipe Linares-Vaca, Carlos Alejandro Mancera-Rodríguez, Shahar Alexandra Perea-Ariza, Karen Yuliana Ramírez-Iriarte, Camilo Andrés Castro-Saldarriaga, Juan Manuel Arteaga-Diaz, Roberto Franco-Vega, Edith Ángel-Müller, Arturo José Parada-Baños and Jorge E Caminos

, probably due ultraviolet light, lifestyle habits and genetic polymorphisms in the vitamin D receptor gene ( VDR ) and the vitamin D-binding protein gene ( DBP ) as other authors have discussed before ( 29 ). Therefore, the significant increase in serum 25

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Anastasia P Athanasoulia-Kaspar, Kathrin H Popp and Gunter Karl Stalla

), located on chromosome 7 ( 22 ), that transports substrates – among them cabergoline – back into the blood circulation, thus protecting the central nervous system from harmful substances. Specific genetic polymorphisms seem to correlate with different