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Gavin P Vinson School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK

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Caroline H Brennan School of Biological and Chemical Sciences, Queen Mary University of London, London E1 4NS, UK

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(the therapeutic corticosteroid of choice at the time) was soon applied in the management of meperidine and morphine withdrawal symptoms in men (5) , apparently with beneficial effects, while Lovell associated alcoholism and drug addiction with

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-13-0028
Volume/Issue:
Volume 2: Issue 3
Open access
Katica Bajuk Studen Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

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Simona Gaberšček Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

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Edvard Pirnat Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia

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Nataša Bedernjak Bajuk Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia

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Andreja Vendramin Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia

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Vito Majcen Department of Nuclear Medicine, SB Celje, Celje, Slovenia

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Katja Zaletel Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia
Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia

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-adrenergic-blocking drugs are added. In patients who fail to respond to NSAID or present initially with moderate-to-severe pain and/or thyrotoxic symptoms, corticosteroid (CS) treatment is recommended ( 1 ). The optimal CS treatment regimen for ST has not yet been

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-23-0054
Volume/Issue:
Volume 12: Issue 11
Open access
Lesley A Hill Departments of Cellular and Physiological Sciences and Obstetrics and Gynaecology, The University of British Columbia, Vancouver, British Columbia, Canada

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Zeynep Sumer-Bayraktar School of Life and Environmental Science, Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia

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John G Lewis Canterbury Health Laboratories, Christchurch, New Zealand

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Eva Morava Mayo Clinic, Department of Clinical Genomics, CIM, Rochester, Minnesota, USA

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Morten Thaysen-Andersen Department of Molecular Sciences, Macquarie University, Sydney, New South Wales, Australia

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Geoffrey L Hammond Departments of Cellular and Physiological Sciences and Obstetrics and Gynaecology, The University of British Columbia, Vancouver, British Columbia, Canada

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Introduction Corticosteroid-binding globulin (CBG) transports steroids in the blood and regulates their access to tissues and cells ( 1 , 2 ). Crystal structure analyses show that CBG contains a single hydrophobic steroid-binding site ( 3

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0242
Volume/Issue:
Volume 8: Issue 8
Open access
Muriel Houang Laboratoire des Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France

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Thao Nguyen-Khoa Centre Régional de Dépistage Néonatal-Ile de France, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France

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Thibaut Eguether Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France

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Bettina Ribault Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France

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Séverine Brabant Laboratoire d’Explorations Fonctionnelles, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France

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Michel Polak Centre Régional de Dépistage Néonatal-Ile de France, Hôpital Necker-Enfants Malades, AP-HP Centre Université de Paris, Paris, France
Université de Paris, INSERM, Institut IMAGINE, Hôpital Necker-Enfants Malades, AP-HP, Paris, France

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Irène Netchine Laboratoire des Explorations Fonctionnelles Endocriniennes, Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France
Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Hôpital Armand Trousseau, AP-HP Sorbonne Université, Paris, France

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Antonin Lamazière Sorbonne Université, INSERM, Centre de Recherche Saint-Antoine, Paris, France
Département de Métabolomique Clinique, Hôpital Saint-Antoine, AP-HP Sorbonne Université, Paris, France

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discriminant test, we questioned the mother regarding her medication. The mother happened to be on nasal spray corticosteroids (triamcinolone) throughout the pregnancy and during the neonatal period while she was breastfeeding. This significantly lowered all

Article Type:
Research Article
Collections:
Paediatric Endocrinology
DOI:
https://doi.org/10.1530/EC-22-0101
Volume/Issue:
Volume 11: Issue 6
Open access
Britt J van Keulen Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

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Michelle Romijn Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

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Bibian van der Voorn Department of Pediatric Endocrinology, Sophia Kinderziekenhuis, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

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Marita de Waard Emma Children’s Hospital, Amsterdam University Medical Centers, locations AMC and VUmc, Amsterdam, The Netherlands

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Michaela F Hartmann Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University, Giessen, Germany

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Johannes B van Goudoever Emma Children’s Hospital, Amsterdam University Medical Centers, locations AMC and VUmc, Amsterdam, The Netherlands

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Stefan A Wudy Steroid Research and Mass Spectrometry Unit, Laboratory for Translational Hormone Analytics, Pediatric Endocrinology & Diabetology, Center of Child and Adolescent Medicine, Justus-Liebig-University, Giessen, Germany

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Joost Rotteveel Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands

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Martijn J J Finken Department of Pediatric Endocrinology, Emma Children’s Hospital, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands
Department of Pediatrics, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Reproduction & Development Research Institute, de Boelelaan, Amsterdam, The Netherlands

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/kg/day). Outcomes were: (1) cortisol excretion rate (µg/kg/day), (2) the sum of all glucocorticoid metabolites or corticosteroid excretion rate (µg/kg/day), and (3) the ratio of 11-hydroxy (11-OH)/11-oxoandrostenedione (11-OXO) metabolites, as an estimate of 11B

Article Type:
Research Article
Collections:
Paediatric Endocrinology Collection
DOI:
https://doi.org/10.1530/EC-20-0587
Volume/Issue:
Volume 10: Issue 2
Open access
Ruth Percik Institute of Endocrinology, Diabetes and Metabolism, Sheba Medical Centre, Ramat Gan, Israel

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Sherwin Criseno Department of Endocrinology, University Hospital Birmingham, Birmingham, UK

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Safwaan Adam Department of Endocrinology, The Christie NHS Foundation Trust, Manchester, UK

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Kate Young Royal Marsden Hospital, London, UK

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Daniel L Morganstein Department of Endocrinology, Chelsea and Westminster Hospital, London, UK
Royal Marsden Hospital, London, UK

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glucocorticoids such as creams, inhalers or nasal sprays, including those used for non-ICPI-related toxicity (e.g. asthma). Where potentially suppressive doses of corticosteroids have been used ( 27 ), a careful weaning protocol should be followed (such as that in

Article Type:
Review Article
Collections:
Hormones and Cancer
DOI:
https://doi.org/10.1530/EC-22-0513
Volume/Issue:
Volume 12: Issue 5
Open access
Clara Lundetoft Clausen Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark

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Trine Holm Johannsen Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Niels Erik Skakkebæk Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Hanne Frederiksen Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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Thomas Benfield Center of Research & Disruption of Infectious Diseases, Department of Infectious Diseases, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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has surfaced, wherein certain studies have documented inadequately low cortisol levels ( 4 , 5 , 6 ). The latter has partly been attributed to critical illness-related corticosteroid insufficiency (CIRCI), a recurring phenomenon in patients with

Article Type:
Research Article
Collections:
Adrenal
DOI:
https://doi.org/10.1530/EC-24-0093
Volume/Issue:
Volume 13: Issue 8
Open access
Jana Ernst Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Grosse Steinstrasse, Halle (Saale), Germany

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Katharina Gert Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Grosse Steinstrasse, Halle (Saale), Germany

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Frank Bernhard Kraus Central Laboratory, University Hospital Halle (Saale), Ernst-Grube-Strasse, Halle (Saale), Germany

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Ulrike Elisabeth Rolle-Kampczyk Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research Leipzig, Leipzig, Germany

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Martin Wabitsch Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany

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Faramarz Dehghani Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Grosse Steinstrasse, Halle (Saale), Germany

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Kristina Schaedlich Department of Anatomy and Cell Biology, Faculty of Medicine, Martin Luther University Halle-Wittenberg, Grosse Steinstrasse, Halle (Saale), Germany

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conditions, androgens (androstenedione, androsterone, testosterone, dihydrotestosterone, etiocholanolone) and corticosteroids (corticosterone, aldosterone, 11-deoxycortisol, cortisol, cortisone) increased during adipogenesis. Furthermore, an androstenedione

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0549
Volume/Issue:
Volume 9: Issue 7
Open access
Pablo Abellán-Galiana Department of Endocrinology, Hospital General Universitari de Castelló, Castellón, Spain
Department of Medicine, Universidad Cardenal Herrera-CEU, CEU Universities, Castellón, Spain

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Carmen Fajardo-Montañana Department of Endocrinology, Hospital Universitario de la Ribera, Alzira, Spain

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Pedro Riesgo-Suárez Department of Neurosurgery, Hospital Universitario de la Ribera, Alzira, Spain

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Marcelino Pérez-Bermejo Department of Nursing, Universidad Católica de Valencia, Valencia, Spain

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Celia Ríos-Pérez Centro de Salud Tavernes de la Valldigna, Hospital Comarcal Francesc de Borja, Gandía, Spain

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José Gómez-Vela Department of Endocrinology, Hospital Universitario de la Ribera, Alzira, Spain

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specific treatment for hypercortisolism (ketoconazole and/or cabergoline) was suspended before surgery (at least 1 week), avoiding the use of corticosteroids in the surgical phase. Imaging studies using neuronavigation protocols were made, together with a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-19-0297
Volume/Issue:
Volume 8: Issue 9
Open access
Athanasios D Anastasilakis Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece

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Marina Tsoli 1st Propaedeutic Department of Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Gregory Kaltsas 1st Propaedeutic Department of Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece

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Polyzois Makras Department of Endocrinology and Diabetes, 251 Hellenic Air Force & VA General Hospital, Athens, Greece

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-up can be recommended. Intralesional corticosteroid injection, low-dose irradiation or surgical curettage have been used. However, complete surgical excision is not always recommended as it may sometimes increase the healing time and/or leave a large bone

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-18-0186
Volume/Issue:
Volume 7: Issue 7
Open access