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Zeming Liu, Di Hu, Yihui Huang, Sichao Chen, Wen Zeng, Ling Zhou, Wei Zhou, Min Wang, Haifeng Feng, Wei Wei, Chao Zhang, Danyang Chen and Liang Guo

incidence and mortality rate of pediatric thyroid cancer is low; moreover, pediatric differentiated thyroid cancer has a higher rate of distant metastasis ( 4 ). Thus, there seems to be a significant need for relevant studies in children and adolescents with

Open access

Dario de Biase, Federica Torricelli, Moira Ragazzi, Benedetta Donati, Elisabetta Kuhn, Michela Visani, Giorgia Acquaviva, Annalisa Pession, Giovanni Tallini, Simonetta Piana and Alessia Ciarrocchi

-differentiated PTC ( N  = 85)that did not develop distant metastasis with a minimum follow-up of 8 years. Part of this patient cohort has been the object of our previous study ( 14 ). All analyses were performed from formalin-fixed and paraffin-embedded (FFPE

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Huy Gia Vuong, Nguyen Phuoc Long, Nguyen Hoang Anh, Tran Diem Nghi, Mai Van Hieu, Le Phi Hung, Tadao Nakazawa, Ryohei Katoh and Tetsuo Kondo

, year of publication, time of operation, criteria for TCVPTC/PTC-TCF, multifocality, extrathyroidal extension, lymph node metastasis, pathological T factor of the TNM staging system (pT factor), distant metastasis at time of presentation, tumor

Open access

Andrea Mazurat, Andrea Torroni, Jane Hendrickson-Rebizant, Harbinder Benning, Richard W Nason and K Alok Pathak

(22.3%) patients had regional lymph node involvement and 54 (2.6%) had distant metastasis. On January 1, 2013, 1658 (78.5%) patients had no evidence of disease; 49 (2.3%) patients were alive with disease; 105 (5.0%) patients were dead because of

Open access

Huy Gia Vuong, Uyen N P Duong, Ahmed M A Altibi, Hanh T T Ngo, Thong Quang Pham, Hung Minh Tran, Greta Gandolfi and Lewis Hassell

). However, there is a small proportion of cases with aggressive features at presentation that develop early distant metastasis or relapse and are associated with adverse outcomes. Various clinicopathological factors have been investigated as prognostic

Open access

Logan Mills, Panagiotis Drymousis, Yogesh Vashist, Christoph Burdelski, Andreas Prachalias, Parthi Srinivasan, Krishna Menon, Corina Cotoi, Saboor Khan, Judith Cave, Thomas Armstrong, Martin O Weickert, Jakob Izbicki, Joerg Schrader, Andreja Frilling, John K Ramage and Raj Srirajaskanthan

node metastasis or distant metastasis (synchronous or metachronous). Tumours were staged according to the ENETS TNM system for pancreatic neuroendocrine tumours ( 20 ). Where staining with the Ki67 antigen was available, grading was assigned using the

Open access

Chao-bin He, Yu Zhang, Zhi-yuan Cai and Xiao-jun Lin

adenocarcinoma, the primary source of mortality of metastatic PNETs is mainly the dysfunction of metastatic organs, such as liver failure ( 6 ). Although the presence of distant metastasis is correlated with shortened long-term survival, the appropriately

Open access

Samira M Sadowski, Emanuel Christ, Benoit Bédat, Attila Kollár, Wolfram Karenovics, Aurel Perren, Frédéric Triponez and on behalf of the SwissNET registry

following R0 resection, with no evidence of local recurrence or distant metastasis on imaging. Survival analyses using the Kaplan–Meier method were performed to determine outcomes, and log-rank test was performed for comparison. Statistical analyses were

Open access

Yang Lv, Xu Han, Chunyan Zhang, Yuan Fang, Ning Pu, Yuan Ji, Dansong Wang, Xu Xuefeng and Wenhui Lou

rates owing to the hypersecretion of hormones or non­functioning based on the symptoms of space-occupying effects or the distant metastasis ( 1 ). Because of lack of specific manifestations, nonfunctioning pNETs (NF-pNETs) were more difficult to diagnose

Open access

Norra Kwong, Ellen Marqusee, Michael S Gordon, P Reed Larsen, Jeffrey R Garber, Matthew I Kim and Erik K Alexander

2013 37 1599 – 1605 . ( doi:10.1007/s00268-013-2006-9 ). 23 Lee J Soh EY . Differentiated thyroid carcinoma presenting with distant metastasis at initial diagnosis clinical outcomes and prognostic factors . Annals of Surgery 2010 251 114