Felix Haglund
Felix Haglund
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Felix Haglund in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Felix Haglund in
Google Scholar
PubMed
Gustaf Rosin
Gustaf Rosin
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Gustaf Rosin in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Gustaf Rosin in
Google Scholar
PubMed
Inga-Lena Nilsson
Inga-Lena Nilsson
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Inga-Lena Nilsson in
Google Scholar
PubMed
Search for other papers by Inga-Lena Nilsson in
Google Scholar
PubMed
C Christofer Juhlin
C Christofer Juhlin
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by C Christofer Juhlin in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by C Christofer Juhlin in
Google Scholar
PubMed
Ylva Pernow
Ylva Pernow
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Ylva Pernow in
Google Scholar
PubMed
Search for other papers by Ylva Pernow in
Google Scholar
PubMed
Sophie Norenstedt
Sophie Norenstedt
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Sophie Norenstedt in
Google Scholar
PubMed
Search for other papers by Sophie Norenstedt in
Google Scholar
PubMed
Andrii Dinets
Andrii Dinets
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Andrii Dinets in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Andrii Dinets in
Google Scholar
PubMed
Catharina Larsson
Catharina Larsson
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Catharina Larsson in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Catharina Larsson in
Google Scholar
PubMed
Johan Hartman
Johan Hartman
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Johan Hartman in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Johan Hartman in
Google Scholar
PubMed
Anders Höög
Anders Höög
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Anders Höög in
Google Scholar
PubMed
Department of Oncology–Pathology, Cancer Centre Karolinska, Department of Biosciences and Nutrition, Department of Molecular Medicine and Surgery, Department of Surgery #4, Karolinska Institutet, Stockholm, Sweden
Search for other papers by Anders Höög in
Google Scholar
PubMed
slide) were scored as heterogeneous (‘mix’). Quantification of nuclear staining intensity was performed as described previously for all slides (24) . In short, digitalised images were analysed using the Visiopharm Tissuemorph Digital Pathology
Annieke C G van Baar
Annieke C G van Baar
Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands
Search for other papers by Annieke C G van Baar in
Google Scholar
PubMed
Search for other papers by Annieke C G van Baar in
Google Scholar
PubMed
Andrei Prodan
Andrei Prodan
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Search for other papers by Andrei Prodan in
Google Scholar
PubMed
Search for other papers by Andrei Prodan in
Google Scholar
PubMed
Camilla D Wahlgren
Camilla D Wahlgren
Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Camilla D Wahlgren in
Google Scholar
PubMed
Search for other papers by Camilla D Wahlgren in
Google Scholar
PubMed
Steen S Poulsen
Steen S Poulsen
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Steen S Poulsen in
Google Scholar
PubMed
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Steen S Poulsen in
Google Scholar
PubMed
Filip K Knop
Filip K Knop
Center for Diabetes Research, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Filip K Knop in
Google Scholar
PubMed
Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Search for other papers by Filip K Knop in
Google Scholar
PubMed
Albert K Groen
Albert K Groen
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Department of Laboratory Medicine, University of Groningen, University Medical Center, Groningen, the Netherlands
Search for other papers by Albert K Groen in
Google Scholar
PubMed
Department of Laboratory Medicine, University of Groningen, University Medical Center, Groningen, the Netherlands
Search for other papers by Albert K Groen in
Google Scholar
PubMed
Jacques J Bergman
Jacques J Bergman
Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands
Search for other papers by Jacques J Bergman in
Google Scholar
PubMed
Search for other papers by Jacques J Bergman in
Google Scholar
PubMed
Max Nieuwdorp
Max Nieuwdorp
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Department of Internal Medicine, VUMC Free University, Amsterdam, the Netherlands
Wallenberg Laboratory, Sahlgrenska Hospital, University of Gothenburg, Gothenburg, Sweden
Search for other papers by Max Nieuwdorp in
Google Scholar
PubMed
Department of Internal Medicine, VUMC Free University, Amsterdam, the Netherlands
Wallenberg Laboratory, Sahlgrenska Hospital, University of Gothenburg, Gothenburg, Sweden
Search for other papers by Max Nieuwdorp in
Google Scholar
PubMed
Evgeni Levin
Evgeni Levin
Department of Vascular Medicine, Academic Medical Center, Amsterdam, the Netherlands
Horaizon BV, Delft, the Netherlands
Search for other papers by Evgeni Levin in
Google Scholar
PubMed
Horaizon BV, Delft, the Netherlands
Search for other papers by Evgeni Levin in
Google Scholar
PubMed
enteroendocrine cells was evaluated from biopsy slide sections based on immunohistochemical staining ( Fig. 1 ). Digital images of biopsy slides were obtained using Aperio ScanScope scanner with a 20× objective. The newCAST system (Visiopharm, Hørsholm, Denmark
