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Introduction Atrial fibrillation (AF) occurs in 6–28% of people with hyperthyroidism ( 1 , 2 , 3 , 4 , 5 , 6 ). Thyrotoxicosis increases the activities of thrombin, fibrinogen, factor VIII, factor IX, von Willebrand factor, and tissue
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), we hypothesized that subclinical hypothyroidism was associated with an increased LA pressure. It is well known that hyperthyroidism often causes atrial fibrillation (AF) ( 1 , 2 ), and recently, a study ( 10 ) has provided evidence supporting the
Department of Endocrinology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, China
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does to the heart and blood vessels ( 2 ). For the first time, in 2020, the European Society of Hypertension (ESH) proposed including patients with atrial fibrillation (AF) of unclear cause in PA screening ( 3 ). The incidence of AF and other
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example is a paper by Sawin et al ., which showed a low serum thyrotropin (thyroid-stimulating hormone (TSH)) concentration in people aged 60 or older to be associated with a three times higher incidence of atrial fibrillation in the subsequent decade ( 6
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infection, sepsis, pneumonia and urinary infection), acute kidney injury, atrial fibrillation and myocardial infarction. Furthermore, tight glucose control was grouped into two intensities: very tight glucose control (upper level of perioperative glucose
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ongoing risk stratification, considering not only their benefit on outcome of DTC, but also any risk associated with exogenous thyrotoxicosis, namely menopause, osteopenia or osteoporosis, age >60 years, and history of atrial fibrillation ( 17 ) ( Table 1
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Clinical Research Centre, Medical University of Bialystok, Bialystok, Poland
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.8 0 0.5 Coronary angioplasty (%) 5 5.4 0.6 Atrial fibrillation (%) 5.4 2.5 0.2 ACTH, adrenocorticotrophic hormone; CKD, chronic kidney disease; GFR, glomerular filtration rate; MACS, mild adrenal autonomous
Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Epidemiology, Aarhus University Hospital and Aarhus University, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Department of Cardiology, Aarhus University Hospital, Aarhus, Denmark
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Steno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
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Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
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, atrial fibrillation and flutter, heart failure, peripheral vascular disease, and stroke from the index (Supplementary Table 3) ( 31 , 32 , 33 ). A lookback period of 5 years has been reported to be an appropriate time period to capture relevant
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel
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Community Division, Clalit Health Services, Tel Aviv, Israel
The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children’s Medical Center of Israel, Petah Tikva, Israel
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Department of Cardiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
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Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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National Cancer Registry, Israel Center for Disease Control, Ministry of Health, Israel, Ramat Gan, Israel
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). Several small-scale studies of TC survivors with suppressed TSH showed impairment in cardiac structure ( 6 , 7 ) and function ( 8 , 9 , 10 , 11 , 12 ), as well as a prothrombotic profile ( 13 ). An increase in the prevalence of atrial fibrillation (AF
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Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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Department of Medicine O, Department of Clinical Physiology and Nuclear Medicine, Department of Clinical Physiology, Faculty of Health Sciences, Center for Functional and Diagnostic Imaging and Research, Centre of Endocrinology and Metabolism, Herlev University Hospital, Herlev Ringvej 75, Herlev DK‐2730, Denmark
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development of atrial fibrillation. In a recent large cohort from the Danish population, this effect seems to be present even among euthyroid people with serum TSH levels in the lower normal range, suggesting a dose-dependent manner of effect of slightly