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Carmen Sydlik, Ilja Dubinski, Susanne Bechtold, and Heinrich Schmidt

, as triiodothyronine/free triiodothyronine (T3/fT3) levels may be low ( 1 , 2 ). In healthy individuals, fT3 levels can be stable over a wide range of corresponding TSH levels ( 3 ). The regulation of thyroid hormones is reflected in an adjusting fT3

Open access

Xiaomin Nie, Yiting Xu, Xiaojing Ma, Yun Shen, Yufei Wang, and Yuqian Bao

( 3 ). Free triiodothyronine (FT3) is the bioactive form of thyroxines. FT3 regulates basal metabolic rate, promotes fat decomposition and acts on the cardiovascular system through adrenergic signaling ( 4 ). Previous studies have found that a high

Open access

Ling Sun, Wenwu Zhu, Yuan Ji, Ailin Zou, Lipeng Mao, Boyu Chi, Jianguang Jiang, Xuejun Zhou, Qingjie Wang, and Fengxiang Zhang

.13(0.62, 2,12) 0.313 AKI, acute kidney injury; BNP, brain natriuretic peptide; DBP, diastolic blood pressure; FT3, free triiodothyronine; FT4, free thyroxine; LVEF, left ventricular ejection fraction; NSTEMI, non-ST segment elevation myocardial

Open access

Chenjia Tang, Yanting Dong, Lusi Lu, and Nan Zhang

Medical International Limited, Shenzhen, China). CRP was determined using immunoturbidimetry. Triiodothyronine (T3), free triiodothyronine (fT3), thyroxine (T4), fT4, TSH, thyroid peroxidase antibody (aTPO), thyroglobulin antibody (aTG), and thyrotropin

Open access

Chun-feng Lu, Wang-shu Liu, Xiao-qin Ge, Feng Xu, Jian-bin Su, Xue-qin Wang, and Yan Wang

images, and biochemical indicators (each criterion must be met: low thyroid-stimulating hormone – TSH, high free triiodothyronine – FT3, high free thyroxine – FT4, elevated TSH receptor antibody – TRAb) ( 14 ). The exclusion criteria were as follows: (1

Open access

Jiayang Lin, Peizhen Zhang, Yan Huang, Xueyun Wei, Dan Guo, Jianfang Liu, Deying Liu, Yajuan Deng, Bingyan Xu, Chensihan Huang, Xiaoyu Yang, Yan Lu, Lijing Jia, and Huijie Zhang

) were measured using standard enzymatic methods. Total bilirubin (TBIL) and direct bilirubin (DBIL) were measured by diazotization method. Serum insulin, free triiodothyronine (T3), total T3, free thyroxine (T4), total T4, and TSH thyroid peroxide

Open access

Nannan Bian, Xiaomeng Sun, Biao Zhou, Lin Zhang, Qiu Wang, Yu An, Xiaohui Li, Yinhui Li, Jia Liu, Hua Meng, and Guang Wang

has been observed in obese individuals, such as elevated serum thyroid-stimulating hormone (TSH) level and high transformation of thyroxine (T4) to triiodothyronine (T3) ( 8 , 9 , 10 ). Serum TSH and free triiodothyronine (FT3) levels decreased in

Open access

Till Ittermann, Rehman Mehmood Khattak, Marcello R P Markus, Jens-Peter Kühn, Marie-Luise Kromrey, Giovanni Targher, Antje Steveling, Matthias Nauck, and Henry Völzke

-stimulating hormone (mIU/L) 1.19 (0.87, 1.60) 0.35 (0.25, 0.44) 3.88 (3.59, 5.27) Free triiodothyronine (fT3) (pmol/L) 4.63 (4.29, 5.05) 4.76 (4.35, 5.12) 4.45 (4.10, 4.80) Free thyroxine (fT4) (pmol/L) 13.3 (12.3, 14.4) 14.3 (13.0, 15

Open access

Qing Zhu, Jianbin Su, Xueqin Wang, Mengjie Tang, Yingying Gao, and Dongmei Zhang

examination: increases in serum total thyroxine (T4), triiodothyronine (T3), free thyroxine (FT4), free triiodothyronine (FT3), reverse T3 (rT3); declines in thyroid-stimulating hormone (TSH); and thyroid-stimulating antibody (TSAb) and other related

Open access

Ling Hu, Ting Li, Xiao-Ling Yin, and Yi Zou

Objective:

The purpose of this study was to explore the prevalence of thyroid nodules (TN) and metabolic syndrome (MS) and to analyze the correlation between TN and the components of MS.

Methods:

A total of 1526 subjects were divided into two groups: a TN group and a non-thyroid nodules (NTN) group. The height, weight, blood pressure, fasting blood glucose level, fasting plasma insulin level, serum lipid profile, uric acid level, serum thyroid-stimulating hormone (TSH) level, free triiodothyronine (FT3) level, and free thyroxine (FT4) level of each patient were measured. Insulin resistance (IR) was estimated by homeostasis model assessment of insulin resistance (HOMA-IR). Fatty liver and TN were detected by color Doppler ultrasonography.

Results:

(i) The overall prevalence of TN was 39.5%; it was significantly higher in women than in men (P < 0.01) and progressively increased with age in both sexes. (ii) The overall prevalence of MS was 25.6%; it was significantly higher in men than in women (P < 0.01) and progressively increased with age in both sexes. (iii) FT3 was significantly lower in the TN group than in the NTN group (P < 0.01). (iv) BMI, triglycerides, and HOMA-IR were higher in the TN group than in the NTN group (P < 0.05). (v) The existence of TN was significantly associated with overweight/obesity (OR = 1.03, 95% CI = 1.024–1.089), and with insulin resistance (IR) (OR = 1.98, 95% CI = 1.645–2.368), after adjusting for age and sex.

Conclusions:

The prevalence of thyroid nodules and metabolic syndrome in the Nanchang area increases with age, and overweight/obesity and IR in patients are associated with thyroid nodules.