Search Results

You are looking at 1 - 10 of 23 items for :

  • "Cushing’s disease" x
Clear All
Open access

Alberto Giacinto Ambrogio, Massimiliano Andrioli, Martina De Martin, Francesco Cavagnini and Francesca Pecori Giraldi

Introduction First-line treatment of Cushing’s disease is surgical removal of the ACTH-secreting pituitary tumor and worldwide remission rates range from 60 to 80% ( 1 , 2 , 3 ). The tumor may recur, however, most often within two years of

Open access

Prachi Bansal, Anurag Lila, Manjunath Goroshi, Swati Jadhav, Nilesh Lomte, Kunal Thakkar, Atul Goel, Abhidha Shah, Shilpa Sankhe, Naina Goel, Neelam Jaguste, Tushar Bandgar and Nalini Shah

Introduction Cushing’s disease (CD) is a state of cortisol excess, caused by an ACTH-secreting pituitary adenoma. Although a rare disease with an annual incidence of 1.5 patients/million ( 1 ), it is associated with significant morbidity and

Open access

Emmanuelle Motte, Anya Rothenbuhler, Stephan Gaillard, Najiba Lahlou, Cécile Teinturier, Régis Coutant and Agnès Linglart

Introduction Cushing’s disease (CD) is characterized by adrenocorticotropin (ACTH)-dependent cortisol excess originating from a pituitary adenoma and accounts for approximately 85% of cases of pediatric Cushing’s syndrome ( 1 , 2 , 3 , 4

Open access

Nidan Qiao

Introduction Cushing’s disease (CD) is a subtype of pituitary adenoma with hypercortisolism and presents a particular challenge to neurosurgeons. Transsphenoidal surgery (TS) has long been the standard of care for patients with CD ( 1 , 2

Open access

Lang Qin, Xiaoming Zhu, Xiaoxia Liu, Meifang Zeng, Ran Tao, Yan Zhuang, Yiting Zhou, Zhaoyun Zhang, Yehong Yang, Yiming Li, Yongfei Wang and Hongying Ye

Introduction Hypertension is a common chronic condition in patients with Cushing’s disease (CD) and may be the first sign ( 1 ). The pathogenesis of glucocorticoid-induced hypertension is not fully understood. It is thought to be related in

Open access

Anastasia P Athanasoulia-Kaspar, Matthias K Auer, Günter K Stalla and Mira Jakovcevski

premature aging by inducing accelerated telomere shortening, which might be an explanation for persistent high morbidity and other clinical consequences associated with Cushing’s disease, even years after successful treatment for hypercortisolism. This

Open access

Kush Dev Singh Jarial, Anil Bhansali, Vivek Gupta, Paramjeet Singh, Kanchan K Mukherjee, Akhilesh Sharma, Rakesh K Vashishtha, Suja P Sukumar, Naresh Sachdeva and Rama Walia

% diagnostic accuracy ( 1 ). Cushing’s disease (CD) accounts for about 90–95% of the cases when there is no obvious source of ACTH hypersecretion, and this distinction is essential to decide further therapeutic strategies ( 2 , 3 , 4 , 5 ). Sellar imaging

Open access

Benedetta Zampetti, Erika Grossrubatscher, Paolo Dalino Ciaramella, Edoardo Boccardi and Paola Loli

use of more stringent criteria to define responsiveness to the diagnostic tests increases the ability to differentiate Cushing’s disease (CD) from EAS, but invariably leads to reduced diagnostic sensitivity ( 12 ). On the other hand, dynamic gadolinium

Open access

Paula Bruna Araujo, Leandro Kasuki, Carlos Henrique de Azeredo Lima, Liana Ogino, Aline H S Camacho, Leila Chimelli, Márta Korbonits and Monica R Gadelha

with micro or macroadenomas diagnosed until 18 years of age were included. Of these patients, 74 (56%) had acromegaly or gigantism, 38 (28.8%) had prolactinoma, 10 (7.6%) had non-functioning pituitary adenoma (NFPA) and 10 (7.6%) had Cushing’s disease

Open access

Adrian F Daly, David A Cano, Eva Venegas-Moreno, Patrick Petrossians, Elena Dios, Emilie Castermans, Alvaro Flores-Martínez, Vincent Bours, Albert Beckers and Alfonso Soto-Moreno

Introduction Clinically apparent pituitary adenomas are present in about 1:1000 of the general population in Europe; the most frequent sub-types are prolactinomas, non-secreting adenomas and somatotropinomas, while Cushing’s disease and