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, 6 ). Patients with PPGL may have more serious cardiovascular complications (even life-threatening ones, such as arrhythmias, myocardial infarction or heart failure), compared to patients with essential hypertension (EH) ( 7 ). Adrenalectomy also
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during adrenalectomy for pheochromocytomas, including rapid and severe blood pressure fluctuations that greatly increase the risk of major morbidity ( 7 ). Anesthetic induction, intraoperative tumor handling and accidental squeezing of the tumor can
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Department and Graduate Institute of Forensic Medicine, National Taiwan University College of Medicine, Taipei, Taiwan
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studies (computed tomography (CT) or magnetic resonance imaging (MRI)). Adrenalectomy has consequently been established as the treatment of choice for unilateral disease. Recently, there has been a growing focus on a special group with cortisol co
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Medicine Department, Basque Country University, Bilbao, Spain
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CIBEROBN, Madrid, Spain
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Instituto de Investigación Biomédica Ramón y Cajal (IRYCIS), Madrid, Spain
University of Alcalá, Madrid, Spain
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study was to compare the characteristics of PA that are present at diagnosis and during follow-up, including the results in adrenal venous sampling (AVS) and adrenalectomy, in elderly patients (≥65 years) and younger patients than 65 years old, to
National Institute of Endocrinology CI Parhon, Bucharest, Romania
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National Institute of Endocrinology CI Parhon, Bucharest, Romania
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National Institute of Endocrinology CI Parhon, Bucharest, Romania
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eventually develop bilateral tumors but are followed regularly ( 10 , 11 ). The most frequently surgery technique used by surgeon is total adrenalectomy. Many patients develop the second pheochromocytoma several years after the first unilateral tumor was
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depression ( 4 , 5 ). Generally, bilateral PA is treated with mineralocorticoid receptor (MR) antagonists, while unilateral PA is managed with unilateral adrenalectomy ( 6 ). Studies have found better cardiovascular events and HRQoL outcomes following
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Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland
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higher incidence of postsurgical disease and increased aldosterone production from the remaining adrenal ( 8 , 10 , 12 , 13 ). This indicates the need for follow-up even when initial adrenalectomy results imply a cure. The gold standard for
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
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. Patients with a histological diagnosis of pheochromocytoma or paraganglioma but not pretreated with PBZ were excluded from the dataset. In addition, we included 34 control subjects who underwent laparoscopic adrenalectomy during 2011–2015 at the same
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than among those with essential hypertension (EH) ( 3 ). In addition, severe arterial stiffness is associated with the absence of complete clinical success in lateralized PA after adrenalectomy (ADX) ( 4 ). Endothelial dysfunction is recognized as a
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CT images. Slight, early enhancement was seen in the postcontrast images in all of the patients. All of the AS patients underwent operative resection by open adrenalectomy (five patients) and laparoscopy (the remaining eight patients). Surgical