Department of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, China
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subjects ( 22 ). We speculated that these differences may be associated with TSH levels. Our present study aimed to explore changes of endothelial function in rats with sHT exhibiting different levels of TSH. The relationship between APN, chemerin and TNF
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Vascular Laboratory, Cairo University, Cairo, Egypt
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same skilled sonographer. Endothelial function has been assessed by measuring the percent of change in blood flow following heat-mediated vasodilation using laser Doppler flowmetry (Pen Flux System 5000, Perimed AB) in patients and controls. Skin
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major factor in the development of atherosclerosis ( 5 ). Measurement of flow-mediated vasodilation (FMD) of the brachial artery has been widely used to assess the endothelial function in humans as a reflection of endothelial nitric oxide (NO
Department of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, China
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Department of Endocrinology and Diabetes, Pakistan Kidney and Liver Institute and Research Centre, Knowledge City, Lahore, Pakistan
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Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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developing subclinical atherosclerosis even at a young age ( 3 , 4 ). Endothelial dysfunction is an early indicator of the atherosclerotic process, and several studies have demonstrated abnormal endothelial function assessed by flow-mediated dilation and
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal
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Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal
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subclinical) exhibit impaired endothelial function that improves with TH replacement therapy ( 61 , 63 ). In the Rotterdam Study mentioned above, patients with SCH had higher prevalence of aortic calcification and myocardial infarction, especially those who
Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark
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Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark
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Department of Internal Medicine, Endocrine Unit, Herlev Gentofte Hospital, Herlev, Denmark
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Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
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liraglutide (1.8 mg/day for six months) in 36 obese women with and without PCOS found improved endothelial function, seen as reduced levels of cell adhesion markers as well as slightly reduced clot lysis area, a complex measure of clot formation, density and
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). This was observed even at very early ages, and with a trend of deterioration of endothelial function from lean to overweight and obese PCOS women, with excess visceral fat accumulation being a very important predictor of atherosclerosis in PCOS ( 32
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trained older males compared to controls ( 12 ), this is not always the case ( 13 ). For example, experimental data from our laboratory suggest masters athletes exhibit improved peak oxygen uptake, body composition and endothelial function compared with
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Faculty of Medicine, University of Latvia, Riga, Latvia
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improve endothelial function, promote glucose uptake, increase insulin production, decrease glucagon secretion, lower glucose production, and reduce inflammation. Similarly, both glucagon and insulin promote energy storage, stimulate insulin production