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Shatha Alharazy Department of Physiology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

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M Denise Robertson Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK

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Susan Lanham-New Department of Nutritional Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK

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Muhammad Imran Naseer Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

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Adeel G Chaudhary Centre of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia
Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
Centre for Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

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Eman Alissa Department of Clinical Biochemistry, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

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measuring free vitamin D might be more precise in evaluating vitamin D status in populations with more than one ethnic group ( 19 , 24 ). For instance, it has been found that despite the lower total 25(OH)D levels in Black Americans in comparison with White

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Magdalena Zgliczyńska Department of Obstetrics, Perinatology and Neonatology, Centre of Postgraduate Medical Education, Cegłowska, Warsaw, Poland

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Magdalena Ostrowska Department of Endocrinology, Centre of Postgraduate Medical Education, Cegłowska, Warsaw, Poland

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Kinga Żebrowska Department of Obstetrics, Perinatology and Neonatology, Centre of Postgraduate Medical Education, Cegłowska, Warsaw, Poland

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Iwona Szymusik Department of Obstetrics, Perinatology and Neonatology, Centre of Postgraduate Medical Education, Cegłowska, Warsaw, Poland

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Konrad Kowalski Masdiag Sp. z o.o., Stefana Żeromskiego, Warsaw, Poland

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Dorota Leszczyńska Department of Endocrinology, Centre of Postgraduate Medical Education, Cegłowska, Warsaw, Poland

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Katarzyna Kosińska-Kaczyńska Department of Obstetrics, Perinatology and Neonatology, Centre of Postgraduate Medical Education, Cegłowska, Warsaw, Poland

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). In addition, the concentration of VDBP increases, thereby influencing the levels of free vitamin D metabolites. Lately, free metabolites have been proposed as potentially more representative of vitamin D status during pregnancy than total 25(OH)D, but

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Suma Uday Department of Endocrinology and Diabetes, Birmingham Children’s Hospital, Birmingham, UK

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Ardita Kongjonaj MEAL Specialist at Save the Children International, Albania Country Office, Tirana, Albania

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Magda Aguiar Health Economics Unit, University of Birmingham, Birmingham, UK

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Ted Tulchinsky Braun School of Public Health and Community Medicine, and Ashkelon College, Ashkelon, Israel

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Wolfgang Högler Department of Endocrinology and Diabetes, Birmingham Children’s Hospital, Birmingham, UK
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK

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. 1B . Financial family support and child benefits Patients pay for their prescription in 62% of countries (18/29), whereas governments provide free vitamin D supplies in 28% (8/29). In Italy and the UK, only families on low income support

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Yessica Agudelo-Zapata Division of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Luis Miguel Maldonado-Acosta Division of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Héctor Fabio Sandoval-Alzate Department of Human Nutrition, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Natalia Elvira Poveda Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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María Fernanda Garcés Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Jonathan Alexander Cortés-Vásquez Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Andrés Felipe Linares-Vaca Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Carlos Alejandro Mancera-Rodríguez Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Shahar Alexandra Perea-Ariza Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Karen Yuliana Ramírez-Iriarte Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Camilo Andrés Castro-Saldarriaga Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Juan Manuel Arteaga-Diaz Division of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Roberto Franco-Vega Division of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Edith Ángel-Müller Department of Obstetrics and Gynecology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Arturo José Parada-Baños Department of Obstetrics and Gynecology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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Jorge E Caminos Department of Physiology, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia

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CR Scott RT. Free vitamin D does not vary through the follicular phase of the menstrual cycle . Endocrine 2016 53 322 – 326 . ( https://doi.org/10.1007/s12020-016-0946-1 ) 10.1007/s12020-016-0946-1 27052515 16 Refaat B Ahmad J Idris

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Johanna Öberg Tromso Endocrine Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway

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Rolf Jorde Tromso Endocrine Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway

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Yngve Figenschau Tromso Endocrine Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway
Diagnostic Clinic, University Hospital of North Norway, Tromso, Norway

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Per Medbøe Thorsby Hormone Laboratory, Department of Medical Biochemistry and Biochemical Endocrinology and Metabolism Research Group, Oslo University Hospital, Aker, Oslo, Norway

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Sandra Rinne Dahl Hormone Laboratory, Department of Medical Biochemistry and Biochemical Endocrinology and Metabolism Research Group, Oslo University Hospital, Aker, Oslo, Norway

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Anne Winther Division of Neurosciences, Orthopedics and Rehabilitation Services, University Hospital of North Norway, Tromso, Norway

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Guri Grimnes Tromso Endocrine Research Group, Department of Clinical Medicine, UiT The Arctic University of Norway, Tromso, Norway
Division of Internal Medicine, University Hospital of North Norway, Tromso, Norway

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Endocrinology and Metabolism 2015 100 4140 – 4145 . ( https://doi.org/10.1210/jc.2015-2548 ) 34 Chhantyal K He L Mo J Yin M He T Chen Y Yang Y Zhang L Rong L . Free vitamin D correlate better with bone mineral density and thoracolumbar

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Behnaz Abiri Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Majid Valizadeh Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Amirhossein Ramezani Ahmadi Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

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Shirin Amini Department of Nutrition, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran

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Mohammad Nikoohemmat Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Faeze Abbaspour Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Farhad Hosseinpanah Obesity Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran

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Normal: 25(OH)D >20 ng/mL and PTH <65 pg/mL. Obesity: BMI >95th percentile. Normal: 15th–85th percentiles. – Obese children had higher level of PTH. Bioavailable and free vitamin D were lower in the obese group. There was no difference in terms of

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Stefan Pilz Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Armin Zittermann Clinic for Thoracic and Cardiovascular Surgery, Herz- und Diabeteszentrum NRW, Ruhr University Bochum, Bad Oeynhausen, Germany

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Christian Trummer Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Verena Theiler-Schwetz Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Elisabeth Lerchbaum Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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Martin H Keppel University Institute for Medical and Chemical Laboratory Diagnostics, Paracelsus Medical University, Salzburg, Austria

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Martin R Grübler Department of Cardiology, Swiss Cardiovascular Center Bern, Bern University Hospital, University of Bern, Bern, Switzerland

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Winfried März Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria
Medical Clinic V (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Ruperto-Carola University of Heidelberg, Heidelberg, Germany
Synlab Medical Center of Human Genetics Mannheim, Mannheim, Germany

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Marlene Pandis Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Graz, Austria

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only a small fraction (less than 1%) circulating in its unbound (free) form ( 34 ). Although some tissues can take up DBP-bound vitamin D metabolites by the megalin–cubilin system, most cells seem to be dependent on free vitamin D metabolites that

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