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Jana Ernst, Urszula Grabiec, Kathrin Falk, Faramarz Dehghani and Kristina Schaedlich

-Golabi-Behmel Syndrome (SGBS) preadipocytes followed by investigating the impact of DEHP on the ECS as an endocrine modulator of the adipokine system. Materials and methods Chemicals DEHP was dissolved in dimethyl sulfoxide (DMSO), both purchased from Sigma

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Michaela Keuper

contribution of OXPHOS to total ATP production increases to 45–73% in human adipocytes ( 95 , 97 ). Comparing mitochondrial oxygen consumption rates (OCRs) revealed four- to five-fold higher OCR in adipocytes as compared with preadipocytes (SGBS and primary

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P G Murray, D Hanson, T Coulson, A Stevens, A Whatmore, R L Poole, D J Mackay, G C M Black and P E Clayton

–Golabi–Behmel syndrome (SGBS). GPC3 interacts with IGF-II and it was initially hypothesised that GPC3 binds to and sequesters IGF-II; thus the overgrowth in SGBS is caused by increased availability of IGF-II (37) . More recent data on mouse indicate that the overgrowth

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Carolina Inda, Natalia G Armando, Paula A dos Santos Claro and Susana Silberstein

Tarrasch J Thal DM Furness SGB Christopoulos G Coudrat T Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. Nature 2017 546 118 – 123 . ( doi:10.1038/nature22327 )  73 Rosenbaum DM Rasmussen SG Kobilka