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Monika Karczewska-Kupczewska, Agnieszka Nikołajuk, Radosław Majewski, Remigiusz Filarski, Magdalena Stefanowicz, Natalia Matulewicz and Marek Strączkowski

catalyzed by the enzyme adipose triglyceride lipase (ATGL), encoded by PNPLA2 . Diacylglycerol is further hydrolyzed to monoacylglycerol and fatty acid with hormone-sensitive lipase (HSL), encoded by LIPE , and monoacylglycerol is ultimately hydrolyzed to

Open access

Peter Wolf, Yvonne Winhofer, Martin Krššák and Michael Krebs

dysfunction and dysregulation of gene expression ( 20 ). Animal models impressively demonstrate the importance of a well-balanced interplay between lipid storage and lipolysis in cardiomyocytes, since mice lacking adipose triglyceride lipase (ATGL) develop

Open access

Nikolaj Rittig, Mads Svart, Niels Jessen, Niels Møller, Holger J Møller and Henning Grønbæk

epinephrine) stimulate lipolysis through the actions of adipose triglyceride lipase and hormone-sensitive lipase (HSL), which are rate-limiting enzymes in the conversion of triglycerides into glycerol and FFA. Increased rates of lipolysis elevate circulating