Xiaojie Wang
Xiaojie Wang
Center for Clinical Epidemiology and Methodology (CCEM), Guangdong Second Provincial General Hospital, Guangzhou, China
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Zhiyuan Chen
Zhiyuan Chen
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Ziyi Li
Ziyi Li
Center for Clinical Epidemiology and Methodology (CCEM), Guangdong Second Provincial General Hospital, Guangzhou, China
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Bo Chen
Bo Chen
Department of Endocrinology, Guangdong Second Provincial General Hospital, Guangzhou, China
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Yong Qi
Yong Qi
Department of Orthopedics, Guangdong Second Provincial General Hospital, Guangzhou, China
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Guowei Li
Guowei Li
Center for Clinical Epidemiology and Methodology (CCEM), Guangdong Second Provincial General Hospital, Guangzhou, China
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
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Jonathan D Adachi
Jonathan D Adachi
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada
Department of Medicine, McMaster University, Hamilton, Canada
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Department of Medicine, McMaster University, Hamilton, Canada
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Introduction As a major public health issue, fall is the second leading cause of accidental or unintentional injury-induced deaths worldwide with considerable social and economic burden ( 1 ), which could lead to various serious consequences
Ananda A Santana-Ribeiro
Ananda A Santana-Ribeiro
Laboratory of Motor Control and Body Balance, Center for Health Science Research, Federal University of Sergipe, Sergipe, Brazil
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Giulliani A Moreira-Brasileiro
Giulliani A Moreira-Brasileiro
Laboratory of Motor Control and Body Balance, Center for Health Science Research, Federal University of Sergipe, Sergipe, Brazil
Department of Physical Therapy and Post-Graduate Program in Health Science, Federal University of Sergipe, The GREAT Group (GRupo de Estudos em ATividade física), Sergipe, Brazil
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Department of Physical Therapy and Post-Graduate Program in Health Science, Federal University of Sergipe, The GREAT Group (GRupo de Estudos em ATividade física), Sergipe, Brazil
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Manuel H Aguiar-Oliveira
Manuel H Aguiar-Oliveira
Division of Endocrinology, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Roberto Salvatori
Roberto Salvatori
Division of Endocrinology, Diabetes and Metabolism, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
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Vitor O Carvalho
Vitor O Carvalho
Department of Physical Therapy and Post-Graduate Program in Health Science, Federal University of Sergipe, The GREAT Group (GRupo de Estudos em ATividade física), Sergipe, Brazil
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Claudia K Alvim-Pereira
Claudia K Alvim-Pereira
Laboratory of Motor Control and Body Balance, Center for Health Science Research, Federal University of Sergipe, Sergipe, Brazil
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Carlos R Araújo-Daniel
Carlos R Araújo-Daniel
Department of Statistic and Actuarial Sciences, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Júlia G Reis-Costa
Júlia G Reis-Costa
Laboratory of Motor Control and Body Balance, Center for Health Science Research, Federal University of Sergipe, Sergipe, Brazil
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Alana L Andrade-Guimarães
Alana L Andrade-Guimarães
Laboratory of Motor Control and Body Balance, Center for Health Science Research, Federal University of Sergipe, Sergipe, Brazil
Department of Physical Therapy and Post-Graduate Program in Health Science, Federal University of Sergipe, The GREAT Group (GRupo de Estudos em ATividade física), Sergipe, Brazil
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Department of Physical Therapy and Post-Graduate Program in Health Science, Federal University of Sergipe, The GREAT Group (GRupo de Estudos em ATividade física), Sergipe, Brazil
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Alécia A Oliveira-Santos
Alécia A Oliveira-Santos
Division of Endocrinology, Federal University of Sergipe, Aracaju, Sergipe, Brazil
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Edgar R Vieira
Edgar R Vieira
Department of Physical Therapy and Neuroscience, Wertheims’ College of Nursing and Health Science, Florida International University, Miami, Florida, USA
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Miburge B Gois-Junior
Miburge B Gois-Junior
Laboratory of Motor Control and Body Balance, Center for Health Science Research, Federal University of Sergipe, Sergipe, Brazil
Department of Physical Therapy and Post-Graduate Program in Health Science, Federal University of Sergipe, The GREAT Group (GRupo de Estudos em ATividade física), Sergipe, Brazil
Department of Physical Therapy and Neuroscience, Wertheims’ College of Nursing and Health Science, Florida International University, Miami, Florida, USA
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Department of Physical Therapy and Post-Graduate Program in Health Science, Federal University of Sergipe, The GREAT Group (GRupo de Estudos em ATividade física), Sergipe, Brazil
Department of Physical Therapy and Neuroscience, Wertheims’ College of Nursing and Health Science, Florida International University, Miami, Florida, USA
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are more useful in neurological diseases, in which sensitivity is less relevant. The aims of this study were to assess walking, postural balance and fall risk in congenital, untreated, lifetime IGHD subjects. Methods Subjects In a cross
Thozhukat Sathyapalan
Thozhukat Sathyapalan
Department of Academic Diabetes, Endocrinology and Metabolism, Hull York Medical School, University of Hull, Hull, UK
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Anne-Marie Coady
Anne-Marie Coady
Department of Obstetric Ultrasound, Hull and East Yorkshire Women’s and Children’s Hospital, Hull, UK
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Eric S Kilpatrick
Eric S Kilpatrick
Department of Clinical Biochemistry, Sidra Medical and Research Center, Doha, Qatar
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Stephen L Atkin
Stephen L Atkin
Department of Medicine, Weill Cornell Medical College, Doha, Qatar
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in IR would have resulted in fall in the β-cell requirements. Another possibility is that the statin could have a direct deleterious effect on β-cells by multiple mechanisms. Statins have been shown to inhibit this glucose-induced calcium signalling
Gavin P Vinson
Gavin P Vinson
School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK
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Caroline H Brennan
Caroline H Brennan
School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK
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in comparison with concentrations crossing the blood–brain barrier, and they are not thought to be produced in the brain to any great extent (113, 114) . Remarkably then, of the known neurosteroids, the corticosteroids may fall into a group of their
Jeremy Turner
Jeremy Turner
Norfolk and Norwich University Hospital, Colney Lane, Norwich, UK
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Neil Gittoes
Neil Gittoes
Centre for Endocrinology, Diabetes and Metabolism, University Hospitals Birmingham & University of Birmingham, Birmingham Health Partners, Birmingham, UK
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Peter Selby
Peter Selby
Department of Medicine, Manchester Royal Infirmary, Manchester, UK
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the Society for Endocrinology Clinical Committee
the Society for Endocrinology Clinical Committee
The Society for Endocrinology, 22 Apex Court, Woodlands, Bradley Stoke, Bristol, UK
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therapy as early as possible. This guideline aims to take the non-specialist through the initial phase of assessment and management. Clinical presentation Symptoms of hypocalcaemia typically develop when adjusted serum calcium levels fall below
Guillem Cuatrecasas
Guillem Cuatrecasas
Endocrinology Department, Hospital Quiron-Teknon, CPEN S.L., Barcelona, Spain
Universitat Oberta Catalunya (UOC), Barcelona, Spain
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Universitat Oberta Catalunya (UOC), Barcelona, Spain
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Hatice Kumru
Hatice Kumru
Institut Guttmann, Institut Universitari de Neurorehabilitació Adscrit a la UAB, Barcelona, Spain
Univ Autònoma de Barcelona, Cerdanyola del Vallès, Spain
Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Barcelona, Spain
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Univ Autònoma de Barcelona, Cerdanyola del Vallès, Spain
Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Barcelona, Spain
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M Josep Coves
M Josep Coves
Endocrinology Department, Hospital Quiron-Teknon, CPEN S.L., Barcelona, Spain
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Joan Vidal
Joan Vidal
Institut Guttmann, Institut Universitari de Neurorehabilitació Adscrit a la UAB, Barcelona, Spain
Univ Autònoma de Barcelona, Cerdanyola del Vallès, Spain
Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Barcelona, Spain
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Univ Autònoma de Barcelona, Cerdanyola del Vallès, Spain
Fundació Institut d’Investigació en Ciències de la Salut Germans Trias i Pujol, Barcelona, Spain
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F 12 A Th 4 Work accident 6.8 Yes Placebo 39 M 18 A Th 4 Traffic accident 1.9 Yes GH 27 M 24 A Th 4 Traffic accident 7.4 Yes Placebo 24 M 16 A Th 5 Falling from three 2
Barbara J Boucher
Barbara J Boucher
The Blizard Institute, Queen Mary University of London, London, UK
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up by a health professional. Overall uptake was poor and tended to fall over time as it was difficult to access and not well publicised. Uptake was much higher when these vouchers could be offered locally to all eligible women ( 19 , 20 ). Take up of
Bliss Anderson
Bliss Anderson
Department of Endocrinology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
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Daniel L Morganstein
Daniel L Morganstein
Department of Endocrinology, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
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regular testing of thyroid function during treatment. Attempting to predict the onset of hypophysitis with subtle changes to thyroid function tests has been examined. Two studies have described a fall in TSH in the cycle of treatment prior to the onset of
Franka S Schaebs
Franka S Schaebs
Interim Group Primatology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Saxony, Germany
ZLS, University of Leipzig, Leipzig, Saxony, Germany
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ZLS, University of Leipzig, Leipzig, Saxony, Germany
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Gwen Wirobski
Gwen Wirobski
Domestication Lab, Wolf Science Center, Konrad Lorenz Institute of Ethology, University of Veterinary Medicine Vienna, Vienna, Austria
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Sarah Marshall-Pescini
Sarah Marshall-Pescini
Domestication Lab, Wolf Science Center, Konrad Lorenz Institute of Ethology, University of Veterinary Medicine Vienna, Vienna, Austria
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Friederike Range
Friederike Range
Domestication Lab, Wolf Science Center, Konrad Lorenz Institute of Ethology, University of Veterinary Medicine Vienna, Vienna, Austria
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Tobias Deschner
Tobias Deschner
Interim Group Primatology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Saxony, Germany
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falling within the lower range of the assay may be associated with considerable variation calling for careful interpretation as subtle differences in magnitude (effect sizes) may not be detected reliably. Intra-assay coefficient of variance, calculated via
Line Tang Møllehave
Line Tang Møllehave
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark
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Marie Holm Eliasen
Marie Holm Eliasen
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark
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Ieva Strēle
Ieva Strēle
The Institute of Occupational Safety and Environmental Health, Riga Stradiņš University, Riga, Latvia
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Allan Linneberg
Allan Linneberg
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Rodrigo Moreno-Reyes
Rodrigo Moreno-Reyes
Nuclear Medicine Department, Erasme Hospital, Brussels, Belgium
Université Libre de Bruxelles, Bruxelles, Belgium
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Université Libre de Bruxelles, Bruxelles, Belgium
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Ludmila B Ivanova
Ludmila B Ivanova
Faculty of Medicine, Sofia University St. Kl. Ohridski, Sofia, Bulgaria
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Zvonko Kusić
Zvonko Kusić
Croatian Academy of Sciences and Arts, Zagreb, Croatia
School of Medicine, Zagreb, Croatia
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School of Medicine, Zagreb, Croatia
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Iris Erlund
Iris Erlund
Department of Government Services, Finnish Institute for Health and Welfare, Helsinki, Finland
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Till Ittermann
Till Ittermann
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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Endre V Nagy
Endre V Nagy
Division of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
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Ingibjorg Gunnarsdottir
Ingibjorg Gunnarsdottir
Faculty of Food Science and Nutrition, University of Iceland, Reykjavik, Iceland
Department of Clinical Nutrition, Landspitali-National University Hospital, Reykjavik, Iceland
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Department of Clinical Nutrition, Landspitali-National University Hospital, Reykjavik, Iceland
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Jonathan Eli Arbelle
Jonathan Eli Arbelle
Division of Medicine, Maccabi Healthcare Services, Tel Aviv, Israel
Goldman School of Medicine, Ben Gurion University of the Negev, Beer Sheva, Israel
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Goldman School of Medicine, Ben Gurion University of the Negev, Beer Sheva, Israel
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Aaron Milton Troen
Aaron Milton Troen
The Institute of Biochemistry Food Science and Nutrition, The Hebrew University of Jerusalem, Rehovot, Israel
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Valdis Pīrāgs
Valdis Pīrāgs
Internal Medicine, University of Latvia, Riga, Latvia
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Lisbeth Dahl
Lisbeth Dahl
Seafood, Nutrition and Environmental State, Institute of Marine Research (IMR), Bergen, Norway
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Alicja Hubalewska-Dydejczyk
Alicja Hubalewska-Dydejczyk
Chair and Department of Endocrinology, Jagiellonian University, Medical College, Cracow, Poland
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Malgorzata Trofimiuk-Müldner
Malgorzata Trofimiuk-Müldner
Chair and Department of Endocrinology, Jagiellonian University, Medical College, Cracow, Poland
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João Jacome de Castro
João Jacome de Castro
Endocrine Department, Armed Forces Hospital, Lisbon, Portugal
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Mafalda Marcelino
Mafalda Marcelino
Endocrine Department, Armed Forces Hospital, Lisbon, Portugal
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Simona Gaberšček
Simona Gaberšček
Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Katja Zaltel
Katja Zaltel
Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia
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Manuel Puig-Domingo
Manuel Puig-Domingo
Department of Endocrinology and Nutrition, Germans Trias Research Institute and Hospital, Badalona, Spain
Universitat Autònoma de Barcelona, Barcelona, Spain
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Universitat Autònoma de Barcelona, Barcelona, Spain
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Lluis Vila
Lluis Vila
Endocrinology and Nutrition Service, Hospital Moisés Broggi, Sant Juan Despi, Barcelona, Spain
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Sofia Manousou
Sofia Manousou
Sahlgrenska Academy, Institute of Medicine, Gothenburg, Sweden
Frölunda Specialist Hospital, Västra Frölunda, Sweden
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Frölunda Specialist Hospital, Västra Frölunda, Sweden
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Helena Filipsson Nyström
Helena Filipsson Nyström
Department of Endocrinology, Specialist Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Wallenberg Centre of Molecular and Translational Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
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Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
Wallenberg Centre of Molecular and Translational Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
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Michael Bruce Zimmermann
Michael Bruce Zimmermann
Health Sciences and Technology, ETH Zurich, Zurich, Switzerland
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Karen R Mullan
Karen R Mullan
Regional Centre for Endocrinology and Diabetes, Belfast Health and Social Care Trust, Belfast, UK
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Jayne Valerie Woodside
Jayne Valerie Woodside
Centre for Public Health, Queen’s University Belfast, Belfast, UK
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Henry Völzke
Henry Völzke
Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany
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Betina Heinsbæk Thuesen
Betina Heinsbæk Thuesen
Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg, Denmark
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). Furthermore, during 2001–2009/2015 a fall in threshold for treatment initiation of thyroid hormone therapy was observed in both Great Britain and in Denmark leading to more prescriptions of thyroid hormone therapy, but the fall in treatment threshold was
