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C L Bodinham, L Smith, E L Thomas, J D Bell, J R Swann, A Costabile, D Russell-Jones, A M Umpleby and M D Robertson

period, participants completed a 7-day food and drink diary and a 7-day bowel habit and symptom diary. Participants attended for three study visits at the end of each intervention: i) a two-step euglycemic–hyperinsulinemic clamp combined with an infusion

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Kaisa K Ivaska, Maikki K Heliövaara, Pertti Ebeling, Marco Bucci, Ville Huovinen, H Kalervo Väänänen, Pirjo Nuutila and Heikki A Koistinen

employed the euglycemic hyperinsulinemic clamp technique (29) to study whether insulin affects markers of bone remodeling, particularly OC, in humans. A few studies have applied this technique to assess acute insulin-driven changes in bone metabolism (30

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Taísa A R Vicente, Ívina E S Rocha, Roberto Salvatori, Carla R P Oliveira, Rossana M C Pereira, Anita H O Souza, Viviane C Campos, Elenilde G Santos, Rachel D C Araújo Diniz, Eugênia H O Valença, Carlos C Epitácio-Pereira, Mario C P Oliveira, Andrea Mari and Manuel H Aguiar-Oliveira

measurement has an excellent correlation with the euglycemic–hyperinsulinemic clamp (24) , the ‘gold standard’ method to assess IS, used in acquired AOGHD (25) . The increase of IS in the IGHD group may be caused by the marked reduction in GH levels and

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Antonia Ertelt, Ann-Kristin Barton, Robert R Schmitz and Heidrun Gehlen

proliferation and tissue growth and repair, might be another key in the pathogenesis of laminitis (126) . Gene expression for IGF1 receptor (IGF1R) and insulin receptor were decreased by 13- to 32-fold during a prolonged euglycemic, hyperinsulinemic clamp test

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Alessandra Gambineri and Carla Pelusi

-to-male transsexuals demonstrated that testosterone-ester administration at the dose of 250 mg i.m. every 2 weeks produced a significant increase in visceral adipose tissue and a decrease in insulin sensitivity evaluated by the euglycemic–hyperinsulinemic clamp ( 19

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Lars Peter Sørensen, Tina Parkner, Esben Søndergaard, Bo Martin Bibby, Holger Jon Møller and Søren Nielsen

euglycemic hyperinsulinemic clamp technique (26) , which was evident in normal-weight and obese healthy individuals (20, 21, 26) , as well as in individuals with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and T2DM (24

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Signe Frøssing, Malin Nylander, Caroline Kistorp, Sven O Skouby and Jens Faber

between MR-proADM levels and BMI or VAT, both at baseline and after weight reduction. With respect to insulin resistance, previous studies are conflicting. During a euglycemic hyperinsulinemic clamp in obese individuals, plasma ADM increased in response

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Jakob Høgild Langdahl, Anja Lisbeth Frederiksen, John Vissing, Morten Frost, Knud Bonnet Yderstræde and Per Heden Andersen

been shown to be inversely correlated with glucose uptake in the left ventricle of the heart during an euglycemic hyperinsulinemic clamp in m.3243A>G carriers ( 39 ). Furthermore, glycolysis and insulin signaling are suppressed in red fibers of

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Dorte Glintborg, Magda Lambaa Altinok, Pernille Ravn, Kurt Bjerregaard Stage, Kurt Højlund and Marianne Andersen

urinary cortisol excretion. We used a combination of disease-specific and generic questionnaires to describe HRQoL. Measures of insulin sensitivity were calculated at fasting and by measures derived from 3-h OGTT. The euglycemic–hyperinsulinemic clamp is

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Alessandro Ciresi, Stefano Radellini, Valentina Guarnotta, Maria Grazia Mineo and Carla Giordano

-016-0475-z 27126309 40 Ciresi A Guarnotta V Pizzolanti G Giordano C . Comparison between euglycemic hyperinsulinemic clamp and surrogate indices of insulin sensitivity in children with growth hormone deficiency . Growth Hormone and IGF Research