Introduction Nonsyndromic childhood obesity is associated with nonalcoholic fatty liver disease (NAFLD), a spectrum of conditions, ranging from steatosis to nonalcoholic steatohepatitis (NASH), and various degrees of fibrosis and cirrhosis ( 1
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Aneta Gawlik, Michael Shmoish, Michaela F Hartmann, Stefan A Wudy, Zbigniew Olczak, Katarzyna Gruszczynska, and Ze’ev Hochberg
Mette Marie Baunsgaard, Anne Sophie Lind Helligsoe, Louise Tram Henriksen, Torben Stamm Mikkelsen, Michael Callesen, Britta Weber, Henrik Hasle, and Niels Birkebæk
). With more children surviving a brain tumor, it is evident that survivorship comes with a cost. Childhood brain tumor survivors have an increased risk of long-term and possibly lifelong morbidity affecting multiple organ systems ( 4 ). Compared to
Nicola Tufton, Lucy Shapiro, Anju Sahdev, Ajith V Kumar, Lee Martin, William M Drake, Scott A Akker, and Helen L Storr
transformation ( 7 , 8 ). Approximately 72% of metastatic PPGLs in childhood are associated with SDHB mutations ( 3 ). This emphasises the importance of lifelong, regular surveillance for all children carrying SDHB mutations in an experienced centre as
Sophie van Rijn, Kimberly Kuiper, Nienke Bouw, Evelien Urbanus, and Hanna Swaab
vulnerability as well as the recognition of specific targets for early intervention. The TRIXY Early Childhood Study is a longitudinal study designed to identify early neurodevelopmental risks in children with SCT. Based on studies in adolescents and adults
S C Clement, W E Visser, C A Lebbink, D Albano, H L Claahsen-van der Grinten, A Czarniecka, R P Dias, M P Dierselhuis, I Dzivite-Krisane, R Elisei, A Garcia-Burillo, L Izatt, C Kanaka-Gantenbein, H Krude, L Lamartina, K Lorenz, M Luster, R Navardauskaitė, M Negre Busó, K Newbold, R P Peeters, G Pellegriti, A Piccardo, A L Priego, A Redlich, L de Sanctis, M Sobrinho-Simões, A S P van Trotsenburg, F A Verburg, M Vriens, T P Links, S F Ahmed, and H M van Santen
will not affect disease-specific morbidity and mortality, yet may reduce treatment-induced adverse outcome. As a consequence of the rarity of the disease during childhood and adolescence, current treatment guidelines are predominantly based on the
V G Pluimakers, M van Waas, C W N Looman, M P de Maat, R de Jonge, P Delhanty, M Huisman, F U S Mattace-Raso, M M van den Heuvel-Eibrink, and S J C M M Neggers
Introduction Over the past decades, survival rates of childhood nephroblastoma and neuroblastoma have increased to respectively ~90% and ~40–95% (strongly dependent on stadium) ( 1 , 2 ). These tumours are of embryonic origin, with a peak
Ichelle Maa van Roessel, Boudewijn Bakker, Hanneke M van Santen, and Wassim Chemaitilly
Introduction Endocrine disorders affect up to 60% of childhood cancer survivors (CCS) ( 1 ). Cancer, brain tumors and their treatments have been associated with a higher risk of deficiencies in growth hormone (GH), thyroid hormone and sex
Martijn J J Finken, Aleid J G Wirix, Ines A von Rosenstiel-Jadoul, Bibian van der Voorn, Mai J M Chinapaw, Michaela F Hartmann, Joana E Kist-van Holthe, Stefan A Wudy, and Joost Rotteveel
Introduction Rates of childhood obesity have steeply increased over the past decades ( 1 ). Nowadays, an estimated number of 107.7 million children suffer from obesity worldwide ( 1 ), and approximately 20% of them progress to hypertension ( 2
Agnieszka Bogusz, Svenja Boekhoff, Monika Warmuth-Metz, Gabriele Calaminus, Maria Eveslage, and Hermann L Müller
bodies, and a + pHL: HL involving anterior hypothalamic structures, mammillary bodies and hypothalamic areas dorsal of mammillary bodies ( Fig. 1 ). Figure 1 Presurgical (A, C and E) and postsurgical (B, D and F) MRIs of three childhood
Jing Wang, Leishen Wang, Huikun Liu, Shuang Zhang, Junhong Leng, Weiqin Li, Tao Zhang, Nan Li, Wei Li, Andrea A Baccarelli, Lifang Hou, and Gang Hu
). Thus, more studies are expected to provide evidence and illustrate the impact of GDM on children’s growth and development. The present study aims to compare different indicators of childhood obesity between offspring exposed to maternal GDM and those
