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Robert I Menzies, Xin Zhao, Linda J Mullins, John J Mullins, Carolynn Cairns, Nicola Wrobel, Donald R Dunbar, Matthew A Bailey and Christopher J Kenyon

corticosteroid release ( 1 , 2 ). Closer analysis of acute responses has demonstrated that activation of melanocortin receptors trigger cyclic AMP synthesis, leading to the synthesis of StaR, which promotes the uptake of cholesterol into mitochondria ( 3 , 4

Open access

Giorgio Bedogni, Andrea Mari, Alessandra De Col, Sofia Tamini, Amalia Gastaldelli and Alessandro Sartorio

shown that insulin secretion (ISEC) is independently associated with triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) but not with low-density lipoprotein cholesterol (LDL-C) ( 2 ). As noted by the RISC investigators ( 2 ), most of the

Open access

Marcus Quinkler, Bertil Ekman, Claudio Marelli, Sharif Uddin, Pierre Zelissen, Robert D Murray and on behalf of the EU-AIR Investigators

pressure; waist circumference; total cholesterol; high-density lipoprotein (HDL) cholesterol and low-density lipoprotein (LDL) cholesterol; glycated haemoglobin (HbA1c); triglycerides and the proportion of patients using statins. Statistics Summary

Open access

Eric Seidel, Gudrun Walenda, Clemens Messerschmidt, Benedikt Obermayer, Mirko Peitzsch, Paal Wallace, Rohini Bahethi, Taekyeong Yoo, Murim Choi, Petra Schrade, Sebastian Bachmann, Gerhard Liebisch, Graeme Eisenhofer, Dieter Beule and Ute I Scholl

). Because SOAT catalyzes the generation of cholesterol esters from free sterol and acyl CoA ( 14 ), inhibition of its activity has been proposed to result in elevated levels of free cholesterol, ER stress and apoptosis. The molecular mechanisms of acquired

Open access

Line K Johnson, Kirsten B Holven, Njord Nordstrand, Jan R Mellembakken, Tom Tanbo and Jøran Hjelmesæth

based on whole-grain crispbread (CB) on serum levels of triacylglycerol, HDL-cholesterol, LDL-cholesterol, glucose, uric acid and BP, in morbidly obese women with PCOS. Additionally, we compared the effects of the LCD-diets on the MS, body weight, body

Open access

Ningning Gong, Cuixia Gao, Xuedi Chen, Yu Wang and Limin Tian

analysis method (North Biotechnology Research Co, Ltd, Beijing, China). Serum total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) concentrations were measured by enzymatic

Open access

Pinaki Dutta, Bhuvanesh Mahendran, K Shrinivas Reddy, Jasmina Ahluwalia, Kim Vaiphei, Rakesh K Kochhar, Prakamya Gupta, Anand Srinivasan, Mahesh Prakash, Kanchan Kumar Mukherjee, Viral N Shah, Girish Parthan and Anil Bhansali

5 Estrogen replacement 1 Median peak GH on IIH (IQR) (ng/ml) 10.2 (10–18.2) 0.6 (0.09–1.2) IGF1 (ng/ml) 129.3 (105.7–146) 32.4 (26.6–57.2) <0.001* IGF1 SDS a −0.7 (−0.6) −2.5 (0.4) 0.001* Total cholesterol (mg/dl) 186 (19.6) 212.6 (34) NS LDL (mg

Open access

David J F Smith, Hemanth Prabhudev, Sirazum Choudhury and Karim Meeran

and hydrocortisone, except for total cholesterol (TC) and low-density lipoprotein (LDL), where the values were higher in the prednisolone cohort ( 19 ). We have therefore collected data from Imperial College Healthcare NHS Trust, a tertiary centre to

Open access

V Guarnotta, C Di Stefano, A Santoro, A Ciresi, A Coppola and C Giordano

, were extracted. In addition, fasting lipids (total cholesterol (TC), HDL cholesterol (HDL-C), LDL cholesterol (LDL-C) and triglycerides (TG)), HbA1c and glycemia were obtained. The blood sample was performed about 2 h after GC administration (patients

Open access

Nicolás Crisosto, Bárbara Echiburú, Manuel Maliqueo, Marta Luchsinger, Pedro Rojas, Sergio Recabarren and Teresa Sir-Petermann

coefficients of variation were 5.3% and 8.7%, respectively. Serum glucose and lipid profile were determined by the glucose oxidase method (Biosystem). The intraassay coefficient of variation of this method was <1.2% and interassay was <2.7%. LDL cholesterol was