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Muthiah Subramanian Department of General Medicine, TB and Pulmonary Medicine, Endocrinology, Sri Ramachandra University, 1 Ramachandra Nagar, Porur, Chennai 600116, India

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Manu Kurian Baby Department of General Medicine, TB and Pulmonary Medicine, Endocrinology, Sri Ramachandra University, 1 Ramachandra Nagar, Porur, Chennai 600116, India

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Krishna G Seshadri Department of General Medicine, TB and Pulmonary Medicine, Endocrinology, Sri Ramachandra University, 1 Ramachandra Nagar, Porur, Chennai 600116, India

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Introduction Although antithyroid drugs (ATDs) and partial thyroidectomy have established the treatment modalities, radioiodine therapy has become the primary treatment option of hyperthyroidism in Graves' disease (1, 2) . A number of interrelated

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-15-0119
Volume/Issue:
Volume 5: Issue 1
Open access
Kjersti S Bakken Women’s Clinic, Innlandet Hospital Trust, Lillehammer, Norway
Center for International Health, University of Bergen, Bergen, Norway

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Kristina Randjelovic Nermo Center for International Health, University of Bergen, Bergen, Norway
Department of Microbiology, Innlandet Hospital Trust, Lillehammer, Norway

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Bjørn Gunnar Nedrebø Department of Medicine, Haugesund Hospital, Haugesund, Norway
Department of Clinical Science, University of Bergen, Bergen, Norway

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Tim I M Korevaar Academic Center for Thyroid Diseases, Erasmus University Medical Center, Rotterdam, the Netherlands

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Tor A Strand Center for International Health, University of Bergen, Bergen, Norway
Department of Research, Innlandet Hospital Trust, Lillehammer, Norway

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criteria and indications for antithyroid drug treatments for Graves’ hyperthyroidism have remained essentially unchanged. A Norwegian government report from 1999 raised concerns regarding thyroid function in pregnancy and highlighted the need for data on

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-21-0631
Volume/Issue:
Volume 11: Issue 4
Open access
Marek Niedziela Department of Pediatric Endocrinology and Rheumatology, Institute of Pediatrics, Karol Jonscher’s Clinical Hospital, Poznan University of Medical Sciences, Poznan, Poland

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). Table 2 Adverse effects of antithyroid drugs. Adverse effects that require the immediate cessation of thionamide treatment: 1) Agranulocytosis (<500/µL; 0.2–0.5% treated), aplastic anemia (even rarer) 2) Acute hepatitis (sporadic; mainly

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-21-0191
Volume/Issue:
Volume 10: Issue 11
Open access
Stine Linding Andersen Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark
Department of Clinical Medicine, Aalborg University, Aalborg, Denmark

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Stig Andersen Department of Clinical Medicine, Aalborg University, Aalborg, Denmark
Department of Geriatrics, Aalborg University Hospital, Aalborg, Denmark

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, can be ascertained from the beginning of the 20th century with a main concern about adverse pregnancy outcomes in women suffering from severe, untreated hyperthyroidism ( 5 ). The use of antithyroid drugs (ATDs) for the treatment of hyperthyroidism

Article Type:
Review Article
DOI:
https://doi.org/10.1530/EC-20-0518
Volume/Issue:
Volume 10: Issue 2
Open access
Adriano N Cury Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil

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Verônica T Meira Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil

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Osmar Monte Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil
Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil

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Marília Marone Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil

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Nilza M Scalissi Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil

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Cristiane Kochi Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil

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Luís E P Calliari Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil

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Carlos A Longui Pediatric Endocrinology Unit, Endocrinology and Metabolism, Nuclear Medicine Laboratory, Pediatrics Department, Irmandade da Santa Casa de Misericórdia de São Paulo, 01221-020 São Paulo, Brazil

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countries, antithyroid drugs (ATDs) remain the first-line therapy (1, 2, 4, 5) , but they have several drawbacks, such as a high prevalence of side effects (20–30%), prolonged need for oral therapy, and low remission and high relapse rates during or after

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-12-0049
Volume/Issue:
Volume 2: Issue 1
Open access
Caiyan Mo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Tao Tong Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Ying Guo Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Zheng Li Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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Liyong Zhong Department of Endocrinology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

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.34 ATD, TSS 1.91 582 2.53 90.18 0.077 6.57 9.53 − ATD, antithyroid drugs; BMI, body mass index; Dmax, maximum diameter; F, female; FT3, free triiodothyronine; FT4, free thyroxine;GH, growth hormone; IGF-1, insulin-like growth

Article Type:
Research Article
Collections:
Thyroid
DOI:
https://doi.org/10.1530/EC-23-0439
Volume/Issue:
Volume 13: Issue 4
Open access
Shih-Rong Lin Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan

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Shih-Fen Chen Department of Obstetrics and Gynecology, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan

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Yu-Cih Yang Management Office for Health Data, China Medical University Hospital, Taichung, Taiwan

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Chung-Y Hsu Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan

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Yu-Chih Shen Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan
Department of Psychiatry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan
School of Medicine, Tzu Chi University, Hualien, Taiwan

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in LHID2000 were considered for inclusion in the case cohort. For a reliable diagnosis, the case cohort included only those individuals who had been treated with antithyroid drugs (propylthiouracil, thiamazole, and carbimazole), radioactive iodine

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-20-0554
Volume/Issue:
Volume 10: Issue 1
Open access
Jan Calissendorff Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

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Henrik Falhammar Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Stockholm, Sweden
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

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, Karolinska Institutet, and the Stockholm County Council. The authors want to thank Elisabeth Gramatkovski for iodine analysis. References 1 Abraham P Avenell A McGeoch SC Clark LF Bevan JS. Antithyroid drug regimen for treating

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-17-0025
Volume/Issue:
Volume 6: Issue 4
Open access
Chun-feng Lu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Wang-shu Liu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Xiao-qin Ge Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Feng Xu Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Jian-bin Su Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Xue-qin Wang Department of Endocrinology, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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Yan Wang Department of Geriatrics, Affiliated Hospital 2 of Nantong University and First People’s Hospital of Nantong City, Nantong, China

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, which may create difficulties in treating this disease ( 3 ). Treatments for GD include oral antithyroid drugs, radioactive iodine therapy (RAI), and surgery, but each treatment regimen has the possibility of side effects ( 4 ). From this statement

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0344
Volume/Issue:
Volume 10: Issue 10
Open access
Xichang Wang Department of Endocrinology and Metabolism and The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

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Xiaochun Teng Department of Endocrinology and Metabolism and The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

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Chenyan Li Department of Endocrinology and Metabolism and The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

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Yushu Li Department of Endocrinology and Metabolism and The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

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Jing Li Department of Endocrinology and Metabolism and The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

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Weiping Teng Department of Endocrinology and Metabolism and The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

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Zhongyan Shan Department of Endocrinology and Metabolism and The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

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Yaxin Lai Department of Endocrinology and Metabolism and The Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, The First Hospital of China Medical University, Shenyang, Liaoning, People’s Republic of China

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VM . Antithyroid drugs-the most common treatment for Graves’ disease in the United States: a nationwide population-based study . Thyroid 2016 26 1144 – 1145 . ( https://doi.org/10.1089/thy.2016.0222 ) 17 Azizi F Amouzegar A Tohidi M

Article Type:
Research Article
DOI:
https://doi.org/10.1530/EC-21-0340
Volume/Issue:
Volume 10: Issue 9
Open access