Feifei Cheng
Feifei Cheng
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Noel Yat Hey Ng
Noel Yat Hey Ng
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Claudia Ha Ting Tam
Claudia Ha Ting Tam
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Yuying Zhang
Yuying Zhang
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Cadmon King Poo Lim
Cadmon King Poo Lim
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Guozhi Jiang
Guozhi Jiang
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Alex Chi Wai Ng
Alex Chi Wai Ng
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Tiffany Tse Ling Yau
Tiffany Tse Ling Yau
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Lai Ping Cheung
Lai Ping Cheung
Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, Hong Kong
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Aimin Xu
Aimin Xu
Department of Medicine, Li Ka Shing (LKS) Faculty of Medicine, University of Hong Kong, Hong Kong, Hong Kong
State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, Hong Kong
Department of Pharmacy and Pharmacology, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, Hong Kong
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State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, Hong Kong
Department of Pharmacy and Pharmacology, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, Hong Kong
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Juliana C N Chan
Juliana C N Chan
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Hong Kong, Hong Kong
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Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Hong Kong, Hong Kong
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Ronald C W Ma
Ronald C W Ma
Department of Medicine and Therapeutics The Chinese University of Hong Kong, Hong Kong, Hong Kong
Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Hong Kong, Hong Kong
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Hong Kong Institute of Diabetes and Obesity, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, Hong Kong
Chinese University of Hong Kong-Shanghai Jiao Tong University Joint Research Centre in Diabetes Genomics and Precision Medicine, Hong Kong, Hong Kong
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) family, FGF19 and FGF21, have been shown to be associated with obesity and diabetes ( 10 , 11 , 12 ). Moreover, serum FGF21 can predict the development of T2DM in the normal population, as well as being associated with incident coronary heart disease
Anru Wang
Anru Wang
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Department of Pediatrics, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Department of Pediatrics, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, China
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Xueqin Yan
Xueqin Yan
Department of Pediatrics, Boai Hospital of Zhongshan, Zhongshan, China
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Cai Zhang
Cai Zhang
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Caiqi Du
Caiqi Du
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Wenjun Long
Wenjun Long
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Di Zhan
Di Zhan
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Xiaoping Luo
Xiaoping Luo
Department of Pediatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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. Recent clinical and animal studies have reported that FGF19 and FGF21 are associated with obesity and T2DM ( 2 , 3 ). FGF19 and FGF21 suppress triglyceride and glucose syntheses, meanwhile inducing glycogenesis and fatty acid oxidation in the liver
Huixing Liu
Huixing Liu
Department of Cardiovascular Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
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Daoquan Peng
Daoquan Peng
Department of Cardiovascular Medicine, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China
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A1; SRB1, scavenger receptor b1; FGF19/21, fibroblast growth factors 19/21; HMG-COA, 3-hydroxy-3-methyl glutaryl coenzyme A; ACC, acetyl-CoA carboxylase; FAS, fatty acid synthase; CPT1A, carnitine palmitoyltransferase Iα; WAT, white adipose tissue
Karim Gariani
Karim Gariani
Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
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Geneviève Drifte
Geneviève Drifte
Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
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Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
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Irène Dunn-Siegrist
Irène Dunn-Siegrist
Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
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Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
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Jérôme Pugin
Jérôme Pugin
Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
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Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
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François R Jornayvaz
François R Jornayvaz
Service of Endocrinology, Laboratory of Intensive Care, Department of Microbiology and Molecular Medicine, Diabetes, Hypertension and Nutrition
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Introduction Fibroblast growth factor 21 (FGF21) is a member of the FGF superfamily, consisting of FGF19, FGF21, and FGF23 (1, 2, 3, 4) . Because they lack the conventional FGF-heparin-binding domain, these FGFs can escape the body's vast
Helle Keinicke
Helle Keinicke
Insulin and Device Trial Operations, Novo Nordisk A/S, Søborg, Denmark
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Gao Sun
Gao Sun
Pharmacology and Histopathology, Novo Nordisk A/S, China
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Caroline M Junker Mentzel
Caroline M Junker Mentzel
Department of Experimental Animal Models, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark
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Merete Fredholm
Merete Fredholm
Department of Veterinary Clinical and Animal Science, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark
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Linu Mary John
Linu Mary John
Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark
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Birgitte Andersen
Birgitte Andersen
Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark
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Kirsten Raun
Kirsten Raun
Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark
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Marina Kjaergaard
Marina Kjaergaard
Global Obesity and Liver Disease Research, Novo Nordisk A/S, Måløv, Denmark
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://ir.akerotx.com/news-releases/news-release-details/all-akr-001-dose-groups-met-week-12-efficacy-endpoints-nash ) 72 Hansen AMK Vienberg SG Lykkegaard K Zhao X Tingqing G Han D Zhang X Thogersen H Sass-Orum K Tagmose T , Differential receptor selectivity of the FGF15/FGF19 orthologues
Wenqi Yang
Wenqi Yang
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sports University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Ling Liu
Ling Liu
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Yuan Wei
Yuan Wei
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sports University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Chunlu Fang
Chunlu Fang
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sports University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Fu Zhou
Fu Zhou
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Jinbao Chen
Jinbao Chen
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Qinghua Han
Qinghua Han
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Meifang Huang
Meifang Huang
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Xuan Tan
Xuan Tan
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Qiuyue Liu
Qiuyue Liu
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Qiang Pan
Qiang Pan
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Lu Zhang
Lu Zhang
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Xiaojuan Lei
Xiaojuan Lei
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Liangming Li
Liangming Li
Center for Scientific Research and Institute of Exercise and Health, Guangzhou Sports University, Guangzhou, China
Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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Key Laboratory of Sports Technique, Tactics and Physical Function of General Administration of Sport of China, Scientific Research Center, Guangzhou Sport University, Guangzhou, China
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.1210/en.2012-1193 22778214 22 Zhao Y Meng C Wang Y Huang H Liu W Zhang JF Zhao H Feng B Leung PS Xia Y . IL-1beta inhibits beta-klotho expression and FGF19 signaling in hepatocytes . American Journal of Physiology: Endocrinology and Metabolism 2016
Linfei Yang
Linfei Yang
Center for Medical Experiments, The Third Xiangya Hospital, Central South University, Changsha, China
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Xiao Yu
Xiao Yu
Department of General Surgery, The Third Xiangya Hospital, Central South University, Changsha, China
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Yongchao Yang
Yongchao Yang
Department of Burns and Plastic Surgery, The Third Xiangya Hospital, Central South University, Changsha, China
European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
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European Pancreas Center, Department of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, Heidelberg, Germany
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. Non-cell-autonomous activation of IL-6/STAT3 signaling mediates FGF19-driven hepatocarcinogenesis. Nature Communications 2017 8 15433 . ( https://doi.org/10.1038/ncomms15433 ) 38 Kishi Y Okudaira S Tanaka M Hama K Shida D Kitayama J Yamori T
Mohammed S Razzaque
Mohammed S Razzaque
Department of Pathology, Lake Erie College of Osteopathic Medicine, Erie, Pennsylvania, USA
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effects on the musculoskeletal system, the neuronal system, the immune system, and inflammatory pathways ( 1 , 4 , 34 , 62 , 63 , 64 , 65 , 66 ). FGF23 FGF23 is a member of the endocrine FGF family, along with FGF19 and FGF21 ( 9
Maximilian Bielohuby
Maximilian Bielohuby
Sanofi-Aventis Deutschland GmbH, R&D, Industriepark Höchst, Frankfurt, Germany
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Martin Bidlingmaier
Martin Bidlingmaier
Endocrine Research Laboratories, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany
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Uwe Schwahn
Uwe Schwahn
Sanofi-Aventis Deutschland GmbH, R&D, Industriepark Höchst, Frankfurt, Germany
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Blouet C Chang JK Chua S Jr. Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism . Molecular Metabolism 2014 3 19 – 28 . ( https://doi.org/10.1016/j.molmet.2013.10.002 ) 24567901 10.1016/j
Jonathan Hazlehurst
Jonathan Hazlehurst
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Bernard Khoo
Bernard Khoo
Endocrinology, Division of Medicine, University College London, London, UK
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Carolina Brito Lobato
Carolina Brito Lobato
Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
Department of Medicine, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark
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Department of Medicine, Copenhagen University Hospital – Amager and Hvidovre, Hvidovre, Denmark
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Ibiyemi Ilesanmi
Ibiyemi Ilesanmi
Section of Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK
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Sally Abbott
Sally Abbott
Department of Dietetics, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK
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Tin Chan
Tin Chan
Faculty of Medicine, Chinese University of Hong Kong, Hong Kong
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Sanesh Pillai
Sanesh Pillai
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Kate Maslin
Kate Maslin
School of Nursing and Midwifery, University of Plymouth, Plymouth, UK
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Sanjay Purkayastha
Sanjay Purkayastha
Brunel University, London, UK
Imperial College Healthcare NHS Trust, St Mary’s Hospital, London, UK
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Imperial College Healthcare NHS Trust, St Mary’s Hospital, London, UK
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Barbara McGowan
Barbara McGowan
Endocrinology, Guys’ and St Thomas’s NHS Foundation Trust, London, UK
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Rob Andrews
Rob Andrews
University of Exeter Medical School, Exeter, UK
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Eveleigh Nicholson
Eveleigh Nicholson
Portsmouth Hospitals University NHS Trust, Portsmouth, UK
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Katherine McCullough
Katherine McCullough
Royal Surrey County Hospital, Guildford, UK
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Lorraine Albon
Lorraine Albon
University Hospitals Sussex NHS Foundation Trust, Worthing, UK
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Rachel Batterham
Rachel Batterham
Endocrinology, Division of Medicine, University College London, London, UK
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Georgios K Dimitriadis
Georgios K Dimitriadis
King's College Hospital NHS Foundation Trust, London, UK
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Shareen Forbes
Shareen Forbes
BHF Centre for Cardiovascular Science, Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
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Gavin Bewick
Gavin Bewick
School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK
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Tricia M-M Tan
Tricia M-M Tan
Section of Endocrinology and Investigative Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK
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( 10 , 11 , 12 , 13 ), alterations in bile acid kinetics ( 14 ) which may in turn trigger excess FGF-19 secretion ( 15 ), and inflammatory cytokines such as IL-1beta ( 16 ). PBH is also known as ‘late dumping syndrome’. This phenomenon was first
