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Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia
Centre for Innovation in Personalized Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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measuring free vitamin D might be more precise in evaluating vitamin D status in populations with more than one ethnic group ( 19 , 24 ). For instance, it has been found that despite the lower total 25(OH)D levels in Black Americans in comparison with White
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). In addition, the concentration of VDBP increases, thereby influencing the levels of free vitamin D metabolites. Lately, free metabolites have been proposed as potentially more representative of vitamin D status during pregnancy than total 25(OH)D, but
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Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
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. 1B . Financial family support and child benefits Patients pay for their prescription in 62% of countries (18/29), whereas governments provide free vitamin D supplies in 28% (8/29). In Italy and the UK, only families on low income support
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CR Scott RT. Free vitamin D does not vary through the follicular phase of the menstrual cycle . Endocrine 2016 53 322 – 326 . ( https://doi.org/10.1007/s12020-016-0946-1 ) 10.1007/s12020-016-0946-1 27052515 16 Refaat B Ahmad J Idris
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Diagnostic Clinic, University Hospital of North Norway, Tromso, Norway
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Division of Internal Medicine, University Hospital of North Norway, Tromso, Norway
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Endocrinology and Metabolism 2015 100 4140 – 4145 . ( https://doi.org/10.1210/jc.2015-2548 ) 34 Chhantyal K He L Mo J Yin M He T Chen Y Yang Y Zhang L Rong L . Free vitamin D correlate better with bone mineral density and thoracolumbar
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Normal: 25(OH)D >20 ng/mL and PTH <65 pg/mL. Obesity: BMI >95th percentile. Normal: 15th–85th percentiles. – Obese children had higher level of PTH. Bioavailable and free vitamin D were lower in the obese group. There was no difference in terms of
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Medical Clinic V (Nephrology, Hypertensiology, Rheumatology, Endocrinology, Diabetology), Medical Faculty Mannheim, Ruperto-Carola University of Heidelberg, Heidelberg, Germany
Synlab Medical Center of Human Genetics Mannheim, Mannheim, Germany
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only a small fraction (less than 1%) circulating in its unbound (free) form ( 34 ). Although some tissues can take up DBP-bound vitamin D metabolites by the megalin–cubilin system, most cells seem to be dependent on free vitamin D metabolites that