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research. Since only scarce information is available concerning the preconceptional risk determination of pregnancy complications in PCOS patients, we here focus on afamin, an easily determinable biomarker that may indicate IR in pre-pregnant PCOS
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Department of Gynecology and Obstetrics, Division of Genetic Epidemiology, Vitateq Biotechnology GmbH, University of Duisburg-Essen, D-45122 Essen, Germany
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)-inhibiting parameter (11) . The previously described vitamin E-binding protein afamin may play a role in oxidative stress-related anti-apoptotic cellular processes (12) . Vitamin E is an important anti-oxidant and protects from oxidative stress. Afamin was
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and 9, vascular endothelial growth factor, isoforms of apolipoprotein A-1 and haptoglobin and afamin have been identified ( 39 , 40 , 41 ). Their usefulness as biomarkers should be established in future studies. GH doping detection strategies have