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physician considered the event unlikely to be related to GH treatment. In conclusion, the evidence suggests a favourable safety profile of GH treatment in patients with NS, including those with cardiovascular comorbidities and those receiving concomitant
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anticoagulation in TAF until an euthyroid state and sinus rhythm are achieved ( 10 , 11 ). Evidence is conflicting on the efficacy and safety of anticoagulation in people with TAF and most randomized controlled trials (RCTs) on anticoagulation in AF have excluded
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-mediated organ damage, such as LVH and microalbuminuria ( 7 , 8 , 9 ). IR is implicated in the onset and progression of metabolic cardiomyopathy, as evidenced by experimental studies demonstrating its negative impact on cellular metabolism and signaling, which
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occurred within 3 months of surgery were categorized as being provoked by a major transient factor. Interestingly, recent evidence shows that VTE often occurs before surgery or is unrelated to surgery ( 9 , 11 , 16 , 17 ), with a prevalence of VTEs not
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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the neuropsychiatric effects of dexamethasone ( 16 ). There is upcoming evidence that certain subgroups of childhood leukemia patients suffering from side effects from dexamethasone may benefit from cortisol add-on to refill and re-activate brain MR
Sahlgrenska Osteoporosis Centre, Center for Bone and Arthritis Research (CBAR), Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden
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panel of sex steroid hormones in human CSF. The measured CSF sex steroid levels were in the lower pg/mL range, and for immunoassays, evidence exists of analytical interferences at these low levels ( 17 , 18 ). Future research on CSF sex steroid levels
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Cardiovascular Research Center, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan
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trials have collectively failed to generate convincing evidence for the therapeutic efficacy of vitamin D on hyperlipidemia ( 13 , 14 , 18 , 19 ). Thus, we aimed to investigate the associations between increased serum vitamin D concentrations and lipid
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loss of IDOL function leads to a corresponding increase and reduction in plasma LDL levels, respectively ( 4 ). In addition to experimental data, genetic studies have provided further evidence to support the notion that IDOL may potentially be involved
Department of Clinical Biochemistry, Hospital of South West Jutland, Esbjerg, Denmark
Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Department of Internal Medicine, Lillebaelt Hospital, Kolding, Denmark
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Department of Clinical Biochemistry, Hospital of South West Jutland, Esbjerg, Denmark
Department of Haematology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands
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Werner RJ Boehncke WH Jost SS Scharrer I Leg ulcers in Klinefelter’s syndrome – further evidence for an involvement of plasminogen activator inhibitor-1 . British Journal of Dermatology 1997 136 341 – 344 . 11 Seth A Rajpal S Penn RL
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Renal Division, Children’s Hospital Affiliated to Capital Institute of Pediatrics, Beijing, China
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of Medical Sciences , 2015 . 19 De Jong JC Van Der Vliet WA Van Den Heuvel LP Willems PH Knoers NV Bindels RJ . Functional expression of mutations in the human NaCl cotransporter: evidence for impaired routing mechanisms in Gitelman