Division of General Medicine, Istituto Auxologico Italiano, IRCCS, S. Giuseppe Hospital, Piancavallo di Oggebbio (VB), Italy
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Division of General Medicine, Istituto Auxologico Italiano, IRCCS, S. Giuseppe Hospital, Piancavallo di Oggebbio (VB), Italy
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Division of Endocrinology, Diabetology and Metabolism, Department of Medical Sciences, University of Turin, Turin, Italy
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). Although the pathways linking obesity and IR to thyroid cancer remain largely unknown, a potential role for insulin, growth hormone (GH) secretagogues and adipokines has been postulated ( 10 ). Insulin not only regulates cell metabolism but also stimulates
Department of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, China
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atherosclerosis (AS) was reported in a large population-based study ( 2 , 3 ). Multiple lines of evidence have shown that adipokines ( 4 ), endothelial dysfunction ( 5 ) and dyslipidemia ( 6 ) play a central role in the development of AS, but the relationship
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Introduction It has been shown that the levels of different adipokines, such as leptin, adiponectin, resistin, vaspin, omentin-1 and RBP4 are higher in women than those in men ( 1 , 2 , 3 , 4 , 5 , 6 ), and that estrogens stimulate
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Department of Obstetrics and Gynaecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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pathogenesis of PCOS ( 5 , 6 , 7 ), it is not clear whether they have a direct association with PCOS. Adipose tissue acts as an endocrine organ secreting various adipokines including retinol-binding protein 4 (RBP4), which is mainly synthesised by hepatocytes
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( 12 , 13 ). Hence, there is need to predict and detect GD earlier in pregnancy in order to limit the exposure to impaired glucose metabolism. Investigating the role of adipokines associated with the pathophysiology of GD has gained interest ( 14 , 15
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Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada
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Introduction After characterisation as an adipokine by our group in 2007, research concerning chemerin and its relationship to obesity has risen steadily. Chemerin is secreted as an inactive precursor prochemerin, which undergoes processing at
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Reproductive Biology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
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Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
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-like factors called adipokines. Adipokines are a kind of cytokine that contributes to energy metabolism, inflammation, immunity, and angiogenesis, as well as, reproductive maturity and fertility ( 6 , 7 , 8 , 9 ). Regarding the latter effect, it has been
Department of Clinical Medicine, Gansu University of Chinese Medicine, Lanzhou, Gansu, China
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DZHK (German Centre for Cardiovascular Research), Greifswald, Germany
DZD (German Center for Diabetes Research), Greifswald, Germany
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Institute and Policlinic for Radiology and Interventional Radiology, University Hospital, Carl-Gustav-Carus University Dresden, Dresden, Germany
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DZHK (German Centre for Cardiovascular Research), Greifswald, Germany
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DZHK (German Centre for Cardiovascular Research), Greifswald, Germany
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DZHK (German Centre for Cardiovascular Research), Greifswald, Germany
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on the role of adipose tissue as an endocrine organ that produces a multitude of metabolically active hormones, so-called adipokines, which are known to be involved in the regulation of glucose and lipid metabolism, food intake and inflammation ( 4
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-Golabi-Behmel Syndrome (SGBS) preadipocytes followed by investigating the impact of DEHP on the ECS as an endocrine modulator of the adipokine system. Materials and methods Chemicals DEHP was dissolved in dimethyl sulfoxide (DMSO), both purchased from Sigma