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in GDM such as 8-isoprostane (8IsoP), TNF-α, and IL-10 have been studied in a very limited number of reports, in which the results are contradictory, though some showed higher levels of oxidative stress markers in pregnancies with GDM ( 9 , 10 ). P-selectin
Department of Endocrinology and Diabetes, Pakistan Kidney and Liver Institute and Research Centre, Knowledge City, Lahore, Pakistan
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Division of Bone Diseases, Geneva University Hospitals and Faculty of Medicine, University of Geneva, Geneva, Switzerland
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treatment with exenatide resulted in reductions in serum ICAM-1, p-selectin and e-selectin, although no pronounced changes were seen in endothelial function ( 25 ). Empagliflozin is a sodium-glucose cotransporter 2 (SGLT-2) inhibitor used in the treatment
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://doi.org/10.3390/ijms20205214 ) 25 Petramala L Iacobellis G Carnevale R Marinelli C Zinnamosca L Concistrè A Galassi M Iannucci G Lucia P Pignatelli P Enhanced soluble serum CD40L and serum P-selectin levels in primary aldosteronism
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intracellular adhesion molecule 1 (ICAM-1) by 22% and 20%, respectively ( Fig. 2A ). Vascular adhesion molecule was also reduced by 50% and 43%, respectively ( Fig. 2B ). The levels of other adhesion molecules, P-selectin and Endothelin-1 (ET-1), remained