progression rate and improves life expectancy, Pompe disease continues to be a progressive metabolic myopathy ( 3 , 4 ). Therefore, new treatments are continuously being investigated in Pompe disease. Exercise is one intervention, which has the potential to
Nicolai Preisler, Pascal Laforêt, Karen Lindhardt Madsen, Edith Husu, Christoffer Rasmus Vissing, Gitte Hedermann, Henrik Galbo, Christopher Lindberg and John Vissing
Li Jing and Wang Chengji
factors including dyslipidemia, hypertension and cardiovascular disease ( 2 ), thus putting a severe burden on our global health care systems. Exercise plays a crucial role in the prevention and treatment of several chronic diseases, including glucose
Jia Li, Yan Zhao, Caoxin Huang, Zheng Chen, Xiulin Shi, Long Li, Zhong Chen and Xuejun Li
exercise. Several clinical trials have verified the benefit of exercise for NAFLD patients, including decreases in the intrahepatic triglyceride (IHTG) content, weight, waist circumference, body fat and blood pressure ( 1 , 2 , 3 , 4 ). Moreover
Lawrence D Hayes, Peter Herbert, Nicholas F Sculthorpe and Fergal M Grace
fitness can be achieved with exercise training in older adults ( 10 , 11 ), the potential of aging men to increase systemic testosterone through exercise is poorly understood. Whilst some authors have reported elevated total testosterone (TT) in highly
Wenqi Yang, Ling Liu, Yuan Wei, Chunlu Fang, Fu Zhou, Jinbao Chen, Qinghua Han, Meifang Huang, Xuan Tan, Qiuyue Liu, Qiang Pan, Lu Zhang, Xiaojuan Lei and Liangming Li
the liver and adipose tissue ( 11 , 12 , 13 ). The beneficial effects of exercise on glucose homeostasis are well documented ( 14 ), and exercise has been shown to reduce adipogenesis, alleviate adipose tissue inflammation and improve the disturbed
Charlotte Janus, Dorte Vistisen, Hanan Amadid, Daniel R Witte, Torsten Lauritzen, Søren Brage, Anne-Louise Bjerregaard, Torben Hansen, Jens J Holst, Marit E Jørgensen, Oluf Pedersen, Kristine Færch and Signe S Torekov
and digestive functions such as motility, absorption, and secretion. During exhausting endurance exercise (e.g. long-distance running), this can lead to unpleasant symptoms such as diarrhea and intestinal cramps ( 10 ). At low-to-moderate intensity
Liza Haqq, James McFarlane, Gudrun Dieberg and Neil Smart
benefits of exercise training and dietary interventions on a range of endocrinal outcomes in women with PCOS. Subjects and methods Search strategy Potential studies were identified by conducting a systematic search using PubMed ( www
Alexander Tacey, Lewan Parker, Bu B Yeap, John Joseph, Ee M Lim, Andrew Garnham, David L Hare, Tara Brennan-Speranza and Itamar Levinger
treatment likely has an ergogenic effect on exercise capacity and performance ( 7 , 8 ). However, the effects of acute (single dose) GC administration are less clear, largely due to limited research. As such, it is important to determine the biological
J Chycki, A Zajac, M Michalczyk, A Maszczyk and J Langfort
homeostasis. Physical exercise is recognized as a strong environmental stimulus of lipolysis in WAT, being a significant preventive factor against the so-called non-communicable diseases ( 2 , 5 ). Most exercise protocols designed to induce AT loss have
N K Stepto, D Hiam, M Gibson-Helm, S Cassar, C L Harrison, S K Hutchison, A E Joham, B J Canny, A Moreno-Asso, B J Strauss, N Hatzirodos, R J Rodgers and H J Teede
insulin resistance in PCOS remain ill defined ( 8 , 13 ). Therapeutic strategies in PCOS include medical therapy (metformin) and weight management via diet and exercise ( 6 , 14 , 15 ), which reduce but not reverse insulin resistance and fail to
