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effects ( 2 ). Thus, further exploration of the molecular mechanisms of GD is essential, which will be beneficial for developing new diagnostic and personalized therapeutic strategies for the disease. Circular RNAs (circRNAs) are a new type of ncRNA
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) expression was higher in PC than in PA ( 23 ). However, immunohistochemistry was used to detect the cancer- IgG , which does not apply to the preoperative diagnosis PC. Circular RNAs have recently been detectable non-invasively in peripheral blood specimens
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, circular RNAs, and lncRNAs) are reported to be differently expressed in SCAs ( 13 , 16 , 18 , 21 , 27 , 28 , 29 , 30 , 31 , 32 ). When comparing the alterations seen in the methylome with that seen in the transcriptome of SCAs, it is evident that
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: the Journal of the International Society for Oncodevelopmental Biology and Medicine 2015 36 8185 – 8191 . ( https://doi.org/10.1007/s13277-015-3498-8 ) 34 Wang N Gu Y Li L Wang F Lv P Xiong Y Qiu X . Circular RNA circMYO9B facilitates
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-015-0112-2 ) 12 Johannsen EB Just J Viuff MH Okholm TLH Pedersen SB Meyer Lauritsen K Trolle C Pedersen MGB Chang S Fedder J Sex chromosome aneuploidies give rise to changes in the circular RNA profile: a circular transcriptome-wide study of
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of Life Research 2021 . ( https://doi.org/10.1007/s11136-021-02798-1 ) 17 Liu X Du Z Yi X Sheng T Yuan J Jia J Circular RNA circANAPC2 mediates the impairment of endochondral ossification by miR-874-3p/SMAD3 signalling pathway in
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circular RNAs (circRNAs) ( 5 , 6 , 7 ). These epigenetic processes are essential for elucidating the intricate mechanisms underlying the development and progression of thyroid cancer. Furthermore, the study of these epigenetic pathways holds significant