of central hypogonadism in childhood and adolescence. However, an accompanying peripheral defect cannot be excluded in our female cohort, and it is likely that the unrecordable inhibin B levels (<10 pg/mL) reported in older PWS females do reflect
Search Results
Sakina Kherra, Wendy Forsyth Paterson, Filiz Mine Cizmecioglu, Jeremy Huw Jones, Mariam Kourime, Heba Hassan Elsedfy, Sameh Tawfik, Andreas Kyriakou, Mohamad Guftar Shaikh, and Malcolm David Cairns Donaldson
Nidan Qiao, Haixia Cheng, Zhaoyun Zhang, Hongying Ye, Ming Shen, Xuefei Shou, Xiaoyun Cao, Hong Chen, Xiang Zhou, Yongfei Wang, and Yao Zhao
below the reference range with insufficiently elevated thyroid-stimulating hormone. In men, central hypogonadism was diagnosed if testosterone was low in conjunction with normal or low luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In
Rui-yi Tang, Rong Chen, Miao Ma, Shou-qing Lin, Yi-wen Zhang, and Ya-ping Wang
M Libri DV Guizzardi F Guarducci E Maiolo E Pignatti E Asci R Persani L. New understandings of the genetic basis of isolated idiopathic central hypogonadism . Asian Journal of Andrology 2012 14 49 – 56 . ( doi:10
Rossella Cannarella, Andrea Crafa, Sandro La Vignera, Rosita A Condorelli, and Aldo E Calogero
, in turn, secrete AMH ( 41 ). Interestingly, AMH receptors (AMHR) have been reported in human GnRH neurons, where AMH stimulates neuron firing ( 43 ). Defective AMH signaling results in central hypogonadism ( 44 ), suggesting that normal Sertoli cell
Mikkel Andreassen, Anders Juul, Ulla Feldt-Rasmussen, and Niels Jørgensen
, we observed an abnormal relationship between total-testosterone and cfT vs the corresponding LH in the majority of patients. Thus, we speculate that the bioactivity of LH might be reduced in male patients with central hypogonadism. This is to our
H A Booij, W D C Gaykema, K A J Kuijpers, M J M Pouwels, and H M den Hertog
–15 months after stroke ( 7 ). GHD and central hypogonadism were the most frequent PDs. In 8.3% of patients, PD improved, and in 6.2%, it worsened over time. Predictors of PD were diabetes mellitus and more severe stroke (clinically and radiologically). PD
Luca Persani, Biagio Cangiano, and Marco Bonomi
combined with central hypogonadism Genetic defects inconstantly associated with CeH SOX2 184429 AD Variable hypopituitarism, pituitary hypoplasia, microphthalmia, variable learning difficulties NFKB2 164012 AD Deficient
Christine Poitou, Anthony Holland, Charlotte Höybye, Laura C G de Graaff, Sandrine Bottius, Berit Otterlei, and Maithé Tauber
. Hypogonadism was present in 98% of males and 94% of females. Both primary and central hypogonadism were present, as well as mixed forms. The major reason why individuals did not receive (adequate doses of) SHRT was for behavioral challenges. Based on our
