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Guoquan Zhu, Yuying Deng, Liqin Pan, Wei Ouyang, Huijuan Feng, Juqing Wu, Pan Chen, Jing Wang, Yanying Chen and Jiaxin Luo

significantly reduces sodium-iodide symporter (NIS) expression and radioiodine uptake ability and influences RAI therapy to the point of causing RAI-refractory PTC. Jiao et al . ( 16 ) designed their research concerning RAI therapy and PTC with the BRAF V600E

Open access

Adriano N Cury, Verônica T Meira, Osmar Monte, Marília Marone, Nilza M Scalissi, Cristiane Kochi, Luís E P Calliari and Carlos A Longui

surgical procedure that can effect complications, depending on the surgeon's experience (1) . Radioactive iodine (RAI) therapy has been used frequently, especially in the USA (7) , as an alternative first-line therapy to surgery and ATDs. The incidence

Open access

Catarina Tavares, Maria João Coelho, Catarina Eloy, Miguel Melo, Adriana Gaspar da Rocha, Ana Pestana, Rui Batista, Luciana Bueno Ferreira, Elisabete Rios, Samia Selmi-Ruby, Bruno Cavadas, Luísa Pereira, Manuel Sobrinho Simões and Paula Soares

analysis, in a large series of primary thyroid carcinomas and looked for possible associations with some clinicopathological and molecular features, as well as to the response to RAI therapy and outcome. In order to validate our results of SLC5A5 mRNA

Open access

Joanna Klubo-Gwiezdzinska, John Costello Jr, Kirk Jensen, Aneeta Patel, Rok Tkavc, Douglas Van Nostrand, Kenneth D Burman, Leonard Wartofsky and Vasyl Vasko

(RAI) after surgery may be (1) remnant ablation; (2) adjuvant therapy (to decrease risk of recurrence and disease-specific mortality, by destroying suspected but unproven metastatic disease) or (3) RAI therapy (to treat known persistent disease). In

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Kristine Zøylner Swan, Steen Joop Bonnema, Marie Louise Jespersen and Viveque Egsgaard Nielsen

, body mass index, thyroid function tests, anti-TPO antibodies, treatment with thyroid hormone supplements, previous radioiodine (RAI) therapy, 99m Tc-scintigraphy (if available), positron emission tomography (if available), FNAB results according to the

Open access

Joana Simões-Pereira, Daniel Macedo and Maria João Bugalho

the medical files. The prognostic value of unifocality or multifocality of metastases is still not clearly established ( 19 ). Iodine uptake by brain metastases is infrequent (up to 17% ( 19 , 20 , 21 )) and, therefore, RAI therapy is not

Open access

Ana Carolina de Jesus Paniza, Thais Biude Mendes, Matheus Duarte Borges Viana, Débora Mota Dias Thomaz, Paula B O Chiappini, Gabriel A Colozza-Gama, Susan Chow Lindsey, Marcos Brasilino de Carvalho, Venâncio Avancini Ferreira Alves, Otavio Curioni, André Uchimura Bastos and Janete Maria Cerutti

benefit from lobectomy ( 12 ). It was projected that patients with tumors diagnosed with NIFTP are unlikely to benefit from complementation thyroidectomy, RAI therapy or intense follow-up, thus leading to lower complication rates associated with total