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Aneta Gawlik, Michael Shmoish, Michaela F Hartmann, Stefan A Wudy, Zbigniew Olczak, Katarzyna Gruszczynska and Ze’ev Hochberg

Introduction Nonsyndromic childhood obesity is associated with nonalcoholic fatty liver disease (NAFLD), a spectrum of conditions, ranging from steatosis to nonalcoholic steatohepatitis (NASH), and various degrees of fibrosis and cirrhosis ( 1

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Nicola Tufton, Lucy Shapiro, Anju Sahdev, Ajith V Kumar, Lee Martin, William M Drake, Scott A Akker and Helen L Storr

transformation ( 7 , 8 ). Approximately 72% of metastatic PPGLs in childhood are associated with SDHB mutations ( 3 ). This emphasises the importance of lifelong, regular surveillance for all children carrying SDHB mutations in an experienced centre as

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Agnieszka Bogusz, Svenja Boekhoff, Monika Warmuth-Metz, Gabriele Calaminus, Maria Eveslage and Hermann L Müller

bodies, and a + pHL: HL involving anterior hypothalamic structures, mammillary bodies and hypothalamic areas dorsal of mammillary bodies ( Fig. 1 ). Figure 1 Presurgical (A, C and E) and postsurgical (B, D and F) MRIs of three childhood

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Jing Wang, Leishen Wang, Huikun Liu, Shuang Zhang, Junhong Leng, Weiqin Li, Tao Zhang, Nan Li, Wei Li, Andrea A Baccarelli, Lifang Hou and Gang Hu

). Thus, more studies are expected to provide evidence and illustrate the impact of GDM on children’s growth and development. The present study aims to compare different indicators of childhood obesity between offspring exposed to maternal GDM and those

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Jan-Bernd Stukenborg, Kirsi Jahnukainen, Marsida Hutka and Rod T Mitchell

the testis. We will primarily focus on studies involving human and non-human primates, supported by findings from rodent studies where appropriate. Testicular development in infancy, childhood, puberty and adulthood Hormonal control of

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Sandrine Visentin, Gérard Michel, Claire Oudin, Béatrice Cousin, Bénédicte Gaborit, Inès Abdesselam, Marie Maraninchi, Marion Nowicki, René Valéro, Maxime Guye, Monique Bernard, Pascal Auquier, Hervé Chambost, Marie-Christine Alessi and Sophie Béliard

Introduction Advances in the treatment strategies and supportive care for childhood acute leukemia (AL) have resulted in marked improvements in survival, which now exceeds 80% for lymphoblastic and 60% for myeloid AL ( 1 ). However, long

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Monica F Stecchini, Zilda Braid, Candy B More, Davi C Aragon, Margaret Castro, Ayrton C Moreira and Sonir R Antonini

shown to be associated with the development of other types of cancer in adulthood, in the context of Li-Fraumeni syndrome ( 25 , 26 ). Pediatric ACTs are more commonly diagnosed in early childhood (<4 years) and predominantly affect females ( 19 , 23

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Laura van Iersel, Sarah C Clement, Antoinette Y N Schouten-van Meeteren, Annemieke M Boot, Hedi L Claahsen-van der Grinten, Bernd Granzen, K Sen Han, Geert O Janssens, Erna M Michiels, A S Paul van Trotsenburg, W Peter Vandertop, Dannis G van Vuurden, Hubert N Caron, Leontien C M Kremer and Hanneke M van Santen

Introduction Childhood brain tumor survivors (CBTS) have an increased risk of developing central hypothyroidism due to damage of the hypothalamic–pituitary (HP) region, especially after exposure to cranial radiotherapy (cRT) ( 1 , 2 ). The

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Anne Bachelot, Magaly Vialon, Amandine Baptiste, Isabelle Tejedor, Caroline Elie, Michel Polak, Philippe Touraine and the CRMERC study group

process and of a regular medical follow-up on QoL and on health status in a cohort of patients with classic and non-classic CAH diagnosed during childhood. Patients and methods Patients Patients were recruited from the registers of Pediatric

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Suma Uday, Ardita Kongjonaj, Magda Aguiar, Ted Tulchinsky and Wolfgang Högler

, Portugal, Netherlands and Serbia, three from Spain and six from Germany. Characteristics of national policies All countries except Italy (96%, 28/29) reported to have a national policy in place for vitamin D supplementation in infancy and childhood