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G Giuffrida, F Ferraù, R Laudicella, O R Cotta, E Messina, F Granata, F F Angileri, A Vento, A Alibrandi, S Baldari and S Cannavò

and the third by NFPT. Tumor progression was stopped only in the NFPT patient, who was followed up over 40 months ( 14 ). Out of six patients with aggressive pituitary adenomas, two were treated with 177 Lu-DOTATATE (one and two cycles, respectively

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Adrian F Daly, David A Cano, Eva Venegas-Moreno, Patrick Petrossians, Elena Dios, Emilie Castermans, Alvaro Flores-Martínez, Vincent Bours, Albert Beckers and Alfonso Soto-Moreno

neurosurgery, medical therapy and radiotherapy can be needed to treat pituitary adenomas ( 4 , 5 , 6 , 7 ). There is an increased likelihood of aggressive pituitary adenoma characteristics (early age at diagnosis, large tumor size, increased invasiveness

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Morten Winkler Møller, Marianne Skovsager Andersen, Christian Bonde Pedersen, Bjarne Winther Kristensen and Frantz Rom Poulsen

Ieva A Rotondo F Syro LV Cusimano MD Kovacs K. Aggressive pituitary adenomas – diagnosis and emerging treatments . Nature Reviews Endocrinology 2014 10 423 – 435 . ( https://doi.org/10.1038/nrendo.2014.64 ) 24821329 10.1038/nrendo