.001). Despite ovarian volume being larger in PCOS patients than in controls in each five-year range age group, from ≤19 years to 39 years ( P < 0.001 for all strata comparisons), the tendency analyses showed that the ovarian volume presented a non
Sebastião Freitas de Medeiros, Márcia Marly Winck Yamamoto, Matheus Antônio Souto de Medeiros, Bruna Barcelo Barbosa, José Maria Soares Junior and Edmund Chada Baracat
Volha V Zhukouskaya, Anya Rothenbuhler, Annamaria Colao, Carolina Di Somma, Peter Kamenický, Séverine Trabado, Dominique Prié, Christelle Audrain, Anna Barosi, Christèle Kyheng, Anne-Sophie Lambert and Agnès Linglart
and methods The entire patients’ follow-up period was from birth till the age of 20 years and was divided into five sub-periods defining age groups from 0 to 4. Group 0 included the parameters at birth, and groups 1, 2, 3, and 4 comprised the follow
Shilpa Lingaiah, Laure Morin-Papunen, Terhi Piltonen, Inger Sundström-Poromaa, Elisabet Stener-Victorin and Juha S Tapanainen
-related changes of RBP4 between different age groups. Pearson’s correlation coefficients were used to assess the correlation between RBP4 and different variables, and adjustment for age and BMI was carried out by way of partial correlation analyses. Values of P
Manjeetkaur Sehemby, Prachi Bansal, Vijaya Sarathi, Ashwini Kolhe, Kanchan Kothari, Swati Jadhav-Ramteke, Anurag R Lila, Tushar Bandgar and Nalini S Shah
manifestations. Hyperestrogenic manifestations are age dependent. Prepubertal girls usually present with gonadotropin-independent isosexual precocious puberty whereas women in reproductive age group or postmenopausal age present with irregular and excessive
Adriano N Cury, Verônica T Meira, Osmar Monte, Marília Marone, Nilza M Scalissi, Cristiane Kochi, Luís E P Calliari and Carlos A Longui
tremendous controversy regarding the most appropriate treatment schedule for this age group (3) . No strategy targets the underlying autoimmunity, and the control of thyroid hyperfunction is usually achieved by the induction of hypothyroidism. In many
Miranda Scharff, Chantal Maria Wiepjes, Maartje Klaver, Thomas Schreiner, Guy T’Sjoen and Martin den Heijer
grip strength (−1.2 kg) occurred in the last 3 months, while in transmen 49% of the increase (+3.0 kg) occurred in the first 3 months. Change in grip strength did not vary between different age groups ( Fig. 3A ), different BMI groups ( Fig. 3B ) and
Mirjana Kocova, Vesna Janevska and Violeta Anastasovska
-classic (NC). In the 30 males analyzed for this study in the period 2001–2016, the following disease forms were noted: SW in 16 (53.3%), SV in 9 (30%) and NC in 5 (16.7%). From 2005, we have systematically followed 25 boys in the age group 4–18 years during a
Malachi J McKenna, Barbara F Murray, Myra O'Keane and Mark T Kilbane
The Institute of Medicine 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D specified higher intakes for all age groups compared to the 1997 report, but also cautioned against spurious claims about an epidemic of vitamin D deficiency and against advocates of higher intake requirements. Over 40 years, we have noted marked improvement in vitamin D status but we are concerned about hypervitaminosis D.
We sought to evaluate the 25-hydroxyvitamin D (25OHD) trend over 20 years.
We retrieved all results of serum 25OHD from 1993 to 2013 (n=69 012) that was trimmed to one sample per person (n=43 782). We conducted a time series analysis of the monthly averages for 25OHD using a simple sequence chart and a running median smoothing function. We modelled the data using univariate auto-regressive integrated moving average (ARIMA) and forecast 25OHD levels up to 2016.
The time series sequence chart and smoother function demonstrated a steady upward trend with seasonality. The yearly average 25OHD increased from 36.1 nmol/l in 1993 to 57.3 nmol/l in 2013. The ARIMA model was a good fit for the 25OHD time series; it forecasted monthly average 25OHD up to the end of 2016 with a positive stationary R 2 of 0.377.
Vitamin D status improved over the past 40 years, but there remains a dual problem: there are groups at risk of vitamin D deficiency who need public health preventative measures; on the other hand, random members of the population are taking unnecessarily high vitamin D intakes for unsubstantiated claims.
Andrea Mazurat, Andrea Torroni, Jane Hendrickson-Rebizant, Harbinder Benning, Richard W Nason and K Alok Pathak
, 96.8% (95% CI, 93.1–98.5%) for patients in the age group of 45–54 years, 85.8% (95% CI, 78.7–90.7%) for patients in the age group of 55–64 years, and 74.0% (95% CI, 70.0–79.8%) for patients older than 65 years. Figure 1 shows no significant
K E Lines, R P Vas Nunes, M Frost, C J Yates, M Stevenson and R V Thakker
cells, which were identified in control and treated mice of all age groups. Apoptosis was evaluated using the ApopTag Fluorescein Direct In Situ Apoptosis Detection Kit (Millipore), which utilises terminal deoxynucleotidyl transferase (TdT) to detect