Search Results

You are looking at 1 - 10 of 12 items for :

Clear All
Open access

G Giuffrida, F Ferraù, R Laudicella, O R Cotta, E Messina, F Granata, F F Angileri, A Vento, A Alibrandi, S Baldari and S Cannavò

receptor radionuclide therapy (PRRT) ( 7 ). The expression of different subtypes of somatostatin receptors (SSTR, mainly 1, 2 and 5 subtype) on PT cells constitute the pathophysiological basis of their treatment with first generation (octreotide, lanreotide

Open access

Benjamin G Challis, Andrew S Powlson, Ruth T Casey, Carla Pearson, Brian Y Lam, Marcella Ma, Deborah Pitfield, Giles S H Yeo, Edmund Godfrey, Heok K Cheow, V Krishna Chatterjee, Nicholas R Carroll, Ashley Shaw, John R Buscombe and Helen L Simpson

insulinoma with severe refractory hypoglycaemia, in whom PRRT with [ 177 Lu]-octreotate successfully controlled hypoglycaemia. Finally, in a subset of stage I insulinoma, whole-exome sequencing of tumour DNA was performed, aiming to identify somatic mutations

Open access

Alberto Bongiovanni, Federica Recine, Flavia Foca, Valentina Fausti, Nada Riva, Greta Fabbri, Stefano Severi, Chiara Liverani, Alessandro De Vita, Chiara Spadazzi, Giacomo Miserocchi, Laura Mercatali, Dino Amadori and Toni Ibrahim

(PRRT) in 23 (15.9%) and chemotherapy in 36 (24.8%). Seven (4.8%) patients did not undergo first-line treatment because of poor clinical conditions ( Fig. 1 ). Interventional radiological treatments (transarterial embolization or radiofrequency ablation

Open access

Ravikumar Shah, Anurag R Lila, Ramteke-Swati Jadhav, Virendra Patil, Abhishek Mahajan, Sushil Sonawane, Puja Thadani, Anil Dcruz, Prathamesh Pai, Munita Bal, Subhada Kane, Nalini Shah and Tushar Bandgar

after peptide receptor radionuclide therapy (PRRT). Histopathologic findings revealed phosphaturic mesenchymal tumor mixed connective tissue type (PMTMCT) in four patients, while the remaining three patients had PMT-OF (ossifying fibroma like

Open access

Kjell Oberg, Eric Krenning, Anders Sundin, Lisa Bodei, Mark Kidd, Margot Tesselaar, Valentina Ambrosini, Richard P Baum, Matthew Kulke, Marianne Pavel, Jaroslaw Cwikla, Ignat Drozdov, Massimo Falconi, Nicola Fazio, Andrea Frilling, Robert Jensen, Klaus Koopmans, Tiny Korse, Dik Kwekkeboom, Helmut Maecke, Giovanni Paganelli, Ramon Salazar, Stefano Severi, Jonathan Strosberg, Vikas Prasad, Aldo Scarpa, Ashley Grossman, Annemeik Walenkamp, Mauro Cives, Irene Virgolini, Andreas Kjaer and Irvin M Modlin

of radioactive somatostatin analogs ( 10 ). Strategies include somatostatin receptor agonists, ‘targeted’ agents (mTOR inhibitors and VEGF antagonists), immunotherapy (interferon), cytotoxic chemotherapy, peptide receptor radionuclide therapy (PRRT

Open access

Anna Malczewska, Magdalena Witkowska, Karolina Makulik, Agnes Bocian, Agata Walter, Joanna Pilch-Kowalczyk, Wojciech Zajęcki, Lisa Bodei, Kjell Oberg and Beata Kos-Kudła

-SSA-PET/CT, has improved the sensitivity of NET detection ( 15 ), especially in extra-hepatic localization. It has benefit in the assessment of eligibility for peptide receptor radionuclide therapy (PRRT) and somatostatin analogs (SSAs). Its accuracy, however, is

Open access

Ashley K Clift, Omar Faiz, Robert Goldin, John Martin, Harpreet Wasan, Marc-Olaf Liedke, Erik Schloericke, Anna Malczewska, Guido Rindi, Mark Kidd, Irvin M Modlin and Andrea Frilling

bowel resection ( n  = 3) or right hemicolectomy ( n  = 1). Additional treatment modalities employed in our cohort included Lutetium 177 peptide receptor radionuclide therapy (PRRT) ( n  = 15), somatostatin analogues ( n  = 18), transarterial

Open access

Samira M Sadowski, Emanuel Christ, Benoit Bédat, Attila Kollár, Wolfram Karenovics, Aurel Perren, Frédéric Triponez and on behalf of the SwissNET registry

days at 30 mg. One of them underwent sequentially a combination of carboplatin and etoposide therapy, external beam radiation and as alternative treatment modality two cycles of peptide receptor radionuclide therapy (PRRT; 177-Lutetium-DOTATOC) with

Open access

Kranti Khadilkar, Vijaya Sarathi, Rajeev Kasaliwal, Reshma Pandit, Manjunath Goroshi, Gaurav Malhotra, Abhay Dalvi, Ganesh Bakshi, Anil Bhansali, Rajesh Rajput, Vyankatesh Shivane, Anurag Lila, Tushar Bandgar and Nalini S Shah

Lung nodule Single skeletal metastasis: humerus Lung nodule; axillary lymph nodes; multiple skeletal sites Negative Metastatectomy of lung nodule; 3 cycles of PRRT; static disease; no progression F/50 Thoracic sPGL + abdominal sPGL 9

Open access

Yang Lv, Ning Pu, Wei-lin Mao, Wen-qi Chen, Huan-yu Wang, Xu Han, Yuan Ji, Lei Zhang, Da-yong Jin, Wen-Hui Lou and Xue-feng Xu

very rapidly during the past two decades ( 22 ), PRRT and LAR prove to have a place for palliative purposes in patients with NEC. However, data regarding the specific effectiveness of various therapies derive from case reports and small retrospective