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Richard H Tuligenga

Introduction Patients with type 2 diabetes mellitus show faster cognitive decline compared with healthy subjects (1) . Numerous studies in patients with type 2 diabetes have dealt with the association between the level of glycaemic control and the

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Lukas Engler, Christian Adolf, Daniel A Heinrich, Anna-Katharine Brem, Anna Riester, Anna Franke, Felix Beuschlein, Martin Reincke, Axel Steiger and Heike Künzel

impairment and the development of dementia ( 20 ). Yagi et al . could additionally identify high plasma aldosterone as a risk factor for cognitive decline in patients with essential hypertension ( 21 ). Similar results were found in elder patients with

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Sheila Leone, Lucia Recinella, Annalisa Chiavaroli, Claudio Ferrante, Giustino Orlando, Michele Vacca, Roberto Salvatori and Luigi Brunetti

months, while in −/− mice a significant decline in cognitive function was found only at 12 months compared with 2-month-old mice. Moreover, our findings showed a decreased percentage age-related cognitive decline in −/− mice as compared to +/− controls

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Henryk F Urbanski, Kevin Mueller and Cynthia L Bethea

(SERM) supplementation on age-associated cognitive decline and activity ( 2 , 3 , 4 , 5 , 6 ). However, the monkeys in the above studies were fed a standard primate chow that was low in fat and sugar, but high in micronutrients. Therefore, it is

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Patricia Iozzo and Maria Angela Guzzardi

associated with a greater risk of premature cognitive decline, from early life to elderly age ( 16 , 17 , 18 , 19 , 20 ). Growing scientific efforts are being devoted to the identification of central mechanisms underlying the mutual reinforcement

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Andrew R Dismukes, Vanessa J Meyer, Elizabeth A Shirtcliff, Katherine P Theall, Kyle C Esteves and Stacy S Drury

between stress, aging, and health. As both DHEA and TL have been associated with a range of health outcomes that are accentuated with stress exposure, such as cognitive decline, obesity, and cardiovascular disease ( 1 , 15 ), understanding how these two

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Roberto Cosimo Melcangi, Livio Casarini, Marco Marino, Daniele Santi, Samantha Sperduti, Silvia Giatti, Silvia Diviccaro, Maria Grimoldi, Donatella Caruso, Guido Cavaletti and Manuela Simoni

31 Harman MF Martin MG . Epigenetic mechanisms related to cognitive decline during aging . Journal of Neuroscience Research 2019 [epub]. ( https://doi.org/10.1002/jnr.24436 ) 31045277 32 Bechis SK Otsetov AG Ge R Wang Z Vangel MG

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Dmitry M Davydov and Malik K Nurbekov

regulation is associated with cognitive performance and dietary preferences. For example, only higher HbA 1c or MPG was associated with cognitive decline and cognitive impairments (e.g., lower scores of visual motor speed, attention, learning, and verbal

Open access

Jairo Arturo Pinzón-Cortés, Angelina Perna-Chaux, Nicolás Steven Rojas-Villamizar, Angélica Díaz-Basabe, Diana Carolina Polanía-Villanueva, María Fernanda Jácome, Carlos Olimpo Mendivil, Helena Groot and Valeriano López-Segura

arterial disease) and microvascular diseases (neuropathy, retinopathy and neuropathy), plus many other alterations that predispose to cognitive decline and bone fragility. Diabetes is a worldwide public health issue. By 2013, the number of patients with